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The Female Reproductive System, Infertility, and Contraception-Part 10
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1 Which of the following is not a feature of ovary in PCOD ?
A. Sclerotic ovary
B. Multiple follicular cysts
C. Hyperplastic theca and stroma
D. Presence of corpora albicans
2 Anovulatory cycles in PCOD may cause ?
A. Oligomenorrhea or amenorrhea
B. Dysfunctional uterine bleeding
C. Decreased fertility
D. All of the above
3 Cutaneous manifestations of hyperandrogenemia in polycystic
ovary syndrome include all except ?
A. Hirsutism
B. Acne
C. Acanthosis nigricans
D. Androgenic alopecia
4 Symptoms of polycystic ovary syndrome usually begin around ?
A. Menarche
B. First sexual contact
C. First child birth
D. Following oral contraceptive pill intake
4 In most women with PCOS, menarche occurs ?
A. Early
B. At the expected time
C. Late
D. Any of the above
5 Enhanced androgen production in PCOS is due to ?
A. Increased frequency of LH pulses
B. Synergistic action of insulin with LH
C. Reduced hepatic synthesis of sex hormone – binding globulin
(SHBG)
D. All of the above
6 Which of the following is false in PCOS ?
A. Increased pulse frequency of hypothalamic GnRH
B. Increased LH pulse frequency
C. Increased FSH pulse frequency
D. Hyperinsulinemia
7 In PCOS, LH to FSH ratio in plasma is characteristically greater
than ?
A. 0.75
B. 1.25
C. 1.75
D. 2.00
8 Chronic anovulation with estrogen present is found in all except
?
A. Brenner tumors
B. Isolated hypogonadotropic hypogonadism
C. Hypothyroidism
D. Krukenberg tumors
9 Chronic anovulation with estrogen present is found in all except
?
A. Kallmann syndrome
B. Adult-onset adrenal hyperplasia due to partial 21-hydroxylase
deficiency
C. Mucous cystadenomas
D. Cystic teratomas
10 If pregnancy is desired by a woman suffering from PCOS, which
of the following drugs is useful ?
A. Metformin
B. Thiazolidinediones
C. Clomiphene
D. All of the above
11 If pregnancy is desired by a woman suffering from PCOS,
ovulation can be induced with which of the following drugs ?
A. Human menopausal gonadotropin (hMG)
B. Purified FSH (Urofollitropin)
C. Gonadorelin
D. All of the above
12 If a woman having PCOS is not hirsute and does not desire
pregnancy, treatment of choice is ?
A. Medroxyprogesterone acetate
B. Combined estrogen-progestogen therapy
C. Cyproterone acetate
D. Drospirenone
13 If a woman having PCOS is hirsute and does not desire pregnancy,
treatment of choice is ?
A. Medroxyprogesterone acetate
B. Combined estrogen-progestogen therapy
C. Clomiphene
D. Human menopausal gonadotropin (hMG)
14 FSH secretion in PCOS can be enhanced by ?
A. Clomiphene
B. Human menopausal gonadotropin (hMG)
C. GnRH (gonadorelin)
D. All of the above
15 Which of the following drugs has antiandrogen effects ?
A. Cyproterone acetate
B. Estrogen
C. Drospirenone
D. All of the above
16 Chronic anovulation is associated with an increased risk of ?
A. Endometrial carcinoma
B. Cervical carcinoma
C. Vaginal carcinoma
D. All of the above
17 Teratogenic effect of which of the following drugs produces
“Neural-tube defects” ?
A. Warfarin
B. Thalidomide
C. Carbamazepine
D. Tetracycline
18 Teratogenic effect of which of the following drugs produces
“Neural-tube defects” ?
A. Warfarin
B. Thalidomide
C. Valproic acid
D. Tetracycline
19 Teratogenic effect of which of the following drugs produces
“Ebstein’s anomaly” ?
A. Angiotensin-converting–enzyme inhibitors
B. Lithium
C. Carbamazepine
D. Misoprostol
20 Teratogenic effect of which of the following drugs produces
“Moebius sequence” ?
A. Angiotensin-converting–enzyme inhibitors
B. Lithium
C. Carbamazepine
D. Misoprostol
21 Teratogenic effect of which of the following drugs produces
“Dandy–Walker syndrome” ?
A. Angiotensin-converting–enzyme inhibitors
B. Lithium
C. Carbamazepine
D. Warfarin
22 Teratogenic effect of which of the following drugs produces “aplasia
cutis” ?
A. Angiotensin-converting–enzyme inhibitors
B. Methimazole
C. Carbamazepine
D. Warfarin
23 Teratogenic effect of which of the following drugs produces
“necrotizing enterocolitis” ?
A. Nonsteroidal antiinflammatory drugs
B. Methimazole
C. Carbamazepine
D. Valproic acid
24 Teratogenic effect of which of the following drugs produces
“decreased skull ossification” ?
A. Nonsteroidal antiinflammatory drugs
B. Angiotensin-converting enzyme inhibitors
C. Carbamazepine
D. Valproic acid
25 Teratogenic effect of which of the following drugs produces
“Masculinization of female fetuses” ?
A. Nonsteroidal antiinflammatory drugs
B. Danazol
C. Diethylstilbestrol
D. Misoprostol
26 Teratogenic effect of which of the following drugs produces “renal
tubular dysgenesis” ?
A. Nonsteroidal antiinflammatory drugs
B. Angiotensin-converting–enzyme inhibitors
C. Diethylstilbestrol
D. Misoprostol
27 Retinoid embryopathy caused by teratogenic effect of “Isotretinoin”
includes all except ?
A. Optic-nerve blindness
B. Hypoplasia of nails
C. Thymic defects
D. Spontaneous abortion
28 Fetal hydantoin syndrome caused by teratogenic effect of
“Phenytoin” includes all except ?
A. Short nose with broad nasal bridge
B. Epicanthus
C. Webbed neck
D. Micrognathia
29 Fetal warfarin syndrome caused by teratogenic effect of “Warfarin”
includes all except ?
A. Agenesis of corpus callosum
B. Dandy–Walker malformations
C. Webbed neck
D. Hearing loss
30 Fetal Minamata disease is caused by the teratogenic effect of
which of the following drug ?
A. Warfarin
B. Methyl mercury
C. Hydantoin
D. Thalidomide