[MCQ] Heart Failure and Cor Pulmonale- Part 2

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Heart Failure and Cor Pulmonale- Part 1 | Heart Failure and Cor Pulmonale- Part 2

1.Natriuretic peptide levels are more in ?
A. Aged
B. Renal impairment
C. Women
D. All of the above

2.  Levels of which of the following may be elevated in HF ?
A. C-reactive protein
B. TNF receptors
C. Uric acid
D. All of the above

3. Loop diuretics increase fractional excretion of sodium by ?
A. 5 – 10 %
B. 10 – 20 %
C. 20 – 25 %
D. 25 – 50 %

4. Which of the following diuretics lead to hyperkalemia ?
Harrison’s 18th Ed. 1907
A. Spironolactone
B. Eplerenone
C. Triamterene
D. All of the above
5. Which of the following can attenuate the effects of ACE inhibitors ?
A. Anxiety
B. Physical exercise
C. Fluid retention
D. All of the above

6.  Monproductive cough as a side effect of ACE inhibitors is related to ?
A. Stimulating guanylyl cyclase
B. Interference with adrenergic nervous system
C. Kinin potentiation
D. All of the above

7.  Which of the following statements about beta blockers in HF is false ?
A. Should be initiated in low doses
B. Upward titration at 2-week intervals
C. Maximum dose as reported effective in clinical trials
D. None of the above
8.  Aldosterone antagonists are not recommended when ?
A. Serum creatinine is > 2.5 mg/dL
B. Creatinine clearance is < 30 mL/minute
C. Serum potassium is > 5 mmol/L
D. Any of the above
9.  Amiodarone increases the level of which of the following ?
A. Phenytoin
B. Digoxin
C. Warfarin
D. All of the above
10.  Which of the following is an adverse effect of amiodarone ?
A. Hyperthyroidism
B. Hypothyroidism
C. Hepatitis
D. All of the above

11.  Which of the following is a precipitating cause of acute decompensated HF (ADHF) ?
A. Infection
B. Pulmonary embolism
C. Occult myocardial ischemia
D. All of the above

12.  Most patients with acute pulmonary edema belong to which of the following profiles ?
A. Profile A
B. Profile B
C. Profile C
D. Profile L

13.  Which of the following drugs exerts dilating effect on arterial resistance and venous capacitance vessels ?
A. Nitroglycerin

B. Nitroprusside
C. Nesiritide
D. All of the above

14.  Cyanide toxicity in nitroprusside therapy occurs at doses ?
A. > 150 µg / minute for over 24 hours
B. > 150 µg / minute for over 48 hours
C. > 250 µg / minute for over 24 hours
D. > 250 µg / minute for over 48 hours

15.  Nesiritide is best related to ?
A. Atrial-type natriuretic peptide
B. Brain-type natriuretic peptide
C. Phosphodiesterase III inhibitor
D. Endogenous catecholamine

16.  Which of the following is an inotropic agent ?
A. Dopamine
B. Dobutamine
C. Tolvaptan
D. All of the above

17.  Which of the following is a phosphodiesterase III inhibitor ?
A. Dopamine
B. Dobutamine
C. Tolvaptan
D. Milrinone

18.  Dopamine stimulates which of the following ?
A. 
1 receptors
B.  1 receptors
C. Dopaminergic receptors
D. All of the above

19.  Which of the following is administered orally ?
A. Nesiritide
B. Nitroprusside
C. Tolvaptan
D. Milrinone

20.  Decompensation of chronic cor pulmonale is aggravated by ?
A. Obesity hypoventilation syndrome (OHS)
B. Acute pulmonary emboli
C. Positive-pressure (mechanical) ventilation
D. All of the above

21.  Most common cause of right-heart failure is ?
A. Pulmonary parenchymal disease
B. Pulmonary vascular disease
C. Left heart failure
D. Any of the above