Select the one best response to each question!
The ability of a single cytokine to alter the expression of several genes is called
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Which of the following can be attributed to IL-1?
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Which of the following are target cells for IL-3?
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Wrong!
A lack of IL-4 might result in which of the following?
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Wrong!
Which of the following is also known as the T-cell growth factor?
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Wrong!
Which chemokine receptor does HIV need for cellspecific binding?
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Wrong!
IFN- and IFN- differ in which way from IFN-?
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Wrong!
A patient in septic shock caused by a gram-negative bacterial infection exhibits the following symptoms: high fever, very low blood pressure, and disseminated intravascular coagulation. Which cytokine is the most likely contributor to these symptoms?
Correct!
Wrong!
IL-10 acts as an antagonist to what cytokine?
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Wrong!
Which would be the best assay to measure a specific cytokine?
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Wrong!
Cytokines Quizzes (10 tests)
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| 1. The ability of a single cytokine to alter the expression of several genes is called a. redundancy. b. pleiotropy. c. autocrine stimulation. d. endocrine effect. |
| 2. Which of the following can be attributed to IL-1? a. Mediator of the innate immune response b. Differentiation of stem cells c. Halts growth of virally infected cells d. Stimulation of mast cells |
| 3. Which of the following are target cells for IL-3? a. Myeloid precursors b. Lymphoid precursors c. Erythroid precursors d. All of the above |
| 4. A lack of IL-4 might result in which of the following? a. Inability to fight off viral infections b. Increased risk of tumors c. Lack of IgE d. Decreased eosinophil count |
| 5. Which of the following is also known as the T-cell growth factor? a. IFN-ɣ b. IL-12 c. IL-2 d. IL-10 |
| 6. Which chemokine receptor does HIV need for cellspecific binding? a. CCR1 b. CCR3 c. CCR4 d. CCR5 |
| 7. IFN- and IFN- differ in which way from IFN-? a. IFN- and IFN- are called immune interferons, and IFN- is not. b. IFN- and IFN- primarily activate macrophages, while IFN- halts viral activity. c. They are made primarily by activated T cells, while IFN- is made by fibroblasts. d. IFN- and IFN- inhibit cell proliferation, while IFN- stimulates antigen presentation by class II MHC molecules. |
| 8. A patient in septic shock caused by a gram-negative bacterial infection exhibits the following symptoms: high fever, very low blood pressure, and disseminated intravascular coagulation. Which cytokine is the most likely contributor to these symptoms? a. IL-2 b. TNF c. IL-12 d. IL-7 |
| 9. IL-10 acts as an antagonist to what cytokine? a. IL-4 b. TNF-α c. IFN-ɣ d. TGF-β |
| 10. Which would be the best assay to measure a specific cytokine? a. Blast formation b. T-cell proliferation c. Measurement of leukocyte chemotaxis d. ELISA testing |
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