The Immunology and Allergy quizzes – part 2

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The Immunology and Allergy quizzes – part 2
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Select the ONE answer that is BEST in each case.

A 23-year-old man has a reaction after being given oral penicillin for a sore throat.

Penicillin can cause numerous allergic reactions, including anaphylaxis, interstitial nephritis, rashes (the most common manifestation), urticaria, fever, pneumonitis, dermatitis, and even asthma in workers exposed to airborne penicillin. Hemolytic anemia is often IgGmediated. Skin tests are reliable in predicting low risk (similar to general population) for those claiming previous penicillin reactions, and desensitization is feasible. The frequency of reactions to cephalosporins in penicillinallergic patients is not definitely known.

 

See all quizzes of  the Immunology and Allergy at here:

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21. A 23-year-old man has a reaction after being given oral penicillin for a sore throat.

(A) allergic reaction caused by sensitized mast cells
(B) may be mediated by drug effect on kinin system
(C) final mediator of symptoms are leukotrienes

22. A 56-year-old woman is given an angiotensinconverting enzyme (ACE) inhibitor for control of hypertension and develops a reaction consisting of urticaria.

(A) allergic reaction caused by sensitized mast cells
(B) may be mediated by drug effect on kinin system
(C) final mediator of symptoms are leukotrienes

23. A 23-year-old man has an exacerbation of asthma when he takes aspirin for a headache.

(A) allergic reaction caused by sensitized mast cells
(B) may be mediated by drug effect on kinin system
(C) final mediator of symptoms are leukotrienes

24. A 29-year-old man presents with severe back pain and a red eye. The pain is located in his lower back and gluteal area, and is associated with morning stiffness that improves after several hours. On examination, he has limited forward flexion and tenderness of the ischial tuberosities.

(A) human lymphocyte antigen (HLA) B27
(B) HLA DR4
(C) HLA DR3
(D) HLA B17
(E) HLA B8
(F) multigenic disorder

25. A 24-year-old woman has a facial skin lesion, thrombocytopenia, arthralgia, and pericarditis.

(A) human lymphocyte antigen (HLA) B27
(B) HLA DR4
(C) HLA DR3
(D) HLA B17
(E) HLA B8
(F) multigenic disorder

26. A 12-year-old child has severe deforming arthritis of the hands.

(A) human lymphocyte antigen (HLA) B27
(B) HLA DR4
(C) HLA DR3
(D) HLA B17
(E) HLA B8
(F) multigenic disorder

27. A 14-year-old girl presents with weight loss, increased thirst, and urination. Her laboratory tests reveal hyperglycemia and a mildly increased anion gap metabolic acidosis.

(A) human lymphocyte antigen (HLA) B27
(B) HLA DR4
(C) HLA DR3
(D) HLA B17
(E) HLA B8
(F) multigenic disorder

28. A 22-year-old man with iritis, balanitis, urethritis, and arthritis.

(A) human lymphocyte antigen (HLA) B27
(B) HLA DR4
(C) HLA DR3
(D) HLA B17
(E) HLA B8
(F) multigenic disorder

29. A 27-year-old woman has severe symmetrical small joint arthritis. She notices 1 hour of morning stiffness and swelling with redness in her wrists and hand joints. The distal finger joints are spared. X-rays of the hands reveal early bone erosion in some of the joints.

(A) human lymphocyte antigen (HLA) B27
(B) HLA DR4
(C) HLA DR3
(D) HLA B17
(E) HLA B8
(F) multigenic disorder

30. A 33-year-old policeman develops acute asymmetric arthritis involving his left knee and ankle and right ankle. The pain in the feet prevents him from walking. He recalls having a diarrheal illness 3 weeks ago.

(A) human lymphocyte antigen (HLA) B27
(B) HLA DR4
(C) HLA DR3
(D) HLA B17
(E) HLA B8
(F) multigenic disorder

31. A 73-year-old man has a history of recurrent pneumonias. He now complains of bone discomfort in his back and chest. X-rays reveal multiple lytic lesions and his serum protein electrophoresis has an IgG spike of 12 g/dL.

(A) B-cell deficiency/dysfunction
(B) mixed T- and B-cell deficiency/
dysfunction
(C) T-lymphocyte deficiency/dysfunction
(D) neutropenia
(E) chemotaxis
(F) C3 (complement 3) deficiency

32. A 22-year-old woman notices multiple lymph nodes in her neck. They are nontender on palpation and mobile. A monospot test is negative and a biopsy of the node reveals Hodgkin’s disease.

(A) B-cell deficiency/dysfunction
(B) mixed T- and B-cell deficiency/ dysfunction
(C) T-lymphocyte deficiency/dysfunction
(D) neutropenia
(E) chemotaxis
(F) C3 (complement 3) deficiency

33. A 73-year-old man has 30,000/mL mature lymphocytes on his blood film. This is an incidental finding and he is clinically feeling well.

(A) B-cell deficiency/dysfunction
(B) mixed T- and B-cell deficiency/
dysfunction
(C) T-lymphocyte deficiency/dysfunction
(D) neutropenia
(E) chemotaxis
(F) C3 (complement 3) deficiency

34. A 24-year-old woman with malar rash, thrombocytopenia, and arthralgia.

(A) B-cell deficiency/dysfunction
(B) mixed T- and B-cell deficiency/ dysfunction
(C) T-lymphocyte deficiency/dysfunction
(D) neutropenia
(E) chemotaxis
(F) C3 (complement 3) deficiency

35. A 69-year-old man is receiving chemotherapy for acute myeloid leukemia.

(A) B-cell deficiency/dysfunction
(B) mixed T- and B-cell deficiency/ dysfunction
(C) T-lymphocyte deficiency/dysfunction
(D) neutropenia
(E) chemotaxis
(F) C3 (complement 3) deficiency

36. A young woman with ataxia-telangiectasia syndrome.

(A) B-cell deficiency/dysfunction
(B) mixed T- and B-cell deficiency/ dysfunction
(C) T-lymphocyte deficiency/dysfunction
(D) neutropenia
(E) chemotaxis
(F) C3 (complement 3) deficiency

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