The quizzes about Aplastic and Related Anemias

1. Acquired aplastic anemia may be caused by
A. benzene or benzene derivatives
B. ionizing radiation and vitamin B12
C. purine or pyrimidine analogues
D. all of the above

2. The sudden appearance of aplastic anemia or pure red cell aplasia is often caused by
A. a hemolytic process
B. an immune process
C. acute leukemias
D. chronic leukemias

3. Aplastic anemia can occur years before a diagnosis of _____ is made.
A. paroxysmal nocturnal hemoglobinuria
B. myelodysplasia
C. acute myelogenous leukemia
D. all of the above

4. If a patient with aplastic anemia is referred to as exhibiting pancytopenia, which cell lines are affected?
A. Erythrocytes
B. Leukocytes
C. Thrombocytes
D. All of the above

5. _____ Fanconi anemia

A. A subset of Fanconi anemia
B. A rare congenital form of red cell aplasia
C. Is characterized by selective failure of red blood cell production
D. The best-described congenital form of aplastic anemia

6. _____ Familial aplastic anemia

A. A subset of Fanconi anemia
B. A rare congenital form of red cell aplasia
C. Is characterized by selective failure of red blood cell production
D. The best-described congenital form of aplastic anemia

7. _____ Pure red cell anemia

A. A subset of Fanconi anemia
B. A rare congenital form of red cell aplasia
C. Is characterized by selective failure of red blood cell production
D. The best-described congenital form of aplastic anemia

8. _____ Diamond-Blackfan syndrome

A. A subset of Fanconi anemia
B. A rare congenital form of red cell aplasia
C. Is characterized by selective failure of red blood cell production
D. The best-described congenital form of aplastic anemia

9. Hematopoietic cell targets in aplastic anemia are affected by
A. activated cytotoxic T lymphocytes
B. activation of the Fas receptor
C. direct cell–cell interactions between lymphocytes and target cells
D. all of the above

10. Fanconi anemia is associated with abnormal genes located on chromosomes __q___, __q___.
A. 9, 20
B. 5, 22
C. 9, 12
D. 8, 23