[MCQ] Acute Respiratory Distress Syndrome- Part 1

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Acute Respiratory Distress Syndrome- Part 1

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Congratulations - you have completed Acute Respiratory Distress Syndrome- Part 1. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rated as %%RATING%%

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Question 1

Diagnostic criteria for ARDS is ?

A	PaO2 / FiO2 <=200 mm Hg
B	Acute onset
C	Pulmonary capillary wedge pressure <= 18 mm Hg
D	All of the above

Question 2

Diagnostic criteria for ARDS include all except ?

A	PaO2 / FiO2 <=200 mm Hg
B	PaO2 / FiO2 <=300 mm Hg
C	Acute onset
D	Pulmonary capillary wedge pressure <= 18 mm Hg

Question 2 Explanation:

PaO2 / FiO2 <=300 mm Hg is typical of Acute lung injury (ALI). Acute onset and PCWP <= 18 mm Hg being the same as in ARDS

Question 3

Which of the following is the most common situation leading to ARDS ?

A	Multiple bone fractures
B	Head trauma
C	Burns
D	Near drowning

Question 4

Scores for Acute Physiology, Age, and Chronic Health Evaluation (APACHE II) can range from ?

A	0 to 61
B	0 to 61
C	0 to 81
D	0 to 91

Question 4 Explanation:

Trauma patients with APACHE II score >=16 have a 2.5-fold increase in risk of ARDS. Those with a score >20 have an incidence of ARDS that is 3 fold greater than those with APACHE II scores <=9

Question 5

Phases of ARDS are all except ?

A	Exudative
B	Serofibrinous
C	Serofibrinous
D	Fibrotic

Question 5 Explanation:

Natural history of ARDS, each having its own characteristic clinico-pathologic features is marked by three phases i.e. exudative, proliferative, and fibrotic.

Question 6

Which of the following is a lipid mediator ?

A	Interleukin 1
B	Interleukin 8
C	Tumor necrosis factor α
D	Leukotriene B4

Question 6 Explanation:

Significant concentrations of cytokines (interleukin 1, interleukin 8, and tumor necrosis factor alpha) and lipid mediators (leukotriene B4) are present in the lung in early exudative phase of ARDS.

Question 7

Which of the following is not a feature of exudative phase of ARDS ?

A	Alveolar edema
B	Neutrophil-rich leukocytic infiltration
C	Prominent interstitial inflammation
D	Formation of hyaline membrane whorls

Question 7 Explanation:

Exudative phase is notable for early alveolar edema and neutrophil-rich leukocytic infiltration of the lungs with subsequent formation of hyaline membranes from diffuse alveolar damage

Question 8

Which of the following is not a feature of exudative phase of ARDS ?

A	Injury to alveolar capillary endothelial cells
B	Injury to type I pneumocytes
C	Proliferation of type II pneumocytes
D	Vascular obliteration by microthrombi & fibrocellular proliferation

Question 9

Which of the following is false about early ARDS ?

A	Alveolar edema involves dependent portions of lung
B	Hypercapnia is prominent in early ARDS
C	Chest x-ray in ARDS rarely shows cardiomegaly
D	None of the above

Question 10

After exposure to a precipitating ARDS risk factor, exudative phase encompasses how many days ?

A	First 1 day
B	First 3 days
C	First 5 days
D	First 5 days

Question 10 Explanation:

Exudative phase encompasses first 7 days of illness after exposure to a precipitating ARDS risk factor

Question 11

Chest radiograph in exudative phase of ARDS shows alveolar & interstitial opacities involving ?

A	One-third of lung fields
B	One half of lung fields
C	Two-thirds of lung fields
D	Three-quarters of lung fields

Question 11 Explanation:

CxR in exudative phase of ARDS reveals alveolar & interstitial opacities involving at least threequarters of the lung fields.

Question 12

Chest x-ray in exudative phase of ARDS rarely shows ?

A	Cardiomegaly
B	Pleural effusions
C	Pulmonary vascular redistribution
D	All of the above

Question 12 Explanation:

All of the above

Question 13

In D/D of ARDS, which one of the following is least likely ?

A	Cardiogenic pulmonary edema
B	Hypersensitivity pneumonitis
C	Diffuse pneumonia
D	Alveolar hemorrhage

Question 13 Explanation:

In D/D of ARDS, most common disorders are cardiogenic pulmonary edema, diffuse pneumonia, and alveolar hemorrhage. Less frequent diagnoses include acute interstitial lung diseases, hypersensitivity pneumonitis, radiation pneumonitis and neurogenic pulmonary edema.

Question 14

Proliferative phase of ARDS usually lasts from ?

A	Day 7 to 10
B	Day 7 to 10
C	Day 7 to 18
D	Day 7 to 21

Question 14 Explanation:

Proliferative phase of ARDS usually lasts from day 7 to day 21

Question 15

Histologically, in proliferative phase of ARDS, pulmonary infiltrate is ?

A	Neutrophil predominant
B	Lymphocyte predominant
C	Eosinophil predominant
D	Basophil predominant

Question 15 Explanation:

In proliferative phase of ARDS, first signs of resolution are evident with initiation of lung repair, organization of alveolar exudates & a shift from a neutrophil to a lymphocyte-predominant pulmonary infiltrate.

Question 16

Which of the following represents a reparative process in proliferative phase of ARDS ?

A	Organization of alveolar exudates
B	Lymphocyte-predominant pulmonary infiltrate
C	Proliferation of type II pneumocytes
D	All of the above

Question 16 Explanation:

As part of the reparative process, there is a proliferation of type II pneumocytes along alveolar basement membranes

Question 17

Presence of procollagen III in alveolar space is associated with increased risk of death in patients of ?

A	Pneumoconiosis
B	Pneumoconiosis
C	ARDS
D	All of the above

Question 17 Explanation:

Presence of alveolar type III procollagen peptide (marker of pulmonary fibrosis), is associated with a protracted clinical course & increased mortality from ARDS

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See all quizzes of Acute Respiratory Distress Syndrome at here:

Acute Respiratory Distress Syndrome- Part 1| Acute Respiratory Distress Syndrome- Part 2

1. Diagnostic criteria for ARDS is ?
A. PaO2 / FiO2 <=200 mm Hg
B. Acute onset
C. Pulmonary capillary wedge pressure <= 18 mm Hg
D. All of the above
2. Diagnostic criteria for ARDS include all except ?
A. PaO2 / FiO2 <=200 mm Hg
B. PaO2 / FiO2 <=300 mm Hg
C. Acute onset
D. Pulmonary capillary wedge pressure <= 18 mm Hg

3. Which of the following is the most common situation leading to ARDS ?
A. Multiple bone fractures
B. Head trauma
C. Burns
D. Near drowning

4. Scores for Acute Physiology, Age, and Chronic Health Evaluation (APACHE II) can range from ?
A. 0 to 61
B. 0 to 71
C. 0 to 81
D. 0 to 91

5. Phases of ARDS are all except ?
A. Exudative
B. Serofibrinous
C. Proliferative
D. Fibrotic

6. Which of the following is a lipid mediator ?
A. Interleukin 1
B. Interleukin 8
C. Tumor necrosis factor 
D. Leukotriene B4

7. Which of the following is not a feature of exudative phase of ARDS ?
A. Alveolar edema
B. Neutrophil-rich leukocytic infiltration
C. Prominent interstitial inflammation
D. Formation of hyaline membrane whorls

8. Which of the following is not a feature of exudative phase of ARDS ?
A. Injury to alveolar capillary endothelial cells
B. Injury to type I pneumocytes
C. Proliferation of type II pneumocytes
D. Vascular obliteration by microthrombi & fibrocellular proliferation
9. Which of the following is false about early ARDS ?
A. Alveolar edema involves dependent portions of lung
B. Hypercapnia is prominent in early ARDS
C. Chest x-ray in ARDS rarely shows cardiomegaly
D. None of the above

10. After exposure to a precipitating ARDS risk factor, exudative phase encompasses how many days ?
A. First 1 day
B. First 3 days
C. First 5 days
D. First 7 days

11. Chest radiograph in exudative phase of ARDS shows alveolar & interstitial opacities involving ?
A. One-third of lung fields
B. One half of lung fields
C. Two-thirds of lung fields
D. Three-quarters of lung fields

12. Chest x-ray in exudative phase of ARDS rarely shows ?
A. Cardiomegaly
B. Pleural effusions
C. Pulmonary vascular redistribution
D. All of the above

13. In D/D of ARDS, which one of the following is least likely ?
A. Cardiogenic pulmonary edema
B. Hypersensitivity pneumonitis
C. Diffuse pneumonia
D. Alveolar hemorrhage

14. Proliferative phase of ARDS usually lasts from ?
A. Day 7 to 10
B. Day 7 to 14
C. Day 7 to 18
D. Day 7 to 21

15. Histologically, in proliferative phase of ARDS, pulmonary infiltrate is ?
A. Neutrophil predominant
B. Lymphocyte predominant
C. Eosinophil predominant

16. Which of the following represents a reparative process in proliferative phase of ARDS ?
A. Organization of alveolar exudates
B. Lymphocyte-predominant pulmonary infiltrate
C. Proliferation of type II pneumocytes
D. All of the above

17. Presence of procollagen III in alveolar space is associated with increased risk of death in patients of ?
A. Pneumoconiosis
B. Bronchial asthma
C. ARDS
D. All of the above

Acute Respiratory Distress Syndrome

[MCQ] Acute Respiratory Distress Syndrome- Part 1

I. Start the exam by click the “Start” button

Acute Respiratory Distress Syndrome- Part 1

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