[MCQ] Polymyositis, Dermatomyositis, and Inclusion Body Myositis

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1 Which of the following is an inflammatory myopathy ?
A. Polymyositis (PM)
B. Dermatomyositis (DM)
C. Inclusion body myositis (IBM)
D. All of the above

2 In inflammatory myopathy, which of the following muscles is not
involved ?
A. Quadriceps muscle
B. Ocular muscles
C. Pharyngeal muscles
D. Neck-flexor muscles

3 Which of the following about inclusion body myositis is false ?
A. Thrice more frequent in men than women
B. May have asymmetric muscle weakness pattern
C. Fine-motor movements affected late in the course
D. Falling is common

4 Extramuscular manifestations are associated with which of the
following inflammatory myopathies ?
A. Polymyositis
B. Dermatomyositis
C. Inclusion Body Myositis
D. All of the above
5 Which of the following is present in polymyositis ?
A. Skin rash
B. Involvement of extraocular & facial muscles
C. Endocrinopathy
D. None of the above

6 Which of the following is a feature of dermatomyositis ?
A. Gottron rash
B. V sign
C. Shawl sign
D. All of the above
7 Most common tumors associated with dermatomyositis (DM)
include all except ?
A. Ovarian cancer
B. Breast cancer
C. Colon cancer
D. Hodgkin lymphoma

8 Which of the following is rare with dermatomyositis (DM) ?
A. Rheumatoid arthritis
B. Systemic lupus erythematosus
C. Sjögren’s syndrome
D. All of the above

9 Patients with overlap syndrome of dermatomyositis and systemic
sclerosis have which antinuclear antibody ?
A. Anti-PM/Scl
B. Anti-IBM/Scl
C. Anti-DM/Scl
D. All of the above

10 Antibody directed against histidyl-transfer RNA synthetase is
called ?
A. Anti-Jo-1 antibody
B. Anti-Ro antibody
C. Anti-Hu antibody
D. Anti-Zic antibody

11 Inflammatory myopathy patients with anti-Jo-1 antibodies have
an increased frequency of ?
A. Interstitial lung disease
B. Raynaud’s phenomenon
C. Nonerosive arthritis
D. All of the above

12 Which of the following is characteristic of polymyositis ?
A. CD4/MHC-I complex
B. CD8/MHC-I complex
C. CD20/MHC-I complex
D. CD28/MHC-I complex

13 Which of the following parasites can lead to inflammatory myopathy
(parasitic polymyositis) ?
A. Toxoplasma
B. Trypanosoma
C. Cysticerci
D. All of the above

14 Tropical polymyositis is produced by ?
A. Parasite
B. Bacteria
C. Virus
D. Toxin

15 Acute painless muscle weakness with myoglobinuria may occur
with ?
A. Hypokalemia
B. Hypophosphatemia
C. Hypomagnesemia
D. Any of the above

16 D-penicillamine is used in which of the following diseases ?
A. Scleroderma
B. Rheumatoid arthritis
C. Primary biliary cirrhosis
D. All of the above

17.amyloid deposits on muscle biopsy are found in ?
A. Polymyositis
B. Dermatomyositis
C. Inclusion Body Myositis
D. All of the above

18. Which of the following drugs produce true myositis resembling
PM ?
A. Amphotericin B
B. Colchicine
C. Procainamide
D. Simvastatin

19. In PM & DM, objective increase in muscle strength occurs how
many months after prednisone treatment ?
A. 1 month
B. 3 months
C. 6 months
D. 12 months

20. Which of the following is ineffective in PM & DM ?
A. Azathioprine
B. Mycophenolate mofetil
C. Intravenous immunoglobulin (IVIg)
D. Plasmapheresis