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Select the ONE answer that is BEST in each case.
The etiology of IDA is
| 1. The etiology of IDA is A. nutritional deficiency B. faulty iron absorption C. excessive loss of iron D. all of the above |
| 2. Iron defi ciency is still common in A. toddlers B. adolescent girls C. women of childbearing age D. all of the above |
| 3. _____ Decreased iron intake
A. Sprue |
| 4. _____ Faulty iron absorption
A. Sprue |
| 5. _____ Pathological iron loss
A. Sprue |
| 6. _____ Physiological iron loss
A. Sprue |
| 7. _____ Increased iron utilization A. Sprue B. Colon cancer C. Adolescent growth spurt D. Menstruation E. Meat-poor diet |
| 8. The average adult has _____ g of total iron. A. 0.2 to 1.4 B. 1.5 to 3.4 C. 3.5 to 5.0 D. 5.1 to 10.0 |
| 9. Most functional iron in humans is found in A. the bone marrow B. the liver C. hemoglobin molecules of erythrocytes (RBCs) D. the free hemoglobin in the circulation |
| 12. Most ingested iron is readily absorbed into the body in the A. stomach and duodenum B. duodenum and upper jejunum C. ileum and duodenum D. upper jejunum and ileum |
| 13. Transferrin represents a A. storage form of iron B. beta globulin that moves iron C. glycoprotein that moves iron D. both B and C |
| 14. In IDA, the erythrocytic indices are typically A. MCV increased, MCH decreased, and MCHC decreased B. MCV decreased, MCH decreased, and MCHC decreased C. MCV decreased, MCH increased, and MCHC decreased D. MCV decreased, MCH decreased, and MCHC normal |
| 15. The peripheral blood smear demonstrates _____ red blood cells in IDA. A. microcytic, hypochromic B. macrocytic, hypochromic C. macrocytic and spherocytic D. either A or B |
| 16. In IDA, the A. serum iron is severely decreased and the TIBC is increased B. serum iron is decreased and the TIBC is normal C. serum iron is normal and the TIBC is normal D. serum iron is increased and the TIBC is normal |
| 17. Anemias of infl ammation/chronic diseases can be caused by A. inflammation B. infection C. malignancy D. all of the above |
| 18. AOI can result from A. inappropriately decreased erythropoietin B. suppression of erythropoiesis by cytokines from activated macrophages and lymphocytes C. impaired iron metabolism D. all of the above |
| 19. The typical peripheral blood fi lm of a patient with AOI typically reveals _____ erythrocytes. A. microcytic, hypochromic B. macrocytic, hypochromic C. normocytic, normochromic D. many spherocytes |
| 20. Leukoerythroblastosis can appear as _____ on a peripheral blood smear. A. immature leukocytes B. immature erythrocytes C. immature thrombocytes D. both A and B |
| 21. What is the most appropriate treatment for AOI? A. Red blood cell transfusion B. Iron therapy C. Erythropoietin injections D. Treatment of the inflammatory condition |
| 22. Sideroblastic anemia can be caused by A. congenital (chromosomal) defect B. drugs (e.g., chloramphenicol) C. association with malignant disorders (e.g., acute myelogenous leukemia) |
| 23. A common feature of sideroblastic anemia is A. ringed sideroblasts B. decreased serum iron C. decreased serum ferritin D. macrocytic red blood cells |
| 24. The greatest portion of operational body iron is normally contained in what compound? A. Hemoglobin B. Ferritin C. Cytochromes |
| 25. Storage iron in the human body is A. found in hepatocytes B. found in macrophages C. sequestered as ferritin D. all of the above |
| 26. The most sensitive assay for the diagnosis of hereditary hemochromatosis (HH) is A. serum iron B. serum iron–binding capacity C. transferrin D. transferrin saturation |
