[MCQ] Hypersensitivity Pneumonitis & Pulmonary Infiltrates with Eosinophilia- Part 2

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1.In hypereosinophilic syndrome, the cardiac abnormality is ?
A. Tricuspid valve abnormalities
B. Endomyocardial fibrosis
C. Restrictive, biventricular cardiomyopathy
D. All of the above
2.  Besides lung, which other organ is involved in allergic angiitis and granulomatosis of Churg and Strauss ?
A. Skin
B. Kidney
C. Nervous system
D. All of the above
3.  In asthma, use of which of the following drugs is associated with Churg-Strauss syndrome ?
A. Beta agonists
B. Chromolyns

C. Leukotriene-modifying agents
D. Anticholinergics
4.  Most common route of entry of aspergillus spores is ?
A. Inhalation
B. Ingestion
C. Urinary tract
D. Skin

5.  Invasive aspergillosis of lung tissue is found in ?
A. Granulocyte count in peripheral blood of <500/uL
B. Treatment with supraphysiologic doses of glucocorticoids
C. History of treatment with cytotoxic drugs
D. All of the above
6.  Aspergillus infection in a neutropenic patient is characterized by ?
A. Hyphal invasion of blood vessels
B. Thrombosis, necrosis
C. Hemorrhagic infarction
D. All of the above
7.  Term allergic bronchopulmonary aspergillosis (ABPA) denotes the condition of patients with preexisting asthma who have ?
A. Eosinophilia
B. IgE antibody to Aspergillus
C. Fleeting pulmonary infiltrates from bronchial plugging
D. All of the above

8.  Endobronchial saprophytic pulmonary aspergillosis presents in a patient with prior ?
A. Pulmonary tuberculosis
B. Sarcoidosis
C. Histoplasmosis
D. All of the above
9.  In allergic bronchopulmonary aspergillosis (ABPA), fleeting eosinophilic infiltrates involve which lobes of lung ?
A. Upper lobes
B. Middle lobes
C. Lower lobes
D. Any of the above

10. The earliest CT finding in invasive aspergillosis is ?
A. Pulmonary nodules

B. Pulmonary infiltrate
C. Pleural effusion
D. Pneumothorax
11.  Halo sign & crescent sign are radiological findings in ?
A. Invasive aspergillosis of the lung
B. Bronchiectasis
C. Bronchogenic carcinoma
D. Atelectasis

12. Detection of galactomannan antigen in serum suggests the diagnosis of ?
A. Invasive aspergillosis of the lung
B. Bronchiectasis
C. Bronchogenic carcinoma
D. Atelectasis

13.  Which of the following can give false positive results for galactomannan antigen ?
A. Concomitant use of piperacillin–tazobactam antibiotic
B. Concomitant use of beta-lactam antibiotic
C. Gluconate containing IV fluids
D. All of the above

14.  Drug of choice as primary therapy for invasive aspergillosis is ?
A. Posaconazole
B. Itraconazole
C. Voriconazole
D. Amphotericin B

15.  Which of the following is an “Echinocandin” ?
A. Caspofungin
B. Micafungin
C. Anidulafungin
D. All of the above

14.  Drugs for treatment of aspergillosis include ?
A. IV amphotericin B

B. Liposomal amphotericin B
C. Itraconazole
D. All of the above
15.  Drugs for treatment of aspergillosis include ?
A. Intravenous voriconazole
B. Intravenous caspofungin
C. Itraconazole
D. All of the above
16.  Which of the following is not effective in treatment of aspergillosis ?
A. Fluconazole
B. Voriconazole
C. Caspofungin
D. Itraconazole