Select the ONE answer that is BEST in each case.
Megaloblastic anemias can be caused by
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Megaloblastic anemia related to folic acid deficiency is associated with
Correct!
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The underlying type A gastritis that causes pernicious anemia is immunologically related to
Correct!
Wrong!
Cobalamin transport is mediated by
Correct!
Wrong!
In megaloblastic anemia, the typical erythrocytic indices are
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The peripheral erythrocyte morphology in folate deficiency is similar to pernicious anemia, and the RBCs are
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Wrong!
In a case of classic pernicious anemia, the patient has
Correct!
Wrong!
Megaloblastic Anemias
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| 1. Megaloblastic anemias can be caused by A. tapeworm infestation B. gastric resection C. nutritional deficiency D. all of the above |
| 2. Megaloblastic anemia related to folic acid deficiency is associated with A. abnormal absorption B. increased utilization C. nutritional deficiency D. all of the above |
| 3. The underlying type A gastritis that causes pernicious anemia is immunologically related to A. autoantibody to IF B. low serum gastrin C. autoantibody to parietal cells D. both A and C |
| 4. Cobalamin transport is mediated by A. IF B. TC II C. R proteins D. all of the above |
| 5. In megaloblastic anemia, the typical erythrocytic indices are A. MCV increased, MCH increased, and MCHC normal B. MCV increased, MCH variable, and MCHC normal C. MCV increased, MCH decreased, and MCHC normal D. MCV normal, MCH increased, and MCHC normal |
| 6. The peripheral erythrocyte morphology in folate deficiency is similar to pernicious anemia, and the RBCs are A. small B. normal size C. large |
| 7. In a case of classic pernicious anemia, the patient has A. leukopenia B. hypersegmented neutrophils C. anemia D. all of the above |
| 8. The reticulocyte count in a patient with untreated pernicious anemia is characteristically A. 0% B. 0.3% C. <1.0% D. approximately 1.8% |
