[MCQ]The Female Reproductive System, Infertility, and Contraception- Part 2

I. Start the exam by click the “Start” button

The Female Reproductive System, Infertility, and Contraception- Part 2

Please wait while the activity loads.
If this activity does not load, try refreshing your browser. Also, this page requires javascript. Please visit using a browser with javascript enabled.

If loading fails, click here to try again

Start

Congratulations - you have completed The Female Reproductive System, Infertility, and Contraception- Part 2. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rated as %%RATING%%

Your answers are highlighted below.

Question 1

Which of the following contributes to endothelial dysfunction, hypertension, and proteinuria in preeclampsia ?

A	fms-like tyrosine kinase 1
B	fms-like tyrosine kinase 2
C	fms-like tyrosine kinase 3
D	fms-like tyrosine kinase 4

Question 1 Explanation:

Excessive placental secretion of a soluble fms-like tyrosine kinase 1, a naturally occurring vascular endothelial growth factor antagonist, and decreased secretion of placental growth factor may contribute to endothelial dysfunction, hypertension & proteinuria observed in preeclampsia.

Question 2

Stroke in preeclampsia may occur at ?

A	Sub-normal blood pressures
B	Near-normal blood pressures
C	Hypertension range blood pressures
D	Any of the above

Question 2 Explanation:

Preeclampsia is associated with abnormalities of cerebral circulatory autoregulation, which increase the risk of stroke at near-normal blood pressures.

Question 3

Risk factors for development of preeclampsia include all except ?

A	Multiparity
B	Diabetes mellitus
C	History of renal disease
D	Chronic hypertension

Question 4

Risk factors for development of preeclampsia include all except ?

A	Prior history of preeclampsia
B	Extremes of maternal age (>35 years or <15 years)
C	Low BMI
D	Factor V Leiden mutation

Question 5

Risk factor for development of preeclampsia is ?

A	Angiotensinogen gene T235
B	Antiphospholipid antibody syndrome
C	Multiple gestation
D	All of the above

Question 5 Explanation:

Risk factors for the development of preeclampsia include nulliparity, diabetes mellitus, a history of renal disease or chronic hypertension, prior history of preeclampsia, extremes of maternal age (>35 years or <15 years), obesity, factor V Leiden mutation, angiotensinogen gene T235, G20210A prothrombin gene mutation, antiphospholipid antibody syndrome & multiple gestation.

Question 6

To define severe preeclampsia, which of the following is false ?

A	New-onset hypertension
B	Severe proteinuria
C	Central nervous system dysfunction
D	None of the above

Question 7

For the diagnosis of “severe preeclampsia”, the blood pressure must be above ?

A	120 / 80 mmHg
B	130 / 90 mmHg
C	140 / 100 mmHg
D	160 / 110 mmHg

Question 7 Explanation:

Severe preeclampsia is the presence of new-onset hypertension and proteinuria accompanied by CNS dysfunction (headaches, blurred vision, seizures, coma), marked elevations of BP (>160/110 mmHg), severe proteinuria (>5 g/day), oliguria or renal failure, pulmonary edema, hepatocellular injury (ALT > 2 x the upper limits of normal), thrombocytopenia (platelet count < 100,000/L), or disseminated intravascular coagulation.

Question 8

In HELLP syndrome, “H” stands for ?

A	Hemolysis
B	Hemorrhage
C	Hepatitis
D	Hypertension

Question 8 Explanation:

HELLP (hemolysis, elevated liver enzymes, low platelets) syndrome is a special subgroup of severe preeclampsia which increases morbidity & mortality. Presence of platelet dysfunction & coagulation disorders further increases the risk of stroke.

Question 9

For women with severe preeclampsia, delivery is recommended after how many weeks of gestation ?

A	28 weeks
B	32 weeks
C	36 weeks
D	Any of the above

Question 9 Explanation:

Definitive treatment of preeclampsia is delivery of fetus & placenta. For pregnant women with preeclampsia before 37 weeks’ gestation, delivery reduces mother’s morbidity but exposes fetus to risk of premature delivery.

Question 10

Drug that can be used to manage hypertension in severe preeclampsia is ?

A	Labetalol
B	Hydralazine
C	Calcium channel blocker
D	Any of the above

Question 10 Explanation:

Aggressive management of blood pressures > 160/110 mmHg in severe preeclampsia reduces the risk of cerebrovascular accidents. IV labetalol or hydralazine and calcium channel blockers are drugs most commonly used. Raised BP should be reduced slowly to avoid hypotension & a decrease in blood flow to fetus. Angiotensin-converting enzyme (ACE) inhibitors as well as angiotensinreceptor blockers should be avoided in the second and third trimesters of pregnancy because of their adverse effects on fetal development.

Question 11

Drug of choice for prevention & treatment of eclamptic seizures is ?

A	Labetalol
B	Hydralazine
C	Calcium channel blocker
D	Magnesium sulfate

Question 11 Explanation:

Magnesium sulfate is better than phenytoin & diazepam and is the treatment of choice for prevention & treatment of eclamptic seizures.

Question 12

Magnesium prevents seizures by interacting with which of the following in central nervous system ?

A	GABA receptors
B	Glutamate receptors
C	N-methyl-D-aspartate (NMDA) receptors
D	Dopamine receptors

Question 12 Explanation:

Magnesium prevents seizures by interacting with N-methyl-D-aspartate (NMDA) receptors in CNS.

Question 13

Pregnant women with chronic hypertension are at increased risk for all except ?

A	Intrauterine growth restriction
B	Superimposed preeclampsia
C	Abruptio placenta
D	Post partum hemorrhage

Question 13 Explanation:

Pregnancy complicated by chronic essential hypertension is associated with intrauterine growth restriction, increased perinatal mortality, superimposed preeclampsia & abruptio placenta.

Question 14

Which of the following drugs is most commonly used for treatment of chronic hypertension in pregnancy ?

A	Hydralazine
B	Labetalol
C	Beta blocker
D	Diuretic

Question 14 Explanation:

Alpha methyldopa, labetalol & nifedipine are the most commonly used medications for the treatment of chronic hypertension in pregnancy.

Question 15

What percentage of all aortic dissections in women under 40 years of age occur during pregnancy ?

A	About 25 %
B	About 33 %
C	About 50 %
D	About 75 %

Question 16

In “Gestational Hypertension”, the blood pressure is elevated during which trimester of pregnancy ?

A	First
B	Second
C	Third
D	Any time during pregnancy

Question 16 Explanation:

This is the development of elevated blood pressure during pregnancy or in the first 24 hours post partum in the absence of preexisting chronic hypertension and other signs of preeclampsia

Question 17

Valvular disease most likely to cause death during pregnancy is ?

A	Mitral stenosis
B	Mitral regurgitation
C	Aortic stenosis
D	Aortic regurgitation

Question 17 Explanation:

Mitral stenosis is the valvular disease most likely to cause death during pregnancy. Mitral regurgitation, aortic regurgitation & stenosis are well tolerated during pregnancy.

Question 18

In pregnant women, DVT occurs much more commonly in ?

A	Left leg
B	Right leg
C	Left arm
D	Right arm

Question 18 Explanation:

In pregnant women, DVT occurs more commonly in left leg than in right leg, due to compression of left iliac vein by iliac artery and the uterus.

Question 19

Genetic mutations associated with DVT during pregnancy include ?

A	Factor V Leiden mutation
B	Prothrombin G20210A mutation (hetero- & homozygotes)
C	Methylenetetrahydrofolate reductase C677T mutation (homozygotes)
D	All of the above

Question 19 Explanation:

Activated protein C resistance caused by factor V Leiden mutation increases risk of DVT, pulmonary embolism & severe preeclampsia during pregnancy. Prothrombin G20210A mutation (heterozygotes & homozygotes) & methylenetetrahydrofolate reductase C677T mutation (homozygotes) also increases risk of DVT.

Question 20

Which of the following is false for women with artificial valves contemplating pregnancy ?

A	Warfarin be stopped & heparin initiated prior to conception
B	Prophylaxis against thrombosis with low-molecular-weight heparin (LMWH) is not recommended
C	Prophylaxis with unfractionated heparin is recommended
D	None of the above

Question 21

Warfarin therapy during the first trimester of pregnancy is associated with ?

A	Fetal chondrodysplasia punctata
B	Fetal optic atrophy
C	Mental retardation
D	All of the above

Question 21 Explanation:

Warfarin therapy is contraindicated in the 1st trimester due to its association with fetal chondrodysplasia punctata. In 2nd & 3rd trimesters, warfarin may cause fetal optic atrophy and mental retardation.

Question 22

Which of the following about DVT in pregnancy is false ?

A	LMWH or unfractionated heparin can be used for anticoagulation
B	Warfarin therapy is contraindicated
C	Warfarin is contraindicated in breast-feeding women
D	DVT can occur in postpartum period

Question 22 Explanation:

Warfarin is not contraindicated in breast-feeding women. During pregnancy, warfarin is teratogenic & should be avoided.

Question 23

When DVT occurs in the postpartum period, warfarin is given for ?

A	1 - 3 months
B	3 - 6 months
C	6 - 9 months
D	9 - 12 months

Question 23 Explanation:

When DVT occurs in the postpartum period, LMWH therapy for 7 - 10 days may be followed by warfarin therapy for 3 - 6 months.

Question 24

Which of the following is false in pregnancy ?

A	Fasting plasma glucose is lower by 15 - 20 mg/dL
B	Fasting plasma hydroxybutyrate higher
C	Fasting plasma acetoacetate higher
D	None of the above

Question 24 Explanation:

Pregnancy is a state of accelerated starvation & ketosis. In pregnancy, fasting plasma glucose is lower by 15 - 20 mg/dL than in nonpregnant state due to use of glucose by fetus. Plasma hydroxybutyrate & acetoacetate levels may rise to 2 - 4 times the normal after a fast.

Question 25

During pregnancy, maternal insulin resistance is due to ?

A	Placental production of steroids
B	Placental production of a growth hormone variant
C	Placental production of placental lactogen
D	All of the above

Question 25 Explanation:

Metabolic changes in pregnancy includes maternal insulin resistance caused by placental steroid production, growth hormone variant & placental lactogen.

Once you are finished, click the button below. Any items you have not completed will be marked incorrect. Get Results

There are 25 questions to complete.

←

List

→

Return

Shaded items are complete.

1	2	3	4	5
6	7	8	9	10
11	12	13	14	15
16	17	18	19	20
21	22	23	24	25
End

Return

See all quizzes of The Female Reproductive System, Infertility, and Contraception at here:

1 Which of the following contributes to endothelial dysfunction,
hypertension, and proteinuria in preeclampsia ?
A. fms-like tyrosine kinase 1
B. fms-like tyrosine kinase 2
C. fms-like tyrosine kinase 3
D. fms-like tyrosine kinase 4

2 Stroke in preeclampsia may occur at ?
A. Sub-normal blood pressures
B. Near-normal blood pressures
C. Hypertension range blood pressures
D. Any of the above

3 Risk factors for development of preeclampsia include all except ?
A. Multiparity
B. Diabetes mellitus
C. History of renal disease
D. Chronic hypertension
4 Risk factors for development of preeclampsia include all except ?
A. Prior history of preeclampsia
B. Extremes of maternal age (>35 years or <15 years)
C. Low BMI
D. Factor V Leiden mutation
5 Risk factor for development of preeclampsia is ?
A. Angiotensinogen gene T235
B. Antiphospholipid antibody syndrome
C. Multiple gestation
D. All of the above

6 To define severe preeclampsia, which of the following is false ?
A. New-onset hypertension
B. Severe proteinuria
C. Central nervous system dysfunction
D. None of the above
7 For the diagnosis of “severe preeclampsia”, the blood pressure
must be above ?
A. 120 / 80 mmHg
B. 130 / 90 mmHg
C. 140 / 100 mmHg
D. 160 / 110 mmHg

8 In HELLP syndrome, “H” stands for ?
A. Hemolysis
B. Hemorrhage
C. Hepatitis
D. Hypertension

9 For women with severe preeclampsia, delivery is recommended
after how many weeks of gestation ?
A. 28 weeks
B. 32 weeks
C. 36 weeks
D. Any of the above

10 Drug that can be used to manage hypertension in severe
preeclampsia is ?
A. Labetalol
B. Hydralazine
C. Calcium channel blocker
D. Any of the above

11 Drug of choice for prevention & treatment of eclamptic seizures
is ?
A. Labetalol
B. Hydralazine
C. Calcium channel blocker
D. Magnesium sulfate

12 Magnesium prevents seizures by interacting with which of the
following in central nervous system ?
A. GABA receptors
B. Glutamate receptors
C. N-methyl-D-aspartate (NMDA) receptors
D. Dopamine receptors

13 Pregnant women with chronic hypertension are at increased risk
for all except ?
A. Intrauterine growth restriction
B. Superimposed preeclampsia
C. Abruptio placenta
D. Post partum hemorrhage

14 Which of the following drugs is most commonly used for treatment
of chronic hypertension in pregnancy ?
A. Hydralazine
B. Labetalol
C. Beta blocker
D. Diuretic

15 What percentage of all aortic dissections in women under 40
years of age occur during pregnancy ?
A. About 25 %
B. About 33 %
C. About 50 %
D. About 75 %
16 In “Gestational Hypertension”, the blood pressure is elevated
during which trimester of pregnancy ?
A. First
B. Second
C. Third
D. Any time during pregnancy

17 Valvular disease most likely to cause death during pregnancy is ?
A. Mitral stenosis
B. Mitral regurgitation
C. Aortic stenosis
D. Aortic regurgitation

18 In pregnant women, DVT occurs much more commonly in ?
A. Left leg
B. Right leg
C. Left arm
D. Right arm

19 Genetic mutations associated with DVT during pregnancy include ?
A. Factor V Leiden mutation
B. Prothrombin G20210A mutation (hetero- & homozygotes)
C. Methylenetetrahydrofolate reductase C677T mutation
(homozygotes)
D. All of the above

20 Which of the following is false for women with artificial valves
contemplating pregnancy ?
A. Warfarin be stopped & heparin initiated prior to conception
B. Prophylaxis against thrombosis with low-molecular-weight
heparin (LMWH) is not recommended
C. Prophylaxis with unfractionated heparin is recommended
D. None of the above
21 Warfarin therapy during the first trimester of pregnancy is
associated with ?
A. Fetal chondrodysplasia punctata
B. Fetal optic atrophy
C. Mental retardation
D. All of the above

22 Which of the following about DVT in pregnancy is false ?
A. LMWH or unfractionated heparin can be used for anticoagulation
B. Warfarin therapy is contraindicated
C. Warfarin is contraindicated in breast-feeding women
D. DVT can occur in postpartum period
Warfarin is not contraindicated in breast-feeding women. During pregnancy, warfarin is teratogenic
& should be avoided.
23 When DVT occurs in the postpartum period, warfarin is given
for ?
A. 1 – 3 months
B. 3 – 6 months
C. 6 – 9 months
D. 9 – 12 months

24 Which of the following is false in pregnancy ?
A. Fasting plasma glucose is lower by 15 – 20 mg/dL
B. Fasting plasma hydroxybutyrate higher
C. Fasting plasma acetoacetate higher
D. None of the above

25 During pregnancy, maternal insulin resistance is due to ?
A. Placental production of steroids
B. Placental production of a growth hormone variant
C. Placental production of placental lactogen
D. All of the above

[MCQ]The Female Reproductive System, Infertility, and Contraception- Part 2

I. Start the exam by click the “Start” button

The Female Reproductive System, Infertility, and Contraception- Part 2

Share this:

Related

[MCQ]The Female Reproductive System, Infertility, and Contraception- Part 1

[MCQ]The Female Reproductive System, Infertility, and Contraception- Part 3

You may also like

Leave a Comment Cancel Reply