[MCQ] Glomerular Diseases- Part 4

I. Start the exam by click the “Start” button

See all quizzes of Glomerular Diseases at here:

1.Which of the following is called “dense deposit disease” ?
A. Type I membranoproliferative glomerulonephritis
B. Type II Membranoproliferative glomerulonephritis
C. Type III Membranoproliferative glomerulonephritis
D. None of the above


2. Mesangioproliferative glomerulonephritis is seen in ?
A. IgA nephropathy
B. P. falciparum malaria

C. Resolving postinfectious glomerulonephritis
D. All of the above

3.  Minimal change disease (MCD) is also called ?
A. Nil disease
B. Lipoid nephrosis
C. Foot process disease
D. All of the above
4.  Minimal Change Disease (MCD) is associated with ?
A. Hodgkin’s disease
B. Allergies
C. Use of nonsteroidal anti-inflammatory agents
D. All of the above

5.  Minimal Change Disease (MCD) on electron microscopy of renal biopsy consistently shows ?
A. Mesangial proliferation
B. Mesangial interposition
C. Effacement of the foot process
D. All of the above

6.  Which of the following is false about minimal change disease ?
A. Known as nil lesion
B. Commonest cause of nephrotic syndrome in adults
C. Acellular urinary sediment
D. Selective proteinuria

7.  MCD patients with steroid resistance can develop ?
A. Focal segmental glomerulosclerosis (FSGS)
B. Mesangioproliferative glomerulonephritis
C. Microscopic polyangiitis
D. Any of the above

8.  In MCD, relapses occur in what proportion of children after the first remission ?
A. 10 – 20 %
B. 30 – 40 %
C. 50 – 60 %
D. 70 – 75 %

9.  Pathologic changes of focal segmental glomerulosclerosis (FSGS) are most prominent in glomeruli located at ?
A. Corticomedullary junction
B. Outer cortex
C. Middle cortex
D. All of the above

10. What value of protein:creatinine ratio indicates nephrotic range proteinuria ?
A. > 100 – 150 mg/mmol
B. > 200 – 250 mg/mmol
C. > 250 – 300 mg/mmol
D. > 300 – 350 mg/mmol

11.  Majority of children with nephrotic syndrome are due to ?
A. Minimal change disease (MCD)
B. Focal and segmental glomerulosclerosis (FSGS)
C. Membranous glomerulopathy
D. Membranoproliferative glomerulonephritis (MPGN)
12.  Most common cause of nephrotic syndrome in the elderly is ?
A. Minimal Change Disease (MCD)
B. Focal segmental glomerulosclerosis (FSGS)
C. Membranous glomerulonephritis (MGN)
D. Mesangioproliferative glomerulonephritis

13.  Most common cause of nephrotic syndrome in black patients is ?
A. Minimal Change Disease (MCD)
B. Focal segmental glomerulosclerosis (FSGS)
C. Membranous glomerulonephritis (MGN)
D. Mesangioproliferative glomeru2€phritis

14.  Membranous glomerulonephritis (MGN) can be secondary to ?
A. Solid tumors of breast, lung, colon
B. Hepatitis B
C. Malaria
D. All of the above

15. Which of the following causes of nephrotic syndrome has the highest incidences of renal vein thrombosis, pulmonary embolism, and deep vein thrombosis ?
A. Minimal change disease (MCD)
B. Focal segmental glomerulosclerosis (FSGS)
C. Membranous glomerulonephritis (MGN)
D. Diabetic nephropathy

16.  How many years after the onset of clinical diabetes, morphologic changes appear in kidneys ?
A. 1 – 2 years
B. 3 – 4 years
C. 5 – 7 years
D. 7 – 9 years

17.  In Types 1 or 2 diabetes, microalbuminuria appears how many years after the onset of diabetes ?
A. 2 – 5
B. 5 – 10
C. 10 – 15
D. 15 – 20

18.  Which of the following histopathological findings occur in diabetic kidneys ?
A. Thickening of GBM
B. Expansion of mesangial matrix
C. Nodular glomerulosclerosis
D. All of the above
19.  Kimmelstiel-Wilson lesion relates best with which of the following histopathological findings in diabetic kidney ?
A. Thickening of GBM
B. Expansion of mesangial matrix
C. Nodular glomerulosclerosis
D. Hyaline arteriosclerosis

20. Which of the following is different between Types 1 & 2 diabetes ?
A. Natural history of diabetic nephropathy
B. Renal biopsy findings
C. Onset of microalbuminuria
D. Presence of diabetic retinopathy

21.  In microalbuminuria, the range of albuminuria is ?
A. < 150 mg/day
B. 20 – 200 mg/day
C. 30 – 300 mg/day
D. 40 – 400 mg/day

22. Dipstick positive level of albuminuria is ?
A. > 30 mg
B. > 150 mg
C. > 300 mg
D. > 500 mg

23.  In diabetes, renal functions unrelentingly decline after what level of proteinuria ?
A. > 500 mg/day
B. > 1000 mg/day
C. > 1500 mg/day
D. > 2500 mg/day