[MCQ] Tuberculosis- Part 3

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Tuberculosis- Part 3

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Congratulations - you have completed Tuberculosis- Part 3. You scored %%SCORE%% out of %%TOTAL%%. Your performance has been rated as %%RATING%%

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Question 1

In pulmonary TB, detectable rales can be heard over involved areas during inspiration especially after ?

A	Exercise
B	Lying prone
C	Full meal
D	Coughing

Question 1 Explanation:

In pulmonary TB, detectable rales can be heard over involved areas during inspiration especially after coughing

Question 2

In TB, fever is ?

A	Intermittent
B	Remittent
C	Continuous
D	Any of the above

Question 2 Explanation:

In TB, the fever is often low-grade and intermittent in up to 80% of cases.

Question 3

What is Ranke complex ?

A	Healed calcified lesion in lung parenchyma & hilar lymph nodes
B	Fibrocavitatory lung lesion
C	Calcification of pleura
D	None of the above

Question 4

Which is the most commonly involved site in extrapulmonary tuberculosis ?

A	Lymph nodes
B	Pleura
C	Genitourinary tract
D	Bones & joints

Question 5

Out of the following, which is the least commonly involved site in extrapulmonary tuberculosis ?

A	Meninges
B	Pleura
C	Genitourinary tract
D	Bones & joints

Question 6

Out of the following, which is the least commonly involved site in extrapulmonary tuberculosis ?

A	Meninges
B	Peritoneum
C	Genitourinary tract
D	Bones & joints

Question 6 Explanation:

In order of frequency, the extrapulmonary sites most commonly involved in tuberculosis are the lymph nodes, pleura, genitourinary tract, bones and joints, meninges, peritoneum & pericardium

Question 7

In what percentage of tubercular lymph-node biopsy are AFB seen ?

A	25 %
B	50 %
C	80 %
D	100 %

Question 7 Explanation:

In fine-needle aspiration or surgical biopsy of TB lymph node, AFB are seen in up to 80% of cases.

Question 8

Lymph-node tuberculosis most commonly presents at which of the following sites ?

A	Anterior cervical
B	Posterior cervical
C	Axilla
D	Inguinal

Question 8 Explanation:

Lymph-node tuberculosis mostly presents at posterior cervical and supraclavicular sites (scrofula).

Question 9

Features of a typical tuberculous lymphadenitis include ?

A	Caseating epithelioid cell granulomas
B	Langerhans’ giant cells
C	Lymphocytic infiltrates
D	All of the above

Question 9 Explanation:

Features of a typical tuberculous lymphadenitis include areas of tuberculous granulation tissue with full-blown caseating epithelioid cell granulomas, Langerhans’ giant cells & lymphocytic infiltrates.

Question 10

Which of the following about Kikuchi-Fujimoto disease is false ?

A	Necrotizing lymphadenitis
B	Benign, self-limited disease
C	Predominantly in old males
D	Can occur in association with SLE

Question 10 Explanation:

Features of Kikuchi-Fujimoto disease are necrotizing lymphadenitis, benign, self-limited disease, predominantly occurs in young women, presents as fever, cervical lymphadenopathy, and hepatosplenomegaly. It can precede or occur in association with SLE.

Question 11

The only systemic manifestation of Kimura’s disease is ?

A	Cardiac
B	Renal
C	CNS
D	Lung

Question 11 Explanation:

Kimura’s disease is a benign allergic inflammatory disorder of unknown cause endemic in Orientals. Renal involvement is its only systemic manifestation (membranous glomerulonerphritis, minimal change glomerulonephritis, diffuse proliferative glomerulonephritis, mesangial proliferative glomerulonephritis and also nephrotic syndrome). It typically presents as non-tender preauricular & submandibular lymphadenopathy, peripheral eosinophilia and elevated IgE level.

Question 12

Histiocytic necrotizing lymphadenitis is best related to ?

A	Mikulicz’s disease
B	Kimura’s disease
C	Kikuchi-Fujimoto disease
D	Tuberculous lymphadenitis

Question 13

Benign lymphoepithelial lesion is best related to ?

A	Mikulicz’s disease
B	Kimura’s disease
C	Kikuchi-Fujimoto disease
D	Tuberculous lymphadenitis

Question 13 Explanation:

Mikulicz’s disease is a benign lymphoepithelial lesion presenting as benign enlargement of parotid and/or lacrimal glands sometimes associated with Sjögren’s syndrome

Question 14

Angiofollicular hyperplasia is best related to ?

A	Castleman’s disease
B	Mikulicz’s disease
C	Kimura’s disease
D	Kikuchi-Fujimoto disease

Question 14 Explanation:

Castleman’s disease is also referred to as angiofollicular hyperplasia.

Question 15

Human Herpes Virus 8 (HHV8) is associated with ?

A	Kaposi’s sarcoma
B	Primary Effusion lymphoma
C	Multicentric Castleman’s Disease
D	All of the above

Question 15 Explanation:

Human Herpes Virus 8 (HHV8) is associated with Kaposi’s sarcoma, Primary Effusion lymphoma and multicentric Castleman’s Disease.

Question 16

Which of the following about tuberculous pleural fluid is false ?

A	WBC count usually 500 to 6000/μL
B	Protein concentration > 50 % of that in serum
C	Normal to low glucose concentration
D	pH generally > 7.4

Question 16 Explanation:

The tubercular pleural fluid is an exudate with a protein concentration >50% of that in serum, a normal to low glucose concentration, pH ~ 7.3, and detectable WBC (500 to 6000/μL).

Question 17

Which of the following cells is rare in tuberculous pleural fluid ?

A	Neutrophils
B	Mononuclear cells
C	Mesothelial cells
D	All of the above

Question 17 Explanation:

In tuberculous pleural fluid, neutrophils may predominate in early stage. Later, mononuclear cells are the typical finding. Mesothelial cells are generally rare or absent.

Question 18

Which of the following about tuberculous empyema is true ?

A	Due to rupture of a tubercular cavity into pleural space
B	Due to a bronchopleural fistula from pulmonary lesion
C	May result in restrictive lung disease
D	All of the above

Question 18 Explanation:

Tuberculous empyema is the result of rupture of a tubercular cavity into pleural space, or of a bronchopleural fistula from a pulmonary lesion. It may result in severe pleural fibrosis & restrictive lung disease.

Question 19

Tuberculosis of upper airways is a complication of ?

A	Hematogenous spread
B	Scrofula
C	Advanced cavitary pulmonary TB
D	Any of the above

Question 19 Explanation:

Tuberculosis of upper airways is a complication is nearly always a complication of advanced cavitary pulmonary tuberculosis. It may involve larynx, pharynx and epiglottis

Question 20

Which of the following suggest tuberculosis as a cause of genitourinary disease ?

A	Culture-negative pyuria in acidic urine
B	Calcifications and ureteral strictures on IVP
C	Preferential involvement of epididymis
D	All of the above

Question 20 Explanation:

Calcifications and ureteral strictures on IVP and documentation of culture-negative pyuria in acidic urine raises the suspicion of tuberculosis

Question 21

In males, genital tuberculosis preferentially affects which of the following ?

A	Epididymis
B	Testes
C	Prostate
D	All of the above

Question 21 Explanation:

In male patients, tuberculosis preferentially affects the epididymis which may form an external fistula. Orchitis and prostatitis may also develop.

Question 22

In skeletal tuberculosis, which of the following is most frequently affected ?

A	Spine
B	Hip joint
C	Knee joint
D	Ankle joint

Question 22 Explanation:

Weight-bearing joints are affected most commonly in skeletal tuberculosis. Involvement of spine is more frequent than hip and knee.

Question 23

Most common site of spinal tuberculosis in adults is ?

A	Cervical
B	Upper thoracic
C	Lower thoracic
D	Lower lumbar

Question 23 Explanation:

In children, upper thoracic spine is the most common site of spinal tuberculosis. Lower thoracic and upper lumbar vertebrae are usually affected in adults.

Question 24

Of the extrapulmonary TB cases in US, which is the least frequent ?

A	Genitourinary tuberculosis
B	Tuberculosis of bones & joints
C	Lymph-node tuberculosis
D	Gastrointestinal tuberculosis

Question 24 Explanation:

Lymph-node tuberculosis >40%, TB involvement of pleura ~20%, Genitourinary tuberculosis ~15%, Tuberculosis of bones & joints ~10%, Gastrointestinal tuberculosis 3.5%, Tuberculosis of CNS ~5%.

Question 25

Pathogenetic mechanism of gastrointestinal tuberculosis is ?

A	Swallowing of sputum with direct seeding
B	Hematogenous spread
C	Ingestion of milk from tubercular cows
D	All of the above

Question 25 Explanation:

Pathogenetic mechanism of gastrointestinal tuberculosis may be swallowing of sputum with direct seeding, hematogenous spread or ingestion of milk from cows with bovine tuberculosis.

Question 26

With intestinal-wall involvement in tuberculosis, the presentation may simulate which of the following ?

A	Ulcerative colitis
B	Amoebic colitis
C	Appendicitis
D	Crohn’s disease

Question 26 Explanation:

With intestinal-wall involvement in tuberculosis, ulcerations & fistulae may simulate Crohn’s disease.

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See all quizzes of Tuberculosis- Part 3 here:

1 In pulmonary TB, detectable rales can be heard over involved
areas during inspiration especially after ?
A. Exercise
B. Lying prone
C. Full meal
D. Coughing

2 In TB, fever is ?
A. Intermittent
B. Remittent
C. Continuous
D. Any of the above

3 What is Ranke complex ?
A. Healed calcified lesion in lung parenchyma & hilar lymph nodes
B. Fibrocavitatory lung lesion
C. Calcification of pleura
D. None of the above
4 Which is the most commonly involved site in extrapulmonary
tuberculosis ?
A. Lymph nodes
B. Pleura
C. Genitourinary tract
D. Bones & joints
5 Out of the following, which is the least commonly involved site
in extrapulmonary tuberculosis ?
A. Meninges
B. Pleura
C. Genitourinary tract
D. Bones & joints
6 Out of the following, which is the least commonly involved site
in extrapulmonary tuberculosis ?
A. Meninges
B. Peritoneum
C. Genitourinary tract
D. Bones & joints

7 In what percentage of tubercular lymph-node biopsy are AFB
seen ?
A. 25 %
B. 50 %
C. 80 %
D. 100 %

8 Lymph-node tuberculosis most commonly presents at which of
the following sites ?
A. Anterior cervical
B. Posterior cervical
C. Axilla
D. Inguinal

9 Features of a typical tuberculous lymphadenitis include ?
A. Caseating epithelioid cell granulomas
B. Langerhans’ giant cells
C. Lymphocytic infiltrates
D. All of the above

10 Which of the following about Kikuchi-Fujimoto disease is false ?
A. Necrotizing lymphadenitis
B. Benign, self-limited disease
C. Predominantly in old males
D. Can occur in association with SLE

11 The only systemic manifestation of Kimura’s disease is ?
A. Cardiac
B. Renal
C. CNS
D. Lung

12 Histiocytic necrotizing lymphadenitis is best related to ?
A. Mikulicz’s disease
B. Kimura’s disease
C. Kikuchi-Fujimoto disease
D. Tuberculous lymphadenitis
13 Benign lymphoepithelial lesion is best related to ?
A. Mikulicz’s disease
B. Kimura’s disease
C. Kikuchi-Fujimoto disease
D. Tuberculous lymphadenitis

14 Angiofollicular hyperplasia is best related to ?
A. Castleman’s disease
B. Mikulicz’s disease
C. Kimura’s disease
D. Kikuchi-Fujimoto disease

15 Human Herpes Virus 8 (HHV8) is associated with ?
A. Kaposi’s sarcoma
B. Primary Effusion lymphoma
C. Multicentric Castleman’s Disease
D. All of the above

16 Which of the following about tuberculous pleural fluid is false ?
A. WBC count usually 500 to 6000/μL
B. Protein concentration > 50 % of that in serum
C. Normal to low glucose concentration
D. pH generally > 7.4

17 Which of the following cells is rare in tuberculous pleural fluid ?
A. Neutrophils
B. Mononuclear cells
C. Mesothelial cells
D. All of the above

18 Which of the following about tuberculous empyema is true ?
A. Due to rupture of a tubercular cavity into pleural space
B. Due to a bronchopleural fistula from pulmonary lesion
C. May result in restrictive lung disease
D. All of the above

19 Tuberculosis of upper airways is a complication of ?
A. Hematogenous spread
B. Scrofula
C. Advanced cavitary pulmonary TB
D. Any of the above

20 Which of the following suggest tuberculosis as a cause of
genitourinary disease ?
A. Culture-negative pyuria in acidic urine
B. Calcifications and ureteral strictures on IVP
C. Preferential involvement of epididymis
D. All of the above

21 In males, genital tuberculosis preferentially affects which of the
following ?
A. Epididymis
B. Testes
C. Prostate
D. All of the above

22 In skeletal tuberculosis, which of the following is most frequently
affected ?
A. Spine
B. Hip joint
C. Knee joint
D. Ankle joint

23 Most common site of spinal tuberculosis in adults is ?
A. Cervical
B. Upper thoracic
C. Lower thoracic
D. Lower lumbar

24 Of the extrapulmonary TB cases in US, which is the least
frequent ?
A. Genitourinary tuberculosis
B. Tuberculosis of bones & joints
C. Lymph-node tuberculosis
D. Gastrointestinal tuberculosis

25 Pathogenetic mechanism of gastrointestinal tuberculosis is ?
A. Swallowing of sputum with direct seeding
B. Hematogenous spread
C. Ingestion of milk from tubercular cows
D. All of the above

26 With intestinal-wall involvement in tuberculosis, the presentation
may simulate which of the following ?
A. Ulcerative colitis
B. Amoebic colitis
C . Appendicitis
D. Crohn’s disease

Tuberculosis

[MCQ] Tuberculosis- Part 3

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Tuberculosis- Part 3

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