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Toxic and drug-induced hepatitis Part 2
See all quizzes of Acute viral hepatitis at here:
1. Which of the following anticonvulsant agent is not a CYP3A
Inducer ?
A. Carbamazepine
B. Phenobarbital
C. Phenytoin
D. Lamotrigine
2.Major hepatic isoenzyme involved in warfarin metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
3. Major hepatic isoenzyme involved in phenytoin metabolism
is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
4.Major hepatic isoenzyme in omeprazole metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
5. Major hepatic isoenzyme in metoprolol metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
6. Major hepatic isoenzyme in tricyclic antidepressants
metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
7. Major hepatic isoenzyme involved in selective serotonin
reuptake inhibitors metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
8. Major hepatic isoenzyme involved in codeine metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
9.Major hepatic isoenzyme in cyclosporine metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
10.Major hepatic isoenzyme in statin metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
11. Major hepatic isoenzyme in phenytoin metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
12.Major hepatic isoenzyme in lidocaine metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
13.Major hepatic isoenzyme in quinidine metabolism is ?
A. CYP 2C9
B. CYP 2C19
C. CYP 2D6
D. CYP 3A
14. CYP enzyme activity inducers include ?
A. Phenobarbital
B. Rifampin
C. Carbamazepine
D. All of the above
15. CYP enzyme activity inducers include ?
A. Phenytoin
B. Smoking
C. Chronic alcohol ingestion
D. All of the above
16. CYP enzyme activity inducers lower plasma levels of which of
the following drugs ?
A. Warfarin
B. Quinidine
C. Mexiletine
D. All of the above
17. CYP enzyme activity inducers lower plasma levels of which of
the following drugs ?
A. Verapamil
B. Ketoconazole
C. Itraconazole
D. All of the above
18. CYP enzyme activity inducers lower plasma levels of which of
the following drugs ?
A. Cyclosporine
B. Dexamethasone
C. Methylprednisolone
D. All of the above
19. CYP enzyme activity inducers lower plasma levels of which of
the following drugs ?
A. Oral contraceptive steroids
B. Methadone
C. Metronidazole
D. All of the above
20. Which of the following drugs is associated with moderate to
severe chronic hepatitis ?
A. Oxyphenisatin
B. Methyldopa
C. Isoniazid
D. All of the above
21. Which of the following drugs is implicated in the development
of cirrhosis ?
A. Oxyphenisatin
B. Methyldopa
C. Isoniazid
D. Halothane
22. Syndrome resembling primary biliary cirrhosis can occur
following treatment with ?
A. Chlorpromazine
B. Methyl testosterone
C. Tolbutamide
D. All of the above
23. Portal hypertension in the absence of cirrhosis may result from
the use of ?
A. Vitamin A
B. Arsenic intoxication
C. Exposure to vinyl chloride
D. All of the above
