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Seizures and Epilepsy- Part 6
See all quizzes of Seizures and Epilepsy at here:
Seizures and Epilepsy- Part 1| Seizures and Epilepsy- Part 2| Seizures and Epilepsy- Part 3| Seizures and Epilepsy- Part 4| Seizures and Epilepsy- Part 5| Seizures and Epilepsy- Part 6
1 Which of the following is the first-line medication in typical absence
seizures ?
A. Valproic acid
B. Lamotrigine
C. Carbamazepine
D. Ethosuximide
2 Which of the following is the first-line medication in atypical
absence seizures ?
A. Valproic acid
B. Lamotrigine
C. Carbamazepine
D. Ethosuximide
3 Which of the following is the first-line medication in myoclonic
seizures ?
A. Valproic acid
B. Lamotrigine
C. Carbamazepine
D. Ethosuximide
4 Which of the following is not a first-line medication in seizures ?
A. Valproic acid
B. Lamotrigine
C. Carbamazepine
D. Gabapentin
5 Which of the following anti-epileptic drugs is preferred in Lennox-
Gastaut syndrome ?
A. Phenobarbital
B. Valproic acid
C. Gabapentin
D. Lamotrigine
.
6 Which of the following anti-epileptic drugs does not have
significant drug interactions ?
A. Phenobarbital
B. Valproic acid
C. Gabapentin
D. Lamotrigine
7 Most recurrences of epilepsy occur how many months after
discontinuing therapy ?
A. 3 months
B. 4 months
C. 5 months
D. 6 months
8 Which of the following anti-epileptic medications have enzymeinducing
effects ?
A. Phenytoin
B. Phenobarbital
C. Primidone
D. All of the above
9 Carbamazepine and phenytoin are contraindicated in which of
the following epilepsies ?
A. Juvenile myoclonic epilepsy (JME)
B. Absence seizures
C. Myoclonic seizures
D. All of the above
10 Which of the following is the adverse effect of carbamazepine ?
A. Leukopenia
B. Aplastic anemia
C. Hepatotoxicity
D. All of the above
11 Treatment of choice for juvenile myoclonic epilepsy is ?
A. Valproic acid
B. Lamotrigine
C. Acetazolamide
D. Topiramate
12 Which of the following anti-epileptic medications rarely cause
skin rashes ?
A. Gabapentin
B. Divalproex sodium
C. Levetiracetam
D. All of the above
13 Which of the following anti-epileptic drug causes skin rashes ?
A. Gabapentin
B. Divalproex sodium
C. Levetiracetam
D. Lamotrigine
14 What percentage of patients with epilepsy do not respond to
treatment with a single antiepileptic drug ?
A. ~ one-fourth
B. ~ one-third
C. ~ one-half
D. ~ two-third
15 Most common surgical procedure for patients with temporal lobe
epilepsy involves resection of ?
A. Anteromedial temporal lobe
B. Anterolateral temporal lobe
C. Posteromedial temporal lobe
D. Posterolateral temporal lobe
16 During pregnancy, seizure frequency decreases in what percentage
of women ?
A. 10 %
B. 20 %
C. 30 %
D. 40 %
17 Which of the following anti-epileptic medications can significantly
antagonize effects of oral contraceptives ?
A. Carbamazepine
B. Phenytoin
C. Topiramate
D. All of the above
18 Ratio of drug concentration in breast milk relative to serum is
maximum with which of the following antiepileptic drug ?
A. Ethosuximide
B. Phenobarbital
C. Carbamazepine
D. Phenytoin
19 Ratio of drug concentration in breast milk relative to serum is
minimum with which of the following antiepileptic drug ?
A. Valproic acid
B. Phenobarbital
C. Carbamazepine
D. Phenytoin
20 One of the most specific signs of a metabolic encephalopathy is ?
A. Bilateral Asterixis
B. Confusion
C. Seizure
D. Vomiting
21 Asterixis can be found in ?
A. Any tonically held posture
B. Tonically held tongue
C. Voluntary limb motion
D. All of the above
22 In an awake patient of uremic encephalopathy, the typical
movement abnormality is ?
A. Myoclonic jerking and tremor
B. Partial seizure
C. Primary generalized seizure
D. Absence seizure
23 Typical movement abnormality seen with use of antipsychotic
drugs such as lithium, phenothiazines, or butyrophenones is ?
A. Myoclonic jerking and tremor
B. Partial seizure
C. Primary generalized seizure
D. Absence seizure
24 Which of the following statements about status epilepticus is
false ?
A. Continuous seizures
B. Repetitive, discrete seizures
C. Impaired consciousness in the interictal period
D. May be nonconvulsive
25 In generalized convulsive status epilepticus (GCSE), which of the
following leads to irreversible neuronal injury ?
A. Cardiorespiratory dysfunction
B. Hyperthermia
C. Metabolic derangements
D. All of the above
24 Which of the following is the first medicine that is recommended
for generalized tonic-clonic status epilepticus in adults?
A. Lorazepam
B. Fosphenytoin
C. Valproate
D. Phenobarbital
25 Which of the following is the effect of selective serotonin reuptake
inhibitors (SSRIs) on seizures ?
A. Increase seizure frequency
B. Decrease seizure frequency
C. No effect
D. Any of the above
26 Which of the following is false about “Sudden unexpected death
in epileptic patients (SUDEP) ?
A. Affects young people with convulsive seizures
B. Tends to occur at night
C. May result from brainstem-mediated effects of seizures on
cardiac rhythms or pulmonary function
