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Glomerular Diseases- Part 3
See all quizzes of Glomerular Diseases at here:
1.α3 (IV) NC1 peptides are produced by ?
A. Lymph node
B. Bone marrow
C. Spleen
D. Thymus
3. Which of the following is false about Goodpasture’s syndrome ?
A. Occurs in young men in late 20s
B. Occurs in men & women in 60 – 70s
C. Hemoptysis is largely confined to smokers
D. None of the above
4. Antibodies against the 1(IV) NC1 domain is seen in patients with ?
A. Leukemia
B. Paraneoplastic syndrome
C. SLE
D. All of the above
5. In Goodpasture’s syndrome, which of the following indicate worse prognosis at presentation ?
A. Oliguria
B. >50% crescents on renal biopsy
C. Serum creatinine >5.7 mg/dL
D. All of the above
6. Patients of Goodpasture’s syndrome respond to which of the following treatments ?
A. Plasmapheresis
B. Oral prednisone
C. Cyclophosphamide
D. All of the above
7. Which of the following is false about Alport’s syndrome ?
A. Inherited tubulointerstitial disease
B. Due to mutation in COL4A5 gene
C. Hematuria, glomerulosclerosis & renal failure
D. Usually X linked
8. Which of the following is related to Alport’s syndrome ?
A. Ataxia
B. Sensorineural deafness
C. Alopecia
D. Jaundice
8. Positive “oil droplet sign” in Alport’s syndrome pertains to ?
A. Ocular lens
B. Tongue
C. Nails
D. Nose
9. Out of the following, which is the most common form of glomerulonephritis ?
A. IgA nephropathy
B. Focal sclerosing glomerulonephritis
C. Rapidly progressive/crescentic glomerulonephritis
D. Membranous glomerulonephritis
10. IgA nephropathy is also called ?
A. Barratt disease
B. Berger disease
C. Tomino disease
D. Glassock disease
11. Which of the following is false about IgA nephropathy ?
A. Female preponderance
B. Peak incidence in II & III decades of life
C. Recurrent episodes of macroscopic hematuria
D. Between episodes, urinalysis is normal
12. IgA nephropathy resembles which of the following diseases ?
A. Wegener’s granulomatosis
B. Goodpasture’s syndrome
C. Henoch Schonlein purpura
D. All of the above
13. Most IgA deposited in the kidney are derived from ?
A. Lymph node
B. Bone marrow
C. Spleen
D. Liver
14. In IgA nephropathy, deposition of IgA occurs in ?
A. Glomerular capillaries
B. Glomerular mesangium
C. Glomerular basement membrane
D. All of the above
15. Deposits of IgA in glomerular mesangium are found in ?
A. Leprosy
B. Crohn’s disease
C. Chronic liver disease
D. All of the above
16. Deposits of IgA in glomerular mesangium are found in ?
A. Ankylosing spondylitis
B. Idiopathic interstitial pneumonia
C. Sjögren’s syndrome
D. All of the above
.
17. Which of the following is an ANCA-positive, pauci-immune glomerulonephritis ?
A. Wegener’s granulomatosis
B. Microscopic polyangiitis
C. Churg-Strauss syndrome
D. All of the above
18. Wegener’s granulomatosis presenting without renal involvement is termed ?
A. Wegener’s disease
B. Wegener’s syndrome
D. Limited Wegener’s granulomatosis
19. In microscopic polyangiitis, which of the following is uncommon ?
A. Hematuria
B. Proteinuria
C. Significant lung disease or destructive sinusitis
D. Renal involvement
20. Which of the following distinguishes Churg-Strauss Syndrome from other small-vessel vasculitis ?
A. Pulmonary infiltrates
B. Peripheral eosinophilia
C. Glomerulonephritis
D. All of the above
21. Mesangiocapillary glomerulonephritis or lobar glomerulonephritis is also called ?
A. Focal segmental glomerulosclerosis
B. Membranous glomerulonephritis
C. Membranoproliferative glomerulonephritis
D. Mesangioproliferative glomerulonephritis
22. Type I Membranoproliferative glomerulonephritis (MPGN) is associated with ?
A. Persistent hepatitis C infections
B. Lupus
C. Neoplastic diseases
D. All of the above
