[MCQ] Pneumonia- Part 3

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Pneumonia- Part 3

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Question 1

Which of the following produces ciliostatic factor ?

A	Mycoplasma pneumoniae
B	Chlamydia pneumoniae
C	Influenza virus
D	Neisseria meningitidis

Question 1 Explanation:

Chlamydia pneumoniae produces a ciliostatic factor to counteract host defenses..

Question 2

Which of the following are resistant to microbicidal activity of phagocytes ?

A	Mycobacterium
B	Nocardia
C	Legionella spp
D	All of the above

Question 2 Explanation:

Mycobacterium, Nocardia & Legionella spp. are resistant to the microbicidal activity of phagocytes

Question 3

Virulence factor ‘pneumolysin’ interacts with any cell whose membrane contains ?

A	Peptides
B	Cholesterol
C	Triglyceride
D	Amino acids

Question 3 Explanation:

All pneumococci produce pneumolysin that interacts with any cell whose membrane contains cholesterol. Pneumococci also produce neuraminidase, hyaluronidase, and IgA1 protease.

Question 4

In patients with community-acquired pneumonia, which of the following is an independent risk factor for a fatal outcome ?

A	Lymphotoxin- AA genotype
B	TNF- 308:LT- +250 GC haplotype
C	TNF- 238 GA genotype
D	DRB11501/DQB10602 haplotype

Question 5

In patients with community-acquired pneumonia, which of the following is a risk factor for septic shock ?

A	Lymphotoxin- +250 AA genotype
B	TNF- 308:LT- +250 GC haplotype
C	TNF- 238 GA genotype
D	DRB11501/DQB10602 haplotype

Question 6

In patients with community-acquired pneumonia, which of the following is protective against septic shock ?

A	Lymphotoxin- AA genotype
B	TNF- 308:LT-a +250 GC haplotype
C	TNF- 238 GA genotype
D	DRB11501/DQB10602 haplotype

Question 6 Explanation:

In patients with CAP, the TNF- 238 GA genotype is an independent risk factor for a fatal outcome, lymphotoxin- (LT-) +250 AA genotype is a risk factor for septic shock, and the TNF- 308:LT- +250 GC haplotype is protective against septic shock.

Question 7

In the clinical entity designated ALPS, ‘S’ stands for ?

A	Smoking
B	Sepsis
C	Sedantry
D	Supine

Question 7 Explanation:

Clinical entity designated ALPS (alcoholism, leukopenia, pneumococcal sepsis) is associated with a mortality rate of 80%

Question 8

‘PORT risk score’ is used to classify ?

A	Community-acquired pneumonia
B	Bronchiectasis
C	Interstitial lung disease
D	Interstitial lung disease

Question 8 Explanation:

PORT stands for Pneumonia Patient Outcomes Research Team. PORT risk class stratifies mortality rate in Community-Acquired Pneumonia.

Question 9

The single most useful clinical sign of severity of pneumonia in a person without underlying lung disease is ?

A	Respiratory rate >30/minute
B	Pulse rate > 100/minute
C	Hypothermia
D	Postural fall of SBP > 10 mm Hg

Question 9 Explanation:

The single most useful clinical sign of the severity of pneumonia is a respiratory rate of >30/minute in a person without underlying lung disease.

Question 10

Which of the following bacterial pneumonia has the highest mortality rate ?

A	P. aeruginosa
B	Klebsiella spp.
C	E. coli
D	S. aureus

Question 10 Explanation:

Mortality rate is highest (>50%) for pneumonia due to P. aeruginosa, followed by Klebsiella spp., E. coli, S. aureus, and Acinetobacter spp. (30 to 35%).

Question 11

Which capsular serotype pneumococcus is associated with a higher mortality rate ?

A	1
B	2
C	3
D	4

Question 11 Explanation:

Capsular serotype 3 pneumococcus is associated with a much higher mortality rate than serotype 1.

Question 12

In a case of pneumonia, pneumatoceles in chest radiograph suggests infection with ?

A	Mycobacterium tuberculosis
B	S. aureus
C	Escherichia coli
D	Legionella

Question 13

Microorganisms isolated from sputum that should always be considered pathogens include ?

A	Mycobacterium tuberculosis
B	Legionella spp.
C	Blastomyces dermatitidis
D	All of the above

Question 14

Microorganisms isolated from sputum that should always be considered pathogens include ?

A	Blastomyces dermatitidis
B	Histoplasma capsulatum
C	Histoplasma capsulatum
D	All of the above

Question 15

Aerobic pathogen most often implicated in causation of aspiration-associated lung abscesses is ?

A	Streptococcus milleri
B	Bacteroides fragilis
C	Prevotella oralis
D	Fusobacterium nucleatum

Question 15 Explanation:

Most aspiration-associated lung abscesses are due to a combination of aerobic and anaerobic bacteria, with an average of six or seven bacterial species identified in an individual case. Streptococcus milleri is one of the principal aerobic pathogens.

Question 16

Gastric acid aspiration leading to aspiration pneumonitis requires following characteristics of gastric aspirate ?

A	pH < 2.5 & gastric aspirate volume of > 0.3 mL/kg
B	pH < 5 & gastric aspirate volume of > 0.3 mL/kg
C	pH < 2.5 & gastric aspirate volume of > 0.6 mL/kg
D	pH < 5 & gastric aspirate volume of > 0.6 mL/kg

Question 16 Explanation:

Gastric aspirate pH of <2.5 & volume >0.3 mL/kg (20 to 25 mL in adults) is required for the development of aspiration pneumonitis.

Question 17

Which of the following is a respiratory fluoroquinolone ?

A	Moxifloxacin
B	Gemifloxacin
C	Levofloxacin
D	All of the above

Question 17 Explanation:

Respiratory fluoroquinolones include moxifloxacin, gemifloxacin and levofloxacin.

Question 18

Hospital-acquired pneumonia (HAP) is defined as pneumonia occurring how many hours after hospital admission ?

A	At least 12 hours
B	At least 24 hours
C	At least 36 hours
D	At least 48 hours

Question 18 Explanation:

HAP is defined as pneumonia occurring at least 48 hours after hospital admission and not incubating at the time of admission.

Question 19

Cefoxitin, Cefotetan, and Cefmetazole belong to which generation of cephalosporins ?

A	First
B	Second
C	Third
D	None of the above

Question 19 Explanation:

Cephamycins (cefoxitin, cefotetan, & cefmetazole) are structurally different from true cephalosporins & display enhanced stability in the presence of ESBLs. Some consider cephamycins to be subset of second-generation cephalosporins

Question 20

ESBL-producing isolates should be considered resistant to ?

A	All penicillins
B	Cephalosporins
C	Aztreonam
D	All of the above

Question 20 Explanation:

ESBL-producing isolates should be considered resistant to all penicillins, cephalosporins & aztreonam

Question 21

Which of the following organisms have been designated as “core pathogens” in the American Thoracic Society’s guidelines for treatment of nosocomial pneumonia ?

A	S. pneumoniae
B	H. influenzae
C	S. aureus
D	All of the above

Question 22

According to American Thoracic Society (ATS) guidelines for treatment of nosocomial pneumonia “core pathogens” include all except ?

A	Staphylococcus aureus
B	Pneumococcus
C	Pseudomonas aeruginosa
D	E. coli

Question 22 Explanation:

“Core pathogens” in American Thoracic Society’s guidelines for the treatment of nosocomial pneumonia are S. pneumoniae, H. influenzae, S. aureus, and enteric gram-negative bacilli (E. coli, Klebsiella spp., Proteus spp., and Serratia marcescens)

Question 23

British Thoracic Society (BTS) criteria for severe community acquired pneumonia includes all parameters except ?

A	Pulse rate
B	Blood pressure
C	Respiratory rate
D	Blood urea level

Question 23 Explanation:

British Thoracic Society Rule for definition of severe community-acquired pneumonia includes confusion, urea, respiratory rate and blood pressure.

Question 24

In a case of pneumonia, urine examination can help in the etiological diagnosis in ?

A	Mycoplasma
B	Chlamydia
C	Coxiella
D	L. pneumophila serogroup 1

Question 25

In a case of pneumonia, urine examination can help in the etiological diagnosis in ?

A	Mycoplasma
B	Chlamydia
C	Coxiella
D	S. pneumoniae

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See all quizzes of Pneumonia at here:

Pneumonia- Part 1| Pneumonia- Part 2| Pneumonia- Part 3

1. Which of the following produces ciliostatic factor ?
A. Mycoplasma pneumoniae
B. Chlamydia pneumoniae
C. Influenza virus
D. Neisseria meningitidis

2. Which of the following are resistant to microbicidal activity of phagocytes ?
A. Mycobacterium

B. Nocardia
C. Legionella spp.
D. All of the above

3. Virulence factor ‘pneumolysin’ interacts with any cell whose membrane contains ?
A. Peptides
B. Cholesterol
C. Triglyceride
D. Amino acids

4. In patients with community-acquired pneumonia, which of the following is an independent risk factor for a fatal outcome ?
A. Lymphotoxin- AA genotype
B. TNF- 308:LT- +250 GC haplotype
C. TNF- 238 GA genotype
D. DRB1*1501/DQB1*0602 haplotype
5. In patients with community-acquired pneumonia, which of the following is a risk factor for septic shock ?
A. Lymphotoxin- +250 AA genotype
B. TNF- 308:LT- +250 GC haplotype
C. TNF- 238 GA genotype
D. DRB1*1501/DQB1*0602 haplotype
6. In patients with community-acquired pneumonia, which of the following is protective against septic shock ?
A. Lymphotoxin- AA genotype
B. TNF- 308:LT-a +250 GC haplotype
C. TNF- 238 GA genotype
D. DRB1*1501/DQB1*0602 haplotype

7. In the clinical entity designated ALPS, ‘S’ stands for ?
A. Smoking
B. Sepsis
C. Sedantry
D. Supine

8. ‘PORT risk score’ is used to classify ?
A. Community-acquired pneumonia
B. Bronchiectasis
C. Interstitial lung disease

D. Pulmonary thromboembolism

9. The single most useful clinical sign of severity of pneumonia in a person without underlying lung disease is ?
A. Respiratory rate >30/minute
B. Pulse rate > 100/minute
C. Hypothermia
D. Postural fall of SBP > 10 mm Hg

10. Which of the following bacterial pneumonia has the highest mortality rate ?
A. P. aeruginosa
B. Klebsiella spp.
C. E. coli
D. S. aureus

11. Which capsular serotype pneumococcus is associated with a higher mortality rate ?
A. 1
B. 2
C. 3
D. 4

12. In a case of pneumonia, pneumatoceles in chest radiograph suggests infection with ?
A. Mycobacterium tuberculosis
B. S. aureus
C. Escherichia coli
D. Legionella
13. Microorganisms isolated from sputum that should always be considered pathogens include ?
A. Mycobacterium tuberculosis
B. Legionella spp.
C. Blastomyces dermatitidis
D. All of the above
14. Microorganisms isolated from sputum that should always be considered pathogens include ?
A. Blastomyces dermatitidis
B. Histoplasma capsulatum
C. Coccidioides immitis
D. All of the above

15. Aerobic pathogen most often implicated in causation of aspiration-associated lung abscesses is ?
A. Streptococcus milleri
B. Bacteroides fragilis
C. Prevotella oralis
D. Fusobacterium nucleatum

16. Gastric acid aspiration leading to aspiration pneumonitis requires following characteristics of gastric aspirate ?
A. pH < 2.5 & gastric aspirate volume of > 0.3 mL/kg
B. pH < 5 & gastric aspirate volume of > 0.3 mL/kg
C. pH < 2.5 & gastric aspirate volume of > 0.6 mL/kg
D. pH < 5 & gastric aspirate volume of > 0.6 mL/kg

17. Which of the following is a respiratory fluoroquinolone ?
A. Moxifloxacin
B. Gemifloxacin
C. Levofloxacin
D. All of the above

18. Hospital-acquired pneumonia (HAP) is defined as pneumonia occurring how many hours after hospital admission ?
A. At least 12 hours
B. At least 24 hours
C. At least 36 hours
D. At least 48 hours

19. Cefoxitin, Cefotetan, and Cefmetazole belong to which generation of cephalosporins ?
A. First
B. Second
C. Third
D. None of the above

20. ESBL-producing isolates should be considered resistant to ?
A. All penicillins
B. Cephalosporins

C. Aztreonam
D. All of the above

21. Which of the following organisms have been designated as “core pathogens” in the American Thoracic Society’s guidelines for treatment of nosocomial pneumonia ?
A. S. pneumoniae
B. H. influenzae
C. S. aureus
D. All of the above
22. According to American Thoracic Society (ATS) guidelines for treatment of nosocomial pneumonia “core pathogens” include all except ?
A. Staphylococcus aureus
B. Pneumococcus
C. Pseudomonas aeruginosa
D. E. coli

23. British Thoracic Society (BTS) criteria for severe community acquired pneumonia includes all parameters except ?
A. Pulse rate
B. Blood pressure
C. Respiratory rate
D. Blood urea level

24. In a case of pneumonia, urine examination can help in the etiological diagnosis in ?
A. Mycoplasma
B. Chlamydia
C. Coxiella
D. L. pneumophila serogroup 1
25. In a case of pneumonia, urine examination can help in the etiological diagnosis in ?
A. Mycoplasma
B. Chlamydia
C. Coxiella
D. S. pneumoniae

Pneumonia

[MCQ] Pneumonia- Part 3

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Pneumonia- Part 3

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