[MCQs] Blood Coagulation Quiz – Part 1 (25 test)

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1. Hemostasis:

1. Plays a small part in stopping the flow of blood.
2. Plays a large part in stopping the flow of blood.
3. Is a vascular system.
4. Represents 15-20% of platelet protein.

2. Coagulation is one component in:

1. Fibrinolysis.
2. Hemostasis.
3. Disruption of the intrinsic system.
4. Vascular dilatation.

3. What major role does blood platelets perform?

1. In the hemostatic process, blood platelets swell, congeal, and adhere to blood vessel wall to plug the site of the injury.
2. They contract.
3. They stimulate collagen.
4. Platelets extend pseudopodia.

4. Which occurs last in the clotting process?

1. Formation of thrombin.
2. Formation of thromboplastin.
3. Aggregation of platelets.
4. Formation of fibrin network.

5. Coagulation factors I through IV are, respectively:

1. Calcium, fibrinogen, prothrombin, and Christmas.
2. Fibrinogen, prothrombin, thromboplastin, and calcium.
3. Prothrombin, calcium, fibrinogen, and thromboplastin.
4. Thromboplastin, prothrombin, calcium, and fibrinogen.

6. Which is the Stuart Prower Factor?

1. Factor V.
2. Factor VII.
3. Factor X.
4. Factor XIII

7. Thromboplastin eliminates the need for what item in stage I?

1. Globulin.
2. The accelerator, proconvertin.
3. High concentration of serum and plasma.
4. Platelets.

8. What are the two systems that make up the coagulation process?

1. Vascular and hemolysis.
2. Extrinsic and intravascular.
3. Intravascular and vascular.
4. Intrinsic and extrinsic.

9. Coagulation factor XIII produces a tough gel through:

1. Increasing the serum content.
2. Stabilizing serum.
3. Converting a loosely linked fibrin clot with the help of calcium ions.
4. Decreasing the conversion of prothrombin with the help of calcium ions.

10. The synthesis of prothrombin takes place in the liver and requires the presence of:

1. Folic acid.
2. Vitamin A.
3. Vitamin B12.
4. Vitamin K.

11. Prothrombin is the precursor of:

1. Fibrin.
2. Fibrinogen.
3. Thrombin.
4. Thromboplastin.

12. A___________ deficiency is unlikely to interfere with coagulation because clinical tetany would intervene.

1. Calcium.
2. Fibrinogen.
3. Prothrombin.
4. Factor VIII.

13. Which factor is thought to be an accelerator in the conversion of prothrombin to thrombin?

1. Factor VII.
2. Factor VIII.
3. Factor IX.
4. Factor XII.

14. Which is consumed during the clotting process and is therefore not present in serum?

1. Factor V.
2. Factor VII.
3. Factor IX.
4. Factor XI.

15. Which platelet factor activates prothrombin?

1. 2
2. 3
3. 4
4. 7

16. Hemophilias A and B are hereditary deficiencies of which coagulation factors, respectively?

1. VII and IX.
2. VIII and IX.
3. XI and VIII.
4. XI and IX.

17. Platelet factor 3 is found in the platelet and is a ______________ component of platelets.

1. Membrane; extrinsic.
2. Plasma; extrinsic.
3. Membrane; intrinsic.
4. Plasma; intrinsic.

18. A fibrin clot is ultimately formed by the interaction of fibrinogen and:

1. Calcium.
2. Thrombin.
3. Thromboplastin.
4. Platelets.

19. The formation of thrombin from prothrombin occurs in what stage?

1. Stage I
2. Stage II
3. Stage III
4. Stage IV

20. During the clot lysis stage, what happens to the blood clot when plasmin interacts with it?

1. Enlarges.
2. Shrivels up like an old red blood cell.
3. Enlongates like an ameoba.
4. Dissolves into fragments.

21. One anticoagulant that inhibits the clotting activity of blood is:

1. Coumarin derivitives.
2. Fibrin.
3. Throboplastin.
4. Proconvertin.

22. In the Ivy method for determining the bleeding time, the blood pressure cuff is inflated to:

1. 20 mm Hg.
2. 30 mm Hg.
3. 40 mm Hg.
4. 50 mm Hg.

23. The normal bleeding time with the Ivy method is:

1. Up to 8 minutes.
2. 3-10 minutes.
3. 10-15 minutes.
4. 15-20 minutes.

24. What should be the temperature of the water bath for the whole blood clotting time? (NOTE: The whole blood clotting time discussed in paragraph 2-12 of the text is also referred to as the coagulation time or clotting time.)

1. 10^oC
2. 20^oC
3. 37^oC
4. 56^oC

25. All of the variables listed below decrease the clotting time of whole blood except:

1. Excessive agitation of the blood specimen.
2. Air bubbles in the blood.
3. Tissue fluid in the blood.
4. Performing test at room temperature.