[MCQs] Transfusion Biology and Therapy- Part 1

I. Start the exam by click the “Start” button

See all quizzes of  the Transfusion Biology and Therapy   at here:

Transfusion Biology and Therapy- Part 1 |Transfusion Biology and Therapy- Part 2 |Transfusion Biology and Therapy- Part 3

1.Production of antibodies directed against blood group antigens of another individual are called ?
A. Alloantibodies
B. Heteroantibodies
C. Autoantibodies
D. Oligoantibodies

2.  Antibodies resulting from “natural” exposure are ?

A. IgG
B. IgM
C. IgA
D. IgE

3.  Antibodies that result from allogeneic exposure like transfusion or pregnancy are usually ?
A. IgG
B. IgM
C. IgA
D. IgE

4.  A and B antigens are ?
A. Carbohydrates
B. Proteins
C. Lipids
D. None of the above

5.  Immediate precursor upon which A & B antigen are added is ?
A. H substance
B. P substance
C. Z substance
D. K substance

6.  In the formation of H substance, the essential substance is ?
A. Fucose
B. Galactose
C. Fructose
D. Mannose

7.  Addition of N-acetylgalactosamine to H substance creates ?
A. A antigen
B. B antigen
C. Rh antigen
D. None of the above

8.  Addition of galactose to H substance creates ?
A. A antigen
B. B antigen
C. Rh antigen

D. None of the above

9.  Genes that determine A & B phenotypes are found on chromosome ?
A. 6 p
B. 7 p
C. 8 p
D. 9 p

10.  Genes that determine the A and B phenotypes are expressed in ?
A. Mendelian dominant manner
B. Mendelian recessive manner
C. Mendelian codominant manner
D. None of the above

11.  Which of the following “transferases” contributes to the formation of A or B blood groups ?
A. N-acetyl transferase (NAT)
B. Glutathione-S-transferase
C. Histone acetyl transferase (HAT)
D. Glycosyl transferases

12. Naturally occurring anti-A and anti-B antibodies are termed ?
A. Isoagglutinins
B. Homoagglutinins
C. Naturoagglutinins
D. AB agglutinins

13.  Isoagglutinin found in type AB individuals is ?
A. Anti-A
B. Anti-B
C. Anti-A + Anti-B
D. None of the above

14.  Isoagglutinin found in type O individuals is ?
A. Anti-A
B. Anti-B
C. Anti-A + Anti-B
D. None of the above

15. Individuals with Bombay phenotype produce antibodies to ?
A. H substance
B. A antigens
C. B antigens
D. All of the above

16.  Nonsecretors of A & B antigens by cells in the circulation are susceptible to ?
A. Hemolysis
B. Malignancy
C. Infections
D. All of the above

17.  Gene determining Rh phenotypes is found on chromosome ?
A. 1
B. 2
C. 3
D. 4

18.  Which of the following is Rh antigen ?
A. C
B. D
C. E
D. All of the above

19.  What percentage of of people lack the D antigen ?
A. About 15 %
B. About 20 %
C. About 25 %
D. About 30 %