Home Laboratory QuizzesImmunology Quizzes [Immunology] The Immunodeficiency Diseases Quizzes (8 tests)

[Immunology] The Immunodeficiency Diseases Quizzes (8 tests)

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Immunodeficiency Diseases

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For which immunodeficiency syndrome should patients receive irradiated blood products to protect against the development of GvH disease?

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T-cell subset enumeration by flow cytometry would be most useful in making the diagnosis of which disorder?

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What clinical manifestations would be seen in a patient with myeloperoxidase deficiency?

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Defects in which arm of the immune system are most commonly associated with severe illness after administration of live virus vaccines?

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Which of the following statements applies to Bruton’s X-linked agammaglobulinemia?

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DiGeorge anomaly may be characterized by all of the following except

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A 3-year-old boy is hospitalized because of recurrent bouts of pneumonia. Laboratory tests are run, and the following findings are noted: prolonged bleeding time, decreased platelet count, increased level of serum alphafetoprotein, and a deficiency of naturally occurring isohemagglutinins. Based on these results, which is the most likely diagnosis?

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Which of the following is associated with AT?

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[Immunology] The Immunodeficiency Diseases Quizzes (8 tests)
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1. For which immunodeficiency syndrome should patients receive irradiated blood products to protect against the development of GvH disease?
a. Bruton’s agammaglobulinemia
b. Severe IgA deficiency
c. SCID
d. CGD
2. T-cell subset enumeration by flow cytometry would be most useful in making the diagnosis of which disorder?
a. Bruton’s agammaglobulinemia
b. Severe IgA deficiency
c. SCID
d. Multiple myeloma
3. What clinical manifestations would be seen in a patient with myeloperoxidase deficiency?
a. Defective T-cell function
b. Inability to produce IgG
c. Defective NK cell function
d. Defective neutrophil function
4. Defects in which arm of the immune system are most commonly associated with severe illness after administration of live virus vaccines?
a. Cell-mediated immunity
b. Humoral immunity
c. Complement
d. Phagocytic cells
5. Which of the following statements applies to Bruton’s X-linked agammaglobulinemia?
a. It typically appears in females.
b. There is a lack of circulating CD19 positive B cells.
c. T cells are abnormal.
d. There is a lack of pre-B cells in the bone marrow
6. DiGeorge anomaly may be characterized by all of the following except
a. autosomal recessive inheritance.
b. cardiac abnormalities.
c. parathyroid hypoplasia.
d. decreased number of mature T cells.
7. A 3-year-old boy is hospitalized because of recurrent bouts of pneumonia. Laboratory tests are run, and the following findings are noted: prolonged bleeding time, decreased platelet count, increased level of serum alphafetoprotein, and a deficiency of naturally occurring isohemagglutinins. Based on these results, which is the most likely diagnosis?
a. PNP deficiency
b. Selective IgA deficiency
c. SCID
d. WAS
8. Which of the following is associated with AT?
a. Inherited as an autosomal recessive
b. Defect in both cellular and humoral immunity
c. Chromosomal breaks in lymphocytes
d. All of the above

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