[MCQ] Disorders of Absorption- Part 6

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Disorders of Absorption- Part 6

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Question 1

Complications associated with untreated celiac disease include ?

A	Infertility or recurrent abortion
B	Impaired splenic function
C	Neurologic disorders
D	All of the above

Question 1 Explanation:

Complications associated with untreated celiac disease include osteoporosis, impaired splenic function, neurologic disorders, infertility or recurrent abortion, ulcerative jejunoileitis, and cancer. Enteropathy-associated T-cell lymphoma and adenocarcinoma of the jejunum are rare complications of celiac disease

Question 2

Endocrine and metabolic disorders that can cause malabsorption syndrome include ?

A	Hypoparathyroidism
B	Hyperthyroidism
C	Carcinoid syndrome
D	All of the above

Question 2 Explanation:

Endocrine & metabolic disorders that can cause malabsorption syndrome include diabetes, hypoparathyroidism, adrenal insufficiency, hyperthyroidism & carcinoid syndrome.

Question 3

Circulatory disorders that can cause malabsorption syndrome include ?

A	Congestive heart failure
B	Constrictive pericarditis
C	Mesenteric artery atherosclerosis
D	All of the above

Question 4

Dermatitis in malabsorption syndrome is due to deficiency of ?

A	Vitamin A
B	Zinc
C	Essential fatty acid
D	All of the above

Question 5

Glossitis, cheilosis, stomatitis in malabsorption syndrome is due to deficiency of ?

A	Iron
B	Vitamin B12, folate
C	Vitamin A
D	All of the above

Question 6

Chronic diarrhea in a tropical environment is most often caused by all except ?

A	Yersinia enterocolitica
B	Cryptosporidium parvum
C	Giardia lamblia
D	Giardia lamblia

Question 6 Explanation:

Chronic diarrhea in a tropical environment is most often caused by G. lamblia, Yersinia enterocolitica, C. difficile, Cryptosporidium parvum and Cyclospora cayetanensis.

Question 7

Patients of Tropical sprue are rarely found in ?

A	South India
B	Philippines
C	Caribbean islands
D	Africa

Question 8

Patients of Tropical sprue are rarely found in ?

A	South India
B	Philippines
C	Caribbean islands
D	Africa

Question 9

Treatment of Tropical sprue includes ?

A	Gluten-free diet
B	Broad-spectrum antibiotics
C	Glucocorticoids
D	All of the above

Question 9 Explanation:

Broad-spectrum antibiotics and folic acid are curative in tropical sprue

Question 10

Diseases that may arise following small-intestinal resection include all except ?

A	Colonic diverticulosis
B	Cholesterol gall stones
C	Gastric hypersecretion of acid
D	Hyperoxaluria

Question 10 Explanation:

Following large resections of small intestine, enteric hyperoxaluria, cholesterol gallstones and gastric hypersecretion of acid occurs.

Question 11

Enteric hyperoxaluria is best treated with ?

A	Allopurinol
B	Aspirin
C	Codeine
D	Cholestyramine

Question 11 Explanation:

Cholestyramine, an anion-binding resin & calcium are useful in reducing hyperoxaluria.

Question 12

Which of the following hormones has a role in the treatment of short bowel syndrome ?

A	Glucagon-like peptide 2 (GLP-2)
B	VIP
C	Cholecystokinin
D	TSH

Question 12 Explanation:

Potential effectiveness of hormones like glucagon-like peptide-2 (GLP-2), epidermal growth factor (EGF) & growth hormone (GH) is being studied in short bowel syndrome.

Question 13

Stagnant bowel or blind loop syndrome refers to ?

A	Stasis due to impaired peristalsis
B	Changes in intestinal anatomy
C	Direct communication between small & large intestine
D	All of the above

Question 13 Explanation:

Bacterial proliferation in bacterial overgrowth syndrome or stagnant bowel syndrome or blind loop syndrome is due to stasis caused by impaired peristalsis (functional stasis), changes in intestinal anatomy (anatomic stasis) or direct communication between small and large intestine

Question 14

Diagnosis of the bacterial overgrowth syndrome is done by all except ?

A	Low serum cobalamin level
B	Low serum folate level
C	Increased aerobic &/or anaerobic colonic-type bacteria in jejunal aspirate
D	Schilling test

Question 14 Explanation:

Diagnosis of the bacterial overgrowth syndrome is done by a low serum cobalamin level, elevated serum folate level, increased levels of aerobic and/or anaerobic colonic-type bacteria in a jejunal aspirate, Schilling test. Following tetracycline for 5 days, Schilling test will become norma

Question 15

For frequent recurrences of bacterial overgrowth syndrome, which of the following treatment strategies is most effective ?

A	Antibiotics for 1 week per month
B	Antibiotics for ~3 weeks
C	Antibiotics until symptoms remit
D	Antibiotics continuously

Question 15 Explanation:

In the presence of frequent recurrences, use of antibiotics for 1 week per month whether or not symptoms are present is most effective

Question 16

Whipple’s disease is caused by the bacteria named ?

A	Tropheryma whippeli
B	Treponema whippeli
C	Toxoplasma whippeli
D	Trenoderma whippeli

Question 16 Explanation:

Whipple’s disease is a chronic multisystem disease that presents as diarrhea, steatorrhea, weight loss, arthralgia & CNS and cardiac problems. It is caused by bacteria Tropheryma whipplei.

Question 17

Which of the following statements about Tropheryma whippeli is false ?

A	Gram-positive
B	Actinobacterium
C	Low virulence, low infectivity
D	PAS+ macrophages in small intestine

Question 17 Explanation:

Hallmark of Whipple’s disease is the presence of PAS-positive macrophages in small intestine. T. whipplei is a small gram-positive, actinobacterium bacillus, with low virulence but high infectivity

Question 18

Which of the following about Whipple’s disease is false ?

A	Multisystem disease
B	T. whippelii outside macrophages indicates active disease
C	T. whipplei cannot be grown on culture
D	Drug of first choice is TMP/SMX for 1 year

Question 18 Explanation:

Presence of T. whipplei bacillus outside of macrophages is a more important indicator of active disease than within macrophages. T. whipplei has been grown in culture. The current drug of choice is double-strength trimethoprim/sulfamethoxazole for ~1 year.

Question 19

Which of the following about Whipple’s disease is false ?

A	Drug of second choice is Chloramphenicol
B	Antibiotic therapy has to be prolonged
C	Disease recurrence with dementia is a poor prognostic sign
D	None of the above

Question 19 Explanation:

If TMP/SMX is not tolerated, chloramphenicol is an appropriate second choice. Recurrence of disease activity, especially with dementia, is an extremely poor prognostic sign.

Question 20

Which of the following is the most common neurologic manifestations of classic Whipple’s disease ?

A	Cognitive change
B	Supranuclear ophthalmoplegia
C	Oculomasticatory or oculofacialskeletal myorhythmia
D	Ataxia

Question 20 Explanation:

Cognitive changes and later dementia are commonest neurologic signs. Movement disorders of eye muscles (oculomasticatory or oculofacioskeletal myorhythmia) are considered pathognomonic for Whipple’s disease

Question 21

Which of the following about protein-losing enteropathy is false ?

A	Excess protein loss into gastrointestinal tract
B	Low serum albumin & globulin in absence of renal & hepatic disease
C	α1-antitrypsin clearance can be useful in diagnosis
D	Lymphocytosis supports diagnosis

Question 21 Explanation:

Protein-losing enteropathy is characterized by excess protein loss into gastrointestinal tract. With loss of protein, peripheral lymphocytes are also lost via lymphatics, resulting in a relative lymphopenia. Thus, presence of lymphopenia in a patient with hypoproteinemia supports the presence of increased loss of protein into gastrointestinal tract

Question 22

Which of the following can cause protein-losing enteropathy ?

A	Peripheral vascular disease
B	Chronic pericarditis
C	Hemolytic uremic syndrome
D	Hypothyroidism

Question 23

Hypoproteinemia in intestinal lymphangiectasia should be treated with ?

A	SCFA
B	MCT
C	LCFA
D	All of the above

Question 23 Explanation:

Treatment of hypoproteinemia in intestinal lymphangiectasia is done by low-fat diet and administration of MCTs, which do not exit from intestinal epithelial cells via lymphatics but are delivered to the body via portal vein.

Question 24

Adherence to colonic mucin by E. histolytica trophozoites is mediated by ?

A	Gal/GalNAc–specific lectin
B	Gal/GalNAc–specific pepsin
C	Gal/GalNAc–specific trypsin
D	Gal/GalNAc–specific capsin

Question 25

Adherence to colonic mucin by E. histolytica trophozoites is mediated by ?

A	Gal/GalNAc–specific lectin
B	Gal/GalNAc–specific pepsin
C	Gal/GalNAc–specific trypsin
D	Gal/GalNAc–specific capsin

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See all quizzes of Peptic Ulcer Disease at here:

1.Complications associated with untreated celiac disease include ?
A. Infertility or recurrent abortion

B. Impaired splenic function
C. Neurologic disorders
D. All of the above

2. Endocrine and metabolic disorders that can cause
malabsorption syndrome include ?
A. Hypoparathyroidism
B. Hyperthyroidism
C. Carcinoid syndrome
D. All of the above

3. Circulatory disorders that can cause malabsorption syndrome
include ?
A. Congestive heart failure
B. Constrictive pericarditis
C. Mesenteric artery atherosclerosis
D. All of the above
4. Dermatitis in malabsorption syndrome is due to deficiency of ?
A. Vitamin A
B. Zinc
C. Essential fatty acid
D. All of the above
5. Glossitis, cheilosis, stomatitis in malabsorption syndrome is
due to deficiency of ?
A. Iron
B. Vitamin B12, folate
C. Vitamin A
D. All of the above
6. Chronic diarrhea in a tropical environment is most often caused
by all except ?
A. Yersinia enterocolitica
B. Cryptosporidium parvum
C. Giardia lamblia
D. Entamoeba histolytica

7. Patients of Tropical sprue are rarely found in ?
A. South India
B. Philippines
C. Caribbean islands
D. Africa

8. Treatment of Tropical sprue includes ?
A. Gluten-free diet
B. Broad-spectrum antibiotics
C. Glucocorticoids
D. All of the above

9.Diseases that may arise following small-intestinal resection
include all except ?
A. Colonic diverticulosis
B. Cholesterol gall stones
C. Gastric hypersecretion of acid
D. Hyperoxaluria

10. Enteric hyperoxaluria is best treated with ?
A. Allopurinol
B. Aspirin
C. Codeine
D. Cholestyramine

11. Which of the following hormones has a role in the treatment of
short bowel syndrome ?
A. Glucagon-like peptide 2 (GLP-2)
B. VIP
C. Cholecystokinin
D. TSH

12.Stagnant bowel or blind loop syndrome refers to ?
A. Stasis due to impaired peristalsis
B. Changes in intestinal anatomy
C. Direct communication between small & large intestine
D. All of the above

13. Diagnosis of the bacterial overgrowth syndrome is done by all
except ?
A. Low serum cobalamin level
B. Low serum folate level
C. Increased aerobic &/or anaerobic colonic-type bacteria in
jejunal aspirate

D. Schilling test

14. For frequent recurrences of bacterial overgrowth syndrome,
which of the following treatment strategies is most effective ?
A. Antibiotics for 1 week per month
B. Antibiotics for ~3 weeks
C. Antibiotics until symptoms remit
D. Antibiotics continuously

15. Whipple’s disease is caused by the bacteria named ?
A. Tropheryma whippeli
B. Treponema whippeli
C. Toxoplasma whippeli
D. Trenoderma whippeli

16. Which of the following statements about Tropheryma whippeli
is false ?
A. Gram-positive
B. Actinobacterium
C. Low virulence, low infectivity
D. PAS+ macrophages in small intestine

17.Which of the following about Whipple’s disease is false ?
A. Multisystem disease
B. T. whippelii outside macrophages indicates active disease
C. T. whipplei cannot be grown on culture
D. Drug of first choice is TMP/SMX for 1 year

18. Which of the following about Whipple’s disease is false ?
A. Drug of second choice is Chloramphenicol
B. Antibiotic therapy has to be prolonged
C. Disease recurrence with dementia is a poor prognostic sign
D. None of the above

19. Which of the following is the most common neurologic
manifestations of classic Whipple’s disease ?

A. Cognitive change
B. Supranuclear ophthalmoplegia
C. Oculomasticatory or oculofacialskeletal myorhythmia
D. Ataxia

20. Which of the following about protein-losing enteropathy is
false ?
A. Excess protein loss into gastrointestinal tract
B. Low serum albumin & globulin in absence of renal & hepatic disease
C.  1-antitrypsin clearance can be useful in diagnosis
D. Lymphocytosis supports diagnosis

21. Which of the following can cause protein-losing enteropathy ?
A. Peripheral vascular disease
B. Chronic pericarditis
C. Hemolytic uremic syndrome
D. Hypothyroidism
22. Hypoproteinemia in intestinal lymphangiectasia should be
treated with ?
A. SCFA
B. MCT
C. LCFA
D. All of the above

23.Adherence to colonic mucin by E. histolytica trophozoites is
mediated by ?
A. Gal/GalNAc–specific lectin
B. Gal/GalNAc–specific pepsin
C. Gal/GalNAc–specific trypsin
D. Gal/GalNAc–specific capsin

Disorders of Absorption

[MCQ] Disorders of Absorption- Part 6

I. Start the exam by click the “Start” button

Disorders of Absorption- Part 6

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