[MCQ] Disorders of the Autonomic Nervous System- Part 2

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1 Which of the following is a test for sweating ?
A. Quantitative sudomotor axon reflex test (QSART)
B. Thermoregulatory sweat test (TST)
C. Measurement of galvanic skin responses
D. All of the above
2 A reduced or absent response in ‘Quantitative sudomotor axon
reflex test (QSART)’ indicates ?
A. Lesion of preganglionic sudomotor axon
B. Lesion of postganglionic sudomotor axon
C. Lesion of pre & postganglionic sudomotor axon
D. None of the above

3 If both QSART and TST are absent, the lesion is in ?
A. Preganglionic sudomotor axon
B. Postganglionic sudomotor axon
C. Pre & postganglionic sudomotor axon
D. None of the above

4 If QSART is intact but TST shows anhidrosis, lesion is in ?
A. Preganglionic sudomotor axon
B. Postganglionic sudomotor axon
C. Pre & postganglionic sudomotor axon
D. None of the above

5 Multiple system atrophy (MSA) comprises autonomic failure and
which of the following ?
A. Horner’s syndrome
B. Wernicke-Korsakoff syndrome
C. Shy-Drager syndrome
D. Shapiro’s syndrome

6 Parkinsonism seen in multiple system atrophy features which of
the following ?
A. No rest tremor
B. Not responsive to levodopa
C. Levodopa-induced dyskinesia uncommon
D. All of the above
7 Autonomic dysfunction is a common feature in ?
A. Dementia with Lewy bodies (DLB)
B. Multiple system atrophy (MSA)
C. Parkinson’s disease
D. All of the above

8 Autonomic dysreflexia is common in patients with traumatic spinal
cord lesion above which level ?
A. C6
B. T3
C. T12
D. L2

9 Neuromuscular junction disorders accompanied by autonomic
involvement include ?
A. Porphyria
B. Botulism
C. Chronic alcoholism
D. Guillain-Barré syndrome

10 Autonomic neuropathy typically begins how many years after the
onset of diabetes mellitus ?
A. ~ 5
B. ~ 7
C. ~ 10
D. ~ 14

12 Autoantibodies against which of the following is present in
autoimmune autonomic neuropathy (AAN) ?
A. A3 AChR
B. B3 AChR
C. C3 AChR
D. D3 AChR

13 Botulinum toxin blocks release of which of the following ?
A. Norepinephrine
B. Acetylcholine
C. Serotonin
D. All of the above

14 Which of the following statements about Pure Autonomic Failure
(PAF) is false ?
A. Involvement of postganglionic sympathetic neurons
B. Low supine plasma NE levels
C. Noradrenergic supersensitivity
D. None of the above

15 Which of the following is false about Postural Orthostatic
Tachycardia Syndrome (POTS) ?
A. Symptomatic orthostatic hypotension
B. Increase in heart rate of > 30 beats/min with standing
C. Women affected five times more often than men
D. Occurs between 15 and 50 years of age

16 Hereditary sensory and autonomic neuropathy I (HSAN I) is best
related to which of the following ?
A. Dermatan sulfate
B. Sphingomyelin
C. Glucosyl ceramide
D. Heparan sulfate

17 The defective gene in HSAN III is ?
A. IKBKAP
B. SPTLC2
C. SPTLC3
D. SPTLC4

18 Cause of autonomic storm is ?
A. Brain and spinal cord injury
B. Autonomic neuropathy
C. Pheochromocytoma
D. All of the above

19 Drug that can produce autonomic storm is ?
A. Phenylpropanolamine
B. Cocaine
C. Amphetamine
D. All of the above

20 Neuroleptic malignant syndrome is seen in psychotic patients
treated with ?
A. Amphetamine
B. Phenylpropanolamine
C. Phenothiazine
D. Any of the above

21 Allodynia refers to ?
A. Perception of nonpainful stimulus as painful
B. Exaggerated pain response to a painful stimulus
C. Spontaneous pain
D. All of the above

22 Which of the following must be present for the diagnosis of
complex regional pain syndrome (CRPS) ?
A. Vasomotor dysfunction
B. Sudomotor abnormalities
C. Focal edema
D. Any of the above

23 CRPS type II develops after ?
A. Injury to a specific peripheral nerve
B. Myocardial infarction
C. Stroke
D. Limb injury