1.The more lipophylic drugs:
a) Are more potent
b) Have longer duration of action
c) Bind more extensively to proteins
d) All of the above
2.. Which of the following fibers is the first to be blocked?
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a) Type A alpha fibers
b) B and C fibers
c) Type A beta fibers
d) Type A gamma fibers
3.. Indicate the function, which the last to be blocked:
a) Pain, temperature
b) Muscle spindles
c) Motor function
d) Touch, pressure
4. Which of the following fibers participates in high-frequency pain transmission?
a) Type A delta and C fibers
b) Type A alpha fibers
c) Type B fibers
d) Type A beta fibers
5. Which of the following local anesthetics is an useful antiarrhythmic agent?
a) Cocaine
b) Lidocaine
c) Bupivacaine
d) Ropivacaine
6. Indicate the route of local anesthetic administration, which is associated with instillation within epidural or subarachnoid
spaces:
a) Topical anesthesia
b) Infiltrative anesthesia
c) Regional anesthesia
d) Spinal anesthesia
7. The choice of a local anesthetic for specific procedures is usually based on:
a) The duration of action
b) Water solubility
c) Capability of rapid penetration through the skin or mucosa with limited tendency to diffuse away from the site of
application
d) All of the above
8. Which of the following local anesthetics is a short-acting drug?
a) Procaine
b) Tetracaine
c) Bupivacaine
d) Ropivacaine
9. Indicate the local anesthetic, which is a long-acting agent:
a) Lidocaine
b) Bupivacaine
c) Procaine
d) Mepivacaine
10. The anesthetic effect of the agents of short and intermediate duration of action can not be prolonged by adding:
a) Epinephrine
b) Norepinephrine
c) Dopamine
d) Phenylephrine
11. A vasoconstrictor does not:
a) Retard the removal of drug from the injection site
b) Hence the chance of toxicity
c) Decrease the blood level
d) Reduce a local anesthetic uptake by the nerve
12. Vasoconstrictors are less effective in prolonging anesthetic properties of:
a) Procaine
b) Bupivacaine
c) Lidocaine
d) Mepivacaine
13. Which of the following local anesthetics is only used for surface or topical anesthesia?
a) Cocaine
b) Tetracaine
c) Procaine
d) Bupivacaine
14. Indicate the local anesthetic, which is mainly used for regional nerve block anesthesia:
a) Dibucaine
b) Bupivacaine
c) Tetracaine
d) Cocaine
15. Which of the following local anesthetics is used for infiltrative and regional anesthesia?
a) Procaine
b) Lidocaine
c) Mepivacaine
d) All of the above
16. Indicate the local anesthetic, which is used for spinal anesthesia:
a) Tetracaine
b) Cocaine
c) Dibucaine
d) Bupivacaine
17. Which of the following local anesthetics is called a universal anesthetic?
a) Procaine
b) Ropivacaine
c) Lidocaine
d) Bupivacaine
18. Most serious toxic reaction to local anesthetics is:
a) Seizures
b) Cardiovascular collapse
c) Respiratory failure
d) All of the above
19. Correct statements concerning cocaine include all of the following EXCEPT:
a) Cocaine is often used for nose and throat procedures
b) Limited use because of abuse potential
c) Myocardial depression and peripheral vasodilatation
d) Causes sympathetically mediated tachycardia and vasoconstriction
20. Which of the following local anesthetics is more cardiotoxic?
a) Procaine
b) Bupivacaine
c) Lidocaine
d) Mepivacaine
21. Most local anesthetics can cause:
a) Depression of abnormal cardiac pacemaker activity, excitability, conduction
b) Depression of the strength of cardiac contraction
c) Cardiovascular collapse
d) All of the above
22. Which one of the following local anesthetics causes methemoglobinemia?
a) Prilocaine
b) Procaine
c) Lidocaine
d) Ropivacaine
23. Procaine has all of the following properties EXCEPT:
a) It has ester linkage
b) Its metabolic product can inhibit the action of sulfonamides
c) It readily penetrates the skin and mucosa
d) It is relatively short-acting
24. Correct statements concerning lidocaine include all of the following EXCEPT:
a) It is an universal anesthetic
b) It has esteratic linkage
c) It widely used as an antiarrhythmic agent
d) It is metabolized in liver
25. Which of the following local anesthetics is more likely to cause allergic reactions?
a) Lidocaine
b) Bupivacaine
c) Procaine
d) Ropivacaine
26. Tetracaine has all of the following properties EXCEPT:
a) Slow onset
b) Low potency
c) Long duration
d) High toxicity
27. Correct statements concerning bupivacaine include all of the following EXCEPT:
a) It has low cardiotoxicity
b) It has amide linkage
c) It is a long-acting drug
d) An intravenous injection can lead to seizures
