The quizzes about Cerebrospinal Fluid

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The quizzes about Cerebrospinal Fluid
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Select the one best response to each question!

Myeloblasts are seen in the CSF:


1. The functions of the CSF include all of the following except:
A. Removal of metabolic wastes
B. Producing an ultrafiltrate of plasma
C. Supplying nutrients to the CNS
D. Protection of the brain and spinal cord
2. The CSF flows through the:
A. Choroid plexus
B. Pia mater
C. Arachnoid space
D. Dura mater
3. Substances present in the CSF are contolled by the:
A. Arachnoid granulations
B. Blood-brain barrier
C. Presence of one-way valves
D. Blood-CSF barrier
4. The CSF tube labeled 3 is sent to:
A. The hematology department
B. The chemistry department
C. The microbiology department
D. The serology department
5. The CSF tube that should be refrigerated is:
A. Tube 1
B. Tube 2
C. Tube 3
D. Tube 4
6. Place the appropriate letter in front of the statement that best describes CSF specimens in these two conditions:
A. Traumatic tap
B. Intracranial hemorrhage
_____Even distribution of blood in all tubes
_____Xanthochromic supernatant
_____Concentration of blood in tube 1 is greater than in tube 3
_____Specimen contains clots
7. The presence of xanthochromia can be caused by all of the following except:
A. Immature liver function
B. RBC degradation
C. A recent hemorrhage
D. Elevated CSF protein
8. A web-like pellicle in a refrigerated CSF specimen is indicative of:
A. Tubercular meningitis
B. Multiple sclerosis
C. Primary CNS malignancy
D. Viral meningitis
9. Given the following information, calculate the CSF WBC count: cells counted, 80; dilution, 1:10; large
Neubauer squares counted, 10.
A. 8
B. 80
C. 800
D. 8000
10. A CSF WBC count is diluted with:
A. Distilled water
B. Normal saline
C. Acetic acid
D. Methylene blue
11. A total CSF cell count on a clear fluid should be:
A. Reported as normal
B. Not reported
C. Diluted with normal saline
D. Counted undiluted
12. The purpose of adding albumin to CSF before cytocentrifugation is to:
A. Increase the cell yield
B. Decrease the cellular distortion
C. Improve the cellular staining
D. Both A and B
13. The primary concern when pleocytosis of neutrophils and lymphocytes is found in the CSF is:
A. Meningitis
B. CNS malignancy
C. Multiple sclerosis
D. Hemorrhage
14. Neutrophils with pyknotic nuclei may be mistaken for:
A. Lymphocytes
B. Nucleated RBCs
C. Malignant cells
D. Spindle-shaped cells
15. The presence of which of the following cells is increased when a CNS shunt malfunctions?
A. Neutrophils
B. Macrophages
C. Eosinophils
D. Lymphocytes
16. Macrophages appear in the CSF following:
A. Hemorrhage
B. Repeated spinal taps
C. Diagnostic procedures
D. All of the above
17. Nucleated RBCs are seen in the CSF as a result of:
A. Elevated blood RBCs
B. Treatment of anemia
C. Severe hemorrhage
D. Bone marrow contamination
18. Following a CNS diagnostic procedure, which of the following might be seen in the CSF?
A. Choroidal cells
B. Ependymal cells
C. Spindle-shaped cells
D. All of the above
19. Hemosiderin granules and hematoidin crystals are seen in:
A. Lymphocytes
B. Macrophages
C. Ependymal cells
D. Neutrophils
20. Myeloblasts are seen in the CSF:
A. In bacterial infections
B. In conjunction with CNS malignancy
C. Following cerebral hemorrhage
D. As a complication of acute leukemia
21. Cells resembling large and small lymphocytes with cleaved nuclei represent:
A. Lymphoma cells
B. Choroid cells
C. Melanoma cells
D. Medulloblastoma cells
22. The normal value of CSF protein is:
A. 6–8 g/dL
B. 15–45 g/dL
C. 6–8 mg/dL
D. 15–45 mg/dL
23. CSF can be differentiated from plasma by the presence of:
A. Albumin
B. Globulin
C. Prealbumin
D. Tau transferrin
24. In plasma, the second most prevalent protein is IgG; in CSF, the second most prevalent protein is:
A. Transferrin
B. Prealbumin
C. IgA
D. Ceruloplasmin
25. Elevated CSF protein values can be caused by all of the following except:
A. Meningitis
B. Multiple sclerosis
C. Fluid leakage
D. CNS malignancy
26. The integrity of the blood-brain barrier is measured using the:
A. CSF/serum albumin index
B. CSF/serum globulin ratio
C. CSF albumin index
D. CSF IgG index
27. Given the following results, calculate the IgG index: CSF IgG, 50 mg/dL; serum IgG, 2 gm/dL; CSF albumin, 70 mg/dL; serum albumin, 5 gm/dL.
A. 0.6
B. 6.0
C. 1.8
D. 2.8
28. The CSF IgG index calculated in Study Question 27 is indicative of:
A. Synthesis of IgG in the CNS
B. Damage to the blood-brain barrier
C. Cerebral hemorrhage
D. Lymphoma infiltration
29. The finding of oligoclonal bands in the CSF and not in the serum is seen with:
A. Multiple myeloma
B. CNS malignancy
C. Multiple sclerosis
D. Viral infections
30. A CSF glucose of 15 mg/dL, WBC count of 5000, 90% neutrophils, and protein of 80 mg/dL is suggestive of:
A. Fungal meningitis
B. Viral meningitis
C. Tubercular meningitis
D. Bacterial meningitis
31. A patient with a blood glucose of 120 mg/dL would have a normal CSF glucose of:
A. 20 mg/dL
B. 60 mg/dL
C. 80 mg/dL
D. 120 mg/dL
32. CSF lactate will be more consistantly decreased in:
A. Bacterial meningitis
B. Viral meningitis
C. Fungal meningitis
D. Tubercular meningitis
33. Measurement of which of the following can be replaced by CSF glutamine analysis in children with Reye syndrome?
A. Ammonia
B. Lactate
C. Glucose
D. -ketoglutarate
34. Prior to performing a Gram stain on CSF, the specimen must be:
A. Filtered
B. Warmed to 37C
C. Centrifuged
D. Mixed
35. All of the following statements are true about cryptoccocal meningitis except:
A. An India Ink preparation is positive
B. A starburst pattern is seen on Gram stain
C. The WBC count is over 2000
D. A confirmatory immunology test is available
36. The test of choice to detect neurosyphilis is the:

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