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Pheochromocytoma- Part 3
See all quizzes of Pheochromocytoma at here:
Pheochromocytoma- Part 1| Pheochromocytoma- Part 2| Pheochromocytoma- Part 3
1.Which of the following is false about pheochromocytoma ?
A. Solitary lesions are right sided
B. Highly vascular
C. Tumors are not innervated
D. None of the above
2. Features that suggest familial pheochromocytoma include ?
A. Bilaterality
B. Multicentricity
C. Age of onset < 30 years
D. All of the above
3. Which of the following is a hypotensive peptide ?
A. Endothelin
B. Adrenomedullin
C. Erythropoietin
D. Neuropeptide Y
4. In pheochromocytoma, elevated level of amylase is due to ?
A. Damaged pulmonary endothelium
B. Associated pancreatitis
C. Sialolithiasis
D. All of the above
5. To assess adequacy of collected urine sample, which of the
following should also be determined ?
A. Urea
B. Creatinine
C. Sodium
D. Potassium
6. Which of the following may cause hypertension & increased
excretion of catecholamines/catecholamine metabolites ?
A. Posterior fossa tumors
B. Subarachnoid hemorrhage
C. Diencephalic or autonomic epilepsy
D. All of the above
7. Which of the following statements is false ?
A. ACTH receptors are located exclusively in adrenal cortex
B. FSH receptors are found only in gonads
C. Insulin & thyroid hormone receptors are widely distributed
D. None of the above
8. Which of the following drugs block catecholamine synthesis ?
A. Doxazosin
B. Methyl-paratyrosine (metirosine)
C. Phenoxybenzamine
D. All of the above
9. Which of the following hormones is proteolytically derived from
larger precursor polypeptides ?
A. PTH
B. Glucagon
C. Insulin
D. All of the above
10. In WDHA syndrome, ‘W’ stands for ?
A. Weight loss
B. Wasting
C. Watery
D. Weakness
11. Which of the following is a part of WDHA syndrome ?
A. Weight loss
B. Dementia
C. Hypokalemia
D. Alkalosis
12. Which of the following is not caused by ‘VIP’ hormone ?
A. Small-intestinal chloride secretion
B. Inhibition of acid secretion
C. Skeletal muscle excitability
D. Vasodilatory effects
13. Which of the following regarding VIPoma’s is false ?
A. Also called Verner-Morrison syndrome
B. Stool volume of < 700 mL/day rules out VIPoma
C. Hyperglycemia & hypercalcemia frequent
D. None of the above
14. Diseases that cause secretory large-volume diarrhea include all
except ?
A. Gastrinomas
B. GRFomas
C. Carcinoid syndrome
D. Systemic mastocytosis
15. Nonfunctional pancreatic endocrine tumours secrete all except ?
A. Chromogranin A
B. Chromogranin B
C. -human chorionic gonadotropin
D. VIP
16. GRFomas are found as ?
A. Pancreatic endocrine tumour
B. Lung tumour
C. Small intestinal carcinoids
D. All of the above
17. Which of the following is false about MEN1 ?
A. Also called Wermer’s syndrome
B. Autosomal recessive
C. Neoplasia of parathyroid, pituitary & pancreatic islet
D. Hyperparathyroidism is most common manifestation
18. Which of the following is false about MEN1 ?
A. Increased urine calcium excretion
B. Serum calcium rarely elevated at birth
C. Parathyroid hyperplasia
D. None of the above
19. Tumor-suppressor protein encoded by MEN1 gene is ?
A. Henin
B. Menin
C. Tenin
D. Senin
20. ‘Pancreatic cholera’ is due to overproduction of ?
A. VIP
B. Gastrin
C. Ghrelin
D. Glucagon
21. Which of the following hormones is most commonly produced
by pituitary tumors in MEN1 ?
A. GH
B. Prolactin
C. ACTH
D. TSH
22. Mutations of which of the following genes occurs in MEN2 ?
A. TERC
B. SPINK5
C. TRIM37
D. RET
23.Which of the following is not a feature of MEN type 2A ?
A. Medullary thyroid carcinoma (MTC)
B. Pheochromocytoma
C. Mucosal neuromas
D. Hyperparathyroidism
24. Which of the following is not a feature of MEN type 2B ?
A. Medullary thyroid carcinoma (MTC)
B. Pheochromocytoma
C. Mucosal neuromas
D. Hyperparathyroidism
25.Subvariant of MEN2A include ?
A. Familial medullary thyroid carcinoma (FMTC)
B. Cutaneous lichen amyloidosis
C. Hirschsprung disease
D. All of the above
