Home Laboratory QuizzesImmunology Quizzes [Immunology] The Transplantation Immunology Quizzes (8 tests)

[Immunology] The Transplantation Immunology Quizzes (8 tests)

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Transplantation Immunology

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The type of allograft rejection associated with vascular and parenchymal injury with lymphocyte infiltrates is which of the following?

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Antigen receptors on T lymphocytes bind HLA class II molecules with the help of which accessory molecule?

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Patients at risk for graft-versus-host disease (GVHD) include each of the following, except recipients of

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HLA molecules exhibit all of the following properties, except that they

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Kidney allograft loss from intravascular thrombosis without cellular infiltration 5 days post-transplant raises the suspicion level about which primary rejection mechanism?

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Which reagents would be used in a direct (forward) donor–recipient crossmatch test?

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The indirect allorecognition pathway involves which one of the following mechanisms?

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Which immunosuppressive agent selectively inhibits IL-2 receptor-mediated activation of T cells and causes clearance of activated T cells from the circulation?

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[Immunology] The Transplantation Immunology Quizzes (8 tests)
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1. The type of allograft rejection associated with vascular and parenchymal injury with lymphocyte infiltrates is which of the following?
a. Hyperacute rejection
b. Acute cellular rejection
c. Acute humoral rejection
d. Chronic rejection
2. Antigen receptors on T lymphocytes bind HLA class II molecules with the help of which accessory molecule?
a. CD2
b. CD3
c. CD4
d. CD8
3. Patients at risk for graft-versus-host disease (GVHD) include each of the following, except recipients of
a. bone marrow transplants.
b. lung transplants.
c. liver transplants.
d. irradiated leukocytes.
4. HLA molecules exhibit all of the following properties, except that they
a. belong to the immunoglobulin superfamily.
b. are heterodimeric.
c. are integral cell membrane glycoproteins.
d. are monomorphic.
5. Kidney allograft loss from intravascular thrombosis without cellular infiltration 5 days post- transplant raises the suspicion level about which primary rejection mechanism?
a. Hyperacute rejection
b. Accelerated humoral rejection
c. Acute humoral rejection
d. Acute cellular rejection
6. Which reagents would be used in a direct (forward) donor–recipient crossmatch test?
a. Donor serum and recipient lymphocytes rabbit serum complement
b. Recipient serum and donor lymphocytes rabbit serum complement
c. Donor stimulator cells recipient responder cells complete culture medium
d. Recipient stimulator cells donor responder cells complete culture medium
7. The indirect allorecognition pathway involves which one of the following mechanisms?
a. Processed peptides from polymorphic donor proteins restricted by recipient HLA class II molecules
b. Processed peptides from polymorphic recipient proteins restricted by donor HLA class I molecules
c. Intact polymorphic donor protein molecules recognized by recipient HLA class I molecules
d. Intact polymorphic donor protein molecules recognized by recipient HLA class II molecules
8. Which immunosuppressive agent selectively inhibits IL-2 receptor-mediated activation of T cells and causes clearance of activated T cells from the circulation?
a. Mycophenolate mofetil
b. Cyclosporine mofetil
c. Corticosteroids
d. Daclizumab

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