I. Start the exam by click the “Start” button
The Pathogenesis, Prevention, and Treatment of Atherosclerosis- Part 1
See all quizzes of The Pathogenesis, Prevention, and Treatment of Atherosclerosis at here:
The Pathogenesis, Prevention, and Treatment of Atherosclerosis – Part 1| The Pathogenesis, Prevention, and Treatment of Atherosclerosis – Part 2| The Pathogenesis, Prevention, and Treatment of Atherosclerosis – Part 3
1.Major lipid of lipoproteins is ?
A. Cholesterol
B. Triglycerides
C. Phospholipids
D. All of the above
2.Lipoproteins have been classified on the basis of their ?
A. Density
B. Volume
C. Diameter
D. Cell membrane configuration
3. Which of the following is a Lipoprotein ?
A. Chylomicrons
B. Very low density lipoproteins (VLDL)
C. Low-density lipoproteins (LDL)
D. All of the above
4. Major apolipoprotein of VLDL, IDL, and LDL is ?
A. Apo B100
B. Apo B48
C. Apo E
D. Apo AI
5. Apolipoprotein that is essential for assembly & secretion of chylomicrons is ?
A. Apo B100
B. Apo B48
C. Apo E
D. Apo AI
6. Apolipoprotein that is essential for assembly & secretion of VLDL from liver is ?
A. Apo B100
B. Apo B48
C. Apo E
D. Apo AI
7. Apolipoprotein that is essential activator of enzyme lipoprotein lipase (LPL) is ?
A. Apo B100
B. Apo B48
C. Apo E
D. Apo CII
8. Apo E is synthesized mainly in hepatocytes and also in ?
A. Macrophages
B. Neurons
C. Glial cells
D. All of the above
9. Which of the following Apo A is synthesized only in small intestine ?
A. apo AI
B. apo AII
C. apo AIV
D. All of the above
10. apo AI, apo AII and apo AIV are found primarily on ?
A. HDL
B. LDL
C. VLDL
D. IDL
11. Enzyme lecithin:cholesterol acyltransferase (LCAT) which esterifies free cholesterol in plasma is activated by ?
A. Apo AI
B. Apo AII
C. Apo AIV
D. None of the above
12. Which of the following enzymes are involved in lipoprotein metabolism ?
A. Lipoprotein lipase (LPL)
B. Hepatic triglyceride lipase (HTGL)
C. Cholesteryl ester transfer protein (CETP)
D. All of the above
13. Cholesteryl ester transfer protein (CETP) circulates in plasma in association with ?
A. HDL
B. LDL
C. VLDL
D. Chylomicrons
14. Normolipidemic individuals dispose of most dietary fat in the bloodstream within ?
A. 2 hours of the last meal
B. 4 hours of the last meal
C. 6 hours of the last meal
D. 12 hours of the last meal
15. The surface coat of the chylomicron is composed of ?
A. Phospholipid
B. Free cholesterol
C. apo B48, apo AI, apo AII, and apo AIV
D. All of the above
16. In plasma, apo C proteins are transferred to chylomicron from which lipoprotein ?
A. HDL
B. LDL
C. VLDL
D. IDL
17. The crucial structural apoprotein for HDL is ?
A. Apo AI
B. Apo B48
C. Apo B100
D. Apo E
18. Which of the following represents the initial lesion of atherosclerosis ?
A. Fibrous plaque
B. Intimal thickening
C. Fatty streak
D. Any of the above
19. Among oral hypoglycemic agents, which of the following has the best evidence base for cardiovascular event reduction ?
A. Metformin
B. Sulfonyurea
C. Pioglitazone
D. Acarbose
20. In diabetic populations, American Diabetes Association recommends a blood pressure goal of ?
A. 120/70 mmHg
B. 130/70 mmHg
C. 120/80 mmHg
D. 130/80 mmHg
21. Fredrickson classification is used to classify ?
A. Hyperlipoproteinemia
B. Bile acids
C. Obesity
D. Apolipoproteins
22. Which of the following hyperlipidemias is not characterized by elevated triglycerides ?
A. Type I
B. Type IIa
C. Type IIb
D. Type III