[MCQ] Evaluation of liver function- Part 1

I. Start the exam by click the “Start” button

See all quizzes of Evaluation of liver function at here:

1.Which of the following liver function tests do not measure liver
function at all ?
A. S. Bilirubin
B. S. Aminotransferases
C. S. Albumin
D. Prothrombin time

2.Isolated elevation of unconjugated bilirubin is seen in ?
A. Hemolytic disorders
B. Crigler-Najjar syndrome
C. Gilbert’s syndrome
D. All of the above

3. Which of the following about Gilbert’s syndrome is false ?
A. Healthy patient
B. Isolated, unconjugated hyperbilirubinemia
C. Absence of hemolysis
D. None of the above
4. Which of the following is elevated in Gilbert’s syndrome ?
A. Aminotransferases
B. Alkaline phosphatase
C. Prothrombin time
D. None of the above

5. In isolated unconjugated hyperbilirubinemia, of the total
bilirubin, the direct bilirubin is ?
A. < 15 %
B. < 20 %
C. < 25 %
D. < 30 %

6. In liver disease, rate-limiting step in bilirubin metabolism is ?
A. Entry of bilirubin in hepatocyte
B. Conjugation of bilirubin in hepatocyte
C. Transport of conjugated bilirubin into bile canaliculi
D. All of the above

7. Which of the following about liver functions is false ?
A. Increased unconjugated bilirubin is rarely due to liver disease
B. Conjugated hyperbilirubinemia almost always implies liver
or biliary tract disease
C. In most liver diseases, both conjugated & unconjugated
bilirubin are elevated
D. None of the above
8. Total serum bilirubin correlates with poor outcomes in ?
A. Viral hepatitis

B. Alcoholic hepatitis
C. Drug-induced liver disease
D. All of the above

9. Bilirubin found in urine is ?
A. Unconjugated
B. Conjugated
C. Unconjugated + conjugated
D. All of the above

10. Which of the following may give a false-positive reading with
Ictotest tablet ?
A. Barbiturates
B. Phenothiazines
C. Antacids
D. NSAID’s

11. Which of the following is true in patients recovering from
jaundice ?
A. Urine bilirubin clears prior to serum bilirubin
B. Serum bilirubin clears prior to urine bilirubin
C. Urine and serum bilirubin clear simultaneously
D. Any of the above

12. Which of the following play a role in detoxification of ammonia ?
A. Spleen
B. Pancreas
C. Striated muscle
D. Cartilage

13. Aspartate aminotransferase (AST) found in all except ?
A. Skeletal muscle
B. Kidneys
C. Spleen
D. Lungs
14. Aspartate aminotransferase (AST) not found in ?
A. Leukocytes
B. Erythrocytes
C. Platelets
D. All of the above

15. Least concentration of AST is in ?
A. Brain
B. Erythrocytes
C. Lungs
D. Pancreas

16. Elevation of aminotransferases to >1000 U/L occurs in which
of the following disorders ?
A. Viral hepatitis
B. Ischemic liver injury
C. Toxin or drug-induced liver injury
D. All of the above

17.What AST:ALT ratio is highly suggestive of alcoholic liver
disease ?
A. > 1.5:1
B. > 2:1
C. > 2.5:1
D. > 3:1

18. Which of the following about alcoholic liver disease is false ?
A. AST rarely > 300 U/L
B. ALT often normal
C. Increase in IgA levels
D. None of the above

19. Which of the following about aminotransferases is false ?
A. Aminotransferases are present in serum in low concentrations
B. Liver cell necrosis not required for release of aminotransferases
C. Absolute elevation of aminotransferases is of no prognostic
significance in acute hepatocellular disorders
D. None of the above