[MCQs] Anemia and Polycythemia – Part 2

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Anemia and Polycythemia – Part 1 | Anemia and Polycythemia – Part 2

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1.Upon staining with supravital dye, reticulocytes are identified by what colour of punctate spots ?

1. Red
2. Blue
3. Green
4. Yellow

2. Reliable estimate of red cell production is provided by ?

1. EPO levels
2. Reticulocyte count
3. RDW
4. Polychromasia

3. “Shift” cells refer to ?

1. Older RBC’s
2. Prematurely released reticulocytes
3. Normoblasts
4. Any of the above

4. Erythroid cells take about how many days to mature ?

1. 2.5
2. 3.5
3. 4.5
4. 5.5

5. Absolute reticulocyte count is calculated by ?

1. Reticulocyte count x (Hemoglobin ÷ expected hemoglobin)
2. Reticulocyte count x  (Hemoglobin +  Hematocrit)
3. Reticulocyte count x  (Hemoglobin x  Hematocrit)
4. Reticulocyte count /  (Hemoglobin +  Hematocrit)

6. Which of the following about macrocytes is false ?

1. Red cells are larger than a small lymphocyte
2. Well hemoglobinized red cells
3. Often oval shaped
4. None of the above

7. Howell-Jolly bodies best relate to which of the following ?

1. Uremia
2. Nuclear remnants
3. Foreign bodies in the circulation
4. All of the above

8. Teardrop-shaped red cells best relates to ?

1. Uremia
2. Myelofibrosis
3. Thalassemia
4. Liver disease

9. Target red cells best relates to ?

1. Uremia
2. Myelofibrosis
3. Thalassemia
4. Acute hemolysis

10. Target cells are seen in ?

1. Liver disease
2. Thalassemia
3. Hemoglobin C disease
4. All of the above

11. Thermal injury may produce which of the following ?

1. Target cells
2. Burr cells
3. Howell-Jolly bodies
4. Red cell fragmentation

12. Burr cells are also called ?

1. Echinocytes
2. Acanthocytes
3. Elliptocytes
4.  Spherocytes

13. Echinocytes are found in patients with ?

1. Severe uremia
2. Glycolytic red cell enzyme defects
3. Microangiopathic hemolytic anemia
4. All of the above

14. Acanthocytes are present in which of the following conditions ?

1. Severe liver disease
2. Abetalipoproteinemia
3. Patients with McLeod blood group
4. All of the above

15. The normal serum iron range is ?

1. 10 to 50 µg / dL
2. 50 to 150 µg / dL
3. 150 to 250 µg / dL
4. 250 to 450 µg / dL

16. The normal serum TIBC range is ?

1. 100 to 150 µg / dL
2. 150 to 300 µg / dL
3. 300 to 360 µg / dL
4. 350 to 450 µg / dL

17. Percent transferrin saturation is calculated by ?

1. (TIBC x 100) ÷ Serum iron
2. (Serum iron + TIBC) ÷ 100
3. (Serum iron x 100) ÷ TIBC
4. (Serum iron ÷ TIBC) x 100

18. Adult males have average serum ferritin levels of about ?

1. 10 µg / L
2. 50 µg / L
3. 100 µg / L
4. 200 µg / L

19. Adult females have average serum ferritin levels of about ?

1. 10 µg / L
2. 30 µg / L
3. 60 µg / L
4. 90 µg / L

20. Ferritin is also an ?

1. Enzyme
2. Cytokine
3. Chemokine
4. Acute-phase reactant

21. Erythroblasts containing what are called sideroblasts ?

1. Hemosiderin
2. Ferritin
3. Residual RNA
4. All of the above

22. Hemolysis is most likely cause if reticulocyte production index is more than ?

1. 2.5
2. 3.5
3. 4.5
4. 5.5

23.Which of the following anemias is most frequent ?

1. Hypoproliferative
2. Maturation Disorders
3. Hemoglobinopathies
4. Hemolytic

24. A hypoproliferative anemia can result from ?

1. Marrow damage
2. Iron deficiency
3. Inadequate EPO stimulation
4. All of the above

25.Which of the following is the iron regulatory hormone ?

1. Erythropoietin
2. Transferrin
3. Hepcidin
4. All of the above

26. Nuclear maturation defects of RBC’s result from all except ?

1. Vitamin B12 deficiency
2. Folic acid deficiency
3. Iron deficiency
4. Methotrexate therapy

27. Cytoplasmic maturation defects of RBC’s result from ?

1. Severe iron deficiency
2. Abnormalities in heme synthesis
3. Abnormalities in globin synthesis
4. Any of the above

28. Increased red cell mass is present when hematocrit in  men  is ?

1. > 45 %
2. > 50 %
3. > 55 %
4. > 60 %

29. Gaisbock’s syndrome relates to ?

1. Spurious polycythemia
2. High altitude polycythemia
3. Ectopic EPO production
4. Familial polycythemia

30. EPO-producing neoplasms include ?

1. Hepatoma
2. Uterine leiomyoma
3. Cerebellar hemangiomas
4. All of the above