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Rheumatoid Arthritis- Part 3
See all quizzes of Rheumatoid Arthritis- Part 3 here:
1 Additional autoantibodies found in RA are all except ?
A. Antibodies to filaggrin
B. Antibodies to citrullinated proteins
C. Antibodies to calpastatin
D. Antibodies to fibronectin
2 Severe systemic RA disease is reflected by ?
A. PMN leucocytosis
B. Eosinophilia
C. Basophilia
D. Thrombocytosis
3 Acute-phase reactants elevated in RA include ?
A. Erythrocyte sedimentation rate
B. Ceruloplasmin
C. C-reactive protein
D. All of the above
4 Which of the following is the earliest radiological sign in RA ?
A. Soft tissue swelling
B. Juxta-articular osteopenia
C. Loss of articular cartilage
D. Bone erosions
5 Which of the following is the earliest radiological sign in RA ?
A. Formation of spicules
B. Juxta-articular osteopenia
C. Joint effusion
D. Loose bodies
6 Features that correlate with a greater likelihood of developing
joint abnormalities/disabilities in RA include all except ?
A. Presence of more than 10 inflamed joints
B. Markedly elevated erythrocyte sedimentation rate
C. Radiographic evidence of bone erosions
D. Presence of rheumatoid nodules
7 Features that correlate with a greater likelihood of developing
joint abnormalities or disabilities in RA include all except ?
A. High titers of serum rheumatoid factor
B. Early age at onset
C. Low socioeconomic status or education level
D. Presence of HLA-DRB1*0401 or DRB*0404
8 Which of the following does not signify poor prognosis in RA ?
A. High titers of rheumatoid factor
B. High titers of C-reactive protein
C. High titers of haptoglobin
D. High titers of histatin
10 Features of patients with RA that have poor prognostic significance
are all except ?
A. High titers of rheumatoid factor, CRP & haptoglobin
B. Subcutaneous nodules
C. Radiographic evidence of erosions at time of initial evaluation
D. Sustained disease activity of > 6 months duration
11 Factors correlated with early death in RA include ?
A. Disability
B. Age at onset
C. Glucocorticoid use
D. All of the above
12 Median life expectancy of RA patients is shortened by ?
A. Nil
B. 1 – 3 years
C. 3 – 7 years
D. 7 – 10 years
13 Which of the following statements about RA is false ?
A. Foot joints more frequently affected than hand joints
B. Bilateral symmetric inflammatory polyarthritis
C. Involves small & large joints in upper & lower limbs
D. None of the above
14 Which of the following about RA is false ?
A. Sparing of axial skeleton except cervical spine
B. Morning stiffness lasting > 1 hour
C. Presence of subcutaneous nodules is diagnostic
D. None of the above
15 Which of the following about RA is false ?
A. Presence of rheumatoid factor & anti-CCP antibodies
B. Inflammatory synovial fluid with increased PMNLs
C. Juxtaarticular bone demineralization
D. None of the above
16 Molecular mimicry between microbial proteins & host tissues has
been reported in ?
A. Type 1 diabetes mellitus
B. Rheumatoid arthritis
C. Multiple sclerosis
D. All of the above
17 Patients with rheumatoid arthritis have the highest incidence of
infective arthritis most often with ?
A. S. aureus
B. Streptococci
C. Hemophilus
D. Pseudomonas
18 Distal interphalangeal joints are involved in ?
A. Osteoarthritis
B. Psoriatic
C. Reactive
D. All of the above
19 Most common disorder associated with relapsing polychondritis
is ?
A. Systemic vasculitis
B. Rheumatoid arthritis
C. Systemic lupus erythematosus
D. Sjögren’s syndrome
20 Upper airway obstruction in RA is due to ?
A. Cervical spine involvement
B. Muscular atrophy
C. Crico-arytenoid arthritis
D. All of the above
21 In RA, exudative pericardial fluid has ?
A. Decreased concentrations of complement
B. Decreased concentrations of glucose
C. Elevated cholesterol
D. All of the above
22 Which of the following is true about Rheumatoid factor ?
A. Antibody against Fc portion of immunoglobulin A
B. Antibody against Fc portion of immunoglobulin E
C. Antibody against Fc portion of immunoglobulin G
D. All of the above
23 Rheumatoid factor can be detected in ?
A. Malaria
B. Tuberculosis
C. Hepatitis C
D. All of the above
