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Genetics- Part 2
See all quizzes of Genetics- Part 2 here:
1 Urinary bladder and urethra are formed from ?
A. Endoderm
B. Mesoderm
C. Ectoderm
D. All of the above
2 Allogeneic transplantation refers to transplantation of ?
A. Genetically identical marrow
B. Own stored marrow
C. Genetically non-identical marrow
D. None of the above
3 Syngeneic transplantation refers transplantation of ?
A. Genetically identical marrow
B. Own stored marrow
C. Genetically non-identical marrow
D. None of the above
4 Diseases commonly treated with autologous hematopoietic stemcell
transplantation include all except ?
A. Neuroblastoma
B. Ovarian cancer
C. Germ-cell tumors
D. Aplastic anemia
5 Which of the following is a mitochondrial disease ?
A. MELAS syndrome
B. Leber’s optic atrophy
C. Kearns-Sayre syndrome (KSS)
D. All of the above
6 When are Screening tests for Neural Tube defects (NTD) done
during pregnancy ?
A. First trimester
B. Second Trimester
C. Third Trimester
D. All of the above
7 During pregnancy, alpha fetoprotein (AFP) is synthesized by ?
A. Fetal Liver
B. Fetal Lung
C. Umbilical Cord
D. Placental tissue
8 Which of the following are “Second trimester serum markers”
used for prenatal screening of Down syndrome ?
A. AFP, hCG, uE3 & Inhibin-A
B. AFP, hCG & Inhibin-A
C. hCG, uE3 & Inhibin-A
D. hCG
9 In maternal serum, pregnancy suspected of Down syndrome will
show ?
A. Low AFP, high hCG, low unconjugated estriol & high inhibin-A
B. High AFP, high hCG, low unconjugated estriol & high inhibin-A
C. High AFP, high hCG, low unconjugated estriol & low inhibin-A
D. High AFP, high hCG, low unconjugated estriol & high inhibin-A
10 Mutation on IT15 gene causing Huntington’s disease (HD) is located
on which chromosome ?
A. 4
B. 7
C. X
D. 21
11 Huntington’s disease is associated with which triplet repeat ?
A. GGG
B. CAG
C. GAA
D. CGA
12 In an autosomal recessive disorder, what is the chance of having
an affected child if two unaffected people who carry one copy of
mutated gene (carriers) each ?
A. 100 %
B. 50 %
C. 25 %
D. 0 %
13 If a women is suffering from any X-linked recessive disorder,
then what is the chance of her passing the mutant gene to her son
(XY) and daughter (XX) respectively?
A. 50 : 50
B. 50 : 30
C. 100 : 100
D. 100 : 50
14 What is the technical name given to the affected individual through
whom a family with a genetic disorder is analysed ?
A. Mosaic
B. Proband
C. Genetic lead
D. Karyotype
15 Which type of cell division ensures that humans have the same
number of chromosomes (46) in each generation?
A. Mitosis
B. Meiosis
C. Binary fission
D. Budding
16 How many chromosomes does each sperm and ova contribute at
in the formation of zygote ?
A. 23 chromosomes
B. 46 chromosomes
C. 23 pairs of chromosome
D. 46 pairs of chromosome
17 The exchange of chromosomal segments between nonhomologous
chromosomes is known as ?
A. Translocation
B. Inversion
C. Heterozygosity
D. Duplication
18 Chromosome number in somatic cells of Drosophila is ?
A. 2
B. 4
C. 6
D. 8
19 DNA segment that participates in ‘crossing over’ is called ?
A. Replicon
B. Recon
C. Cistron
D. Muton
20 Inheritance of skin colour is an example of ?
A. Polygenic inheritance
B. Mendelian inheritance
C. Monogenic inheritance
D. Autosomal inheritance
21 Which condition is caused by a mutation that involves an entire
chromosome rather than a single gene ?
A. Thalessemia
B. Hemophilia
C. Phenylketonuria
D. Down syndrome
22 Down syndrome in humans is due to ?
A. Monosomy
B. Nullisomy
C. Triploidy
D. Trisomy
23 The parents of a colour blind daughter would be ?
A. Colour blind father & carrier mother
B. Carrier father & colour blind mother
C. Both parents are colour blind
D. None of the parents are colour blind
24 Which of the following is true when a colour blind man marries
the daughter of a colour blind person ?
A. 50 % of sons will be colour blind
B. 50 % of daughters will be colour blind
C. All sons will be colour blind
D. Some sons and some daughters will be colour blind
25 In humans, a recessive gene can express either in homozygous
condition, or singly when it is present on ?
A. Autosomes
B. X chromosome of female
C. X chromosome of male
D. None of the above
