Home Laboratory QuizzesHaematology Quizzes [MCQs] Leukocytes: The Granulocytic and Monocytic Series

[MCQs] Leukocytes: The Granulocytic and Monocytic Series

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The Granulocytic and Monocytic Series

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The granules of segmented neutrophils contain

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Which of the following are contents of basophilic granules?

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The types of granulocytic leukocytes found in the maturation-storage compartment of the bone marrow are

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The immediate precursor of the macrophage is the

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The hematology tests that are useful in the early diagnosis of acute infl ammation are the

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The tissue basophil can be referred to as a/an

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The correct sequence(s) of events in successful phagocytosis is (are)

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An increase in metamyelocytes, myelocytes, and promyelocytes can be referred to as

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The mononuclear phagocyte system consists of reticular cells. These cells can be found in the

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The mature granulocytes seen in the peripheral blood of healthy persons include

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The principal leukocyte type involved in phagocytosis is the

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The stages of neutrophilic granulocyte development are

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Release of neutrophils from the bone marrow is believed to be influenced by

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The half-life of circulating granulocytes in normal blood is estimated to be

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Identify the cell with these characteristics: prominent primary granules that are rich in myeloperoxidase and chloroacetate esterase and has a diameter of 14 to 20 mm.

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The major function of neutrophilic granulocytes is

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The total leukocyte count can be increased in certain states. Select the conditions when this is not true.

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The CLSI-recommended method for the ESR is the

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The earliest granulocytic maturational stage in which secondary or specifi c granules appear is

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Marginating granulocytes in the peripheral blood can be found

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On the basis of the following data, calculate the absolute value of the segmented neutrophils. Total leukocyte count = 12 × 10^9/L; percentage of segmented neutrophils on the differential count = 80%. The absolute segmented neutrophil value is

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The reference range of PMN neutrophil count in adults is

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What is the normal range of the segmented neutrophil absolute value?

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Acute infl ammation is based on

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Monocytes are capable of

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The granulocyte cells that are believed to descend from a common multipotential stem cell in the bone marrow are

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The major function of eosinophils is

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The types of granulocytic leukocytes found in the proliferative compartment of the bone marrow are

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A leukocyte with the morphological characteristics of being the largest normal mature leukocyte in the peripheral blood and having a convoluted or twisted nucleus is the

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The absolute value of segmented neutrophils can be an unreliable indicator of overwhelming infection because

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The Granulocytic and Monocytic Series
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1. The granulocyte cells that are believed to descend from a common multipotential stem cell in the bone marrow are
A. neutrophils and eosinophils
B. basophils and lymphocytes
C. lymphocytes and monocytes
D. Both A and B
2. The types of granulocytic leukocytes found in the proliferative compartment of the bone marrow are
A. myeloblasts, myelocytes, and metamyelocytes
B. myeloblasts, promyelocytes, and myelocytes
C. myeloblasts, promyelocytes, myelocytes, and metamyelocytes
D. myeloblasts, promyelocytes, myelocytes, metamyelocytes, and band neutrophils
3. The types of granulocytic leukocytes found in the maturation-storage compartment of the bone marrow are
A. metamyelocytes, band form neutrophils, segmented neutrophils, mature eosinophils, and mature basophils
B. only band form neutrophils, segmented neutrophils, mature eosinophils, and mature basophils
C. metamyelocytes, band form neutrophils, segmented neutrophils, mature eosinophils, and mature basophils
D. segmented neutrophils, immature and mature monocytes, and mature lymphocytes
4. Release of neutrophils from the bone marrow is believed to be influenced by
A. CSF
B. interleukins
C. interferon
D. all of the above
5. The stages of neutrophilic granulocyte development are
A. promyelocyte, myeloblast, myelocyte, metamyelocyte, and band and segmented neutrophils
B. myeloblast, promyelocyte, myelocyte, metamyelocyte, and band and segmented neutrophils
C. myelocyte, myeloblast, promyelocyte, metamyelocyte, and band and segmented neutrophils
D. myeloblast, promyelocyte, metamyelocyte, myelocyte, and band and segmented neutrophils
6. Marginating granulocytes in the peripheral blood can be found
A. in the circulating pool
B. in the tissues
C. adhering to the vascular endothelium
D. all of the above
7. The major function of neutrophilic granulocytes is
A. antibody production
B. destruction of parasites
C. phagocytosis
D. suppression of inflammation
8. The half-life of circulating granulocytes in normal blood is estimated to be
A. 2.5 to 5 hours
B. 7 to 10 hours
C. 24 hours
D. 2 days
9. Identify the cell with these characteristics: prominent primary granules that are rich in myeloperoxidase and chloroacetate esterase and has a diameter of 14 to 20 mm.
A. myeloblast
B. promyelocyte
C. myelocyte
D. promonocyte
10. The earliest granulocytic maturational stage in which secondary or specifi c granules appear is
A. myeloblast
B. monoblast
C. promyelocyte
D. myelocyte
11. The mature granulocytes seen in the peripheral blood of healthy persons include
A. band form and segmented neutrophils
B. eosinophils and basophils
C. lymphocytes and monocytes
D. Both A and B
12. The granules of segmented neutrophils contain
A. lysosomal hydrolases
B. lysozymes
C. myeloperoxidase
D. all of the above
13. Which of the following are contents of basophilic granules?
A. Heparin
B. Histamine
C. Myeloperoxidase
D. Both A and B
14. The tissue basophil can be referred to as a/an
A. mast cell
B. macrophage
C. mononuclear cell
D. antibody-producing cell
15. A leukocyte with the morphological characteristics of being the largest normal mature leukocyte in the peripheral blood and having a convoluted or twisted nucleus is the
A. myelocyte
B. metamyelocyte
C. promonocyte
D. monocyte
16. The reference range of PMN neutrophil count in adults is
A. 20 – 40%
B. 40 – 60%
C. 60 – 80%
D. 80 – 100%
17. The principal leukocyte type involved in phagocytosis is the
A. monocyte
B. neutrophil
C. eosinophil
D. basophil
18. The mononuclear phagocyte system consists of reticular cells. These cells can be found in the
A. connective tissue
B. spleen
C. lymph nodes
D. all of the above
19. The immediate precursor of the macrophage is the
A. myeloblast
B. monoblast
C. promonocyte
D. monocyte
20. The correct sequence(s) of events in successful phagocytosis is (are)
A. chemotaxis, opsonization, phagosome formation, and the action of antibacterial substances
B. opsonization, chemotaxis, phagosome formation, and the action of antibacterial substances
C. engulfment, opsonization, digestion, and destruction of bacteria or particulate matter
D. Both A and C
21. The major function of eosinophils is
A. suppression of inflammatory reactions
B. destruction of protozoa
C. participation in anaphylaxis
D. phagocytosis
22. Monocytes are capable of
A. phagocytosis
B. synthesis of biologically important compounds
C. assuming a killer role
D. All of the above
23. The hematology tests that are useful in the early diagnosis of acute infl ammation are the
A. total leukocyte count and total erythrocyte count
B. total leukocyte count and white blood cell differential count
C. ESR and absolute neutrophil cell count
D. Both B and C
24. The total leukocyte count can be increased in certain states. Select the conditions when this is not true.
A. Strenuous exercise
B. Overwhelming bacterial infection
C. Sepsis
D. Use of immunosuppressive agents
25. Acute infl ammation is based on
A. total leukocyte count >10.5 × 109/L
B. neutrophilic band count <2%
C. symptoms of long duration
D. an increase in lymphocytes
26. On the basis of the following data, calculate the absolute value of the segmented neutrophils. Total leukocyte count = 12 × 109/L; percentage of segmented neutrophils on the differential count = 80%. The absolute
segmented neutrophil value is
A. 2.5 × 109/L
B. 4.5 × 109/L
C. 6.5 × 109/L
D. 9.6 × 109/L
27. An increase in metamyelocytes, myelocytes, and promyelocytes can be referred to as
A. leukocytopenia
B. a shift to the right
C. a shift to the left
D. Pelger-Huet anomaly
28. What is the normal range of the segmented neutrophil absolute value?
A. 1.4 to 6 × 109/L
B. 2.5 to 6.5 × 109/L
C. 3.5 to 8 × 109/L
D. 5.5 to 10 × 109/L
29. The absolute value of segmented neutrophils can be an unreliable indicator of overwhelming infection because
A. it drops in many patients because the circulating granulocytes are mobilized into the tissue site of infection
B. the bone marrow reserve becomes exhausted
C. the infection suppresses granulocytic production
D. All of the above
30. The CLSI-recommended method for the ESR is the
A. Wintrobe method
B. Westergren method
C. Duke
D. Ivy

 

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