[MCQ] Cirrhosis- Part 7

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See all quizzes of Cirrhosis at here:

Cirrhosis- Part 1| Cirrhosis- Part 2| Cirrhosis- Part 3| Cirrhosis- Part 4| Cirrhosis- Part 5| Cirrhosis- Part 6| Cirrhosis- Part 7| Cirrhosis- Part 8

1.Factors leading to worsening ascites include all except ?
A. Excessive salt intake
B. Medication noncompliance
C. Superimposed infection
D. GI bleed
2. Factors leading to worsening ascites include all except ?
A. Worsening liver disease
B. Portal vein thrombosis
C. Splenic vein thrombosis
D. Development of hepatocellular carcinoma
3. In cirrhosis liver with ascites, response to salt restriction alone
is more likely to occur if ?
A. Ascites is of recent onset
B. Underlying liver disease is reversible
C. Precipitating factor can be corrected
D. All of the above
4. In cirrhosis liver with ascites, response to salt restriction alone
is more likely to occur if ?
A. High urinary sodium excretion (>25 mmol/day)
B. Normal renal function
C. Ascites is of recent onset
D. All of the above
5. Which of the following statements about spontaneous bacterial
peritonitis (SBP) is false ?
A. Develops without obvious primary source of infection
B. Ascitic fluid has high concentrations of albumin
C. In ascitic fluid, >250 PMN/μL is diagnostic
D. Monomicrobial nonneutrocytic bacterascites is a variant of SBP

6. Which of the following statements about spontaneous bacterial
peritonitis (SBP) is false ?
A. Escherichia coli are most commonly isolated

B. A single organism is typically isolated
C. Anaerobes are found less frequently
D. Recurrent episodes are relatively uncommon

7. Which of the following statements about spontaneous bacterial
peritonitis (SBP) is false ?
A. Therapy is for 10 to 14 days
B. Prophylactic norfloxacin reduces recurrences
C. Primary prevention recommended in high-risk cirrhotics
D. Empirical coverage for anaerobes is necessary

8. Hepatorenal syndrome (HRS) occurs in what percentage of
patients with advanced cirrhosis or acute liver failure ?
A. ~ 5 %
B. ~ 10 %
C. ~ 20 %
D. ~ 30 %

9. Which of the following about hepatorenal syndrome is false ?
A. Splanchnic vasodilation
B. Arteriovenous shunting
C. Profound renal vasoconstriction
D. None of the above

10. Renal failure in cirrhosis is defined as serum creatinine above
?
A. 1.2 mg /dL
B. 1.3 mg /dL
C. 1.4 mg /dL
D. 1.5 mg /dL

11. Which of the following about hepatorenal syndrome is false ?
A. Type I HRS is the more aggressive form
B. Type I HRS carries a mortality rate of >90%
C. HRS is seen in patients with refractory ascites
D. None of the above

12. Type 1 HRS is characterized by doubling of serum creatinine
level to > 2.5 mg/dl in ?
A. < 2 weeks
B. < 4 weeks
C. < 6 weeks
D. < 8 weeks

13. Which of the following is true for type 1 hepatorenal syndrome ?
A. Progressive oliguria
B. Rapid rise of serum creatinine
C. Common precipitating event is SBP
D. All of the above

14. Which of the following is true for type 2 hepatorenal syndrome ?
A. Most have refractory ascites
B. Increase in serum creatinine is moderate
C. No tendency of serum creatinine to progress over time
D. All of the above

15. Type 2 HRS is mainly characterized by ?
A. Hepatic encephalopathy
B. Refractory ascites
C. Hypotension
D. All of the above

16.  Which of the following treatments have a role in hepatorenal
syndrome ?
A. Midodrine
B. Octreotide
C. Intravenous albumin
D. All of the above

17. Which of the following is a vasoconstrictor drug ?
A. Terlipressin
B. Norepinephrine
C. Midodrine
D. All of the above

18. Long-term administration of which of the following reduces
the risk of hepatorenal syndrome & improves survival ?
A. Norfloxacin
B. Eplerenone
C. Toresamide
D. Vitamin E
19. Which of the following statements about hepatorenal syndrome
(HRS) is false ?
A. Worsening azotemia
B. Avid sodium retention
C. Oliguria without identifiable causes of renal dysfunction
D. Kidneys are structurally smaller
20. Which of the following statements about hepatorenal syndrome
(HRS) is false ?
A. Urinalysis normal
B. Renal biopsy is normal
C. Kidneys can be used for renal transplantation
D. Hypernatremia
21. Which of the following statements about hepatorenal syndrome
(HRS) is false ?
A. Treatment is usually unsuccessful
B. Vasodilator therapy with intravenous infusions of low dose
dopamine is effective
C. TIPS can improve renal function
D. Treatment of choice is liver transplantation
22. Which of the following is false about hepatic encephalopathy ?
A. More common in chronic liver disease
B. Essential for diagnosis of fulminant hepatic failure
C. Diagnosis of hepatic encephalopathy is clinical
D. None of the above
23. Which of the following charactetistics about hepatic
encephalopathy is false ?
A. Disturbances in consciousness
B. Behavior & personality changes
C. Fluctuating neurologic signs
D. No electroencephalographic changes
24. Which of the following statements about hepatic
encephalopathy is false ?
A. Blood-brain barrier is intact
B. Ammonia is incriminated in its pathogenesis
C. Many patients have elevated blood ammonia levels
D. Mercaptans, short-chain fatty acids, & phenol are
incriminated in its pathogenesis

25.Which of the following statements about hepatic
encephalopathy is false ?
A. Reduced levels of consciousness is due to excessive
concentrations of GABA in the CNS
B. Endogenous benzodiazepines act through the GABA receptor
C. 1,4-benzodiazepines is isolated from brain tissue of patients
with fulminant hepatic failure
D. Excessive magnesium deposition in basal ganglia contribute
its pathogenesis