I. Start the exam by click the “Start” button
ENZYMES- Part 5
See all quizzes of ENZYMES- Part 5 here:
1. In the erythrocytes, the net production of
ATP molecules by the Rapport-Leubering
pathway is
(A) 0 (B) 2
(C) 4 (D) 8
2. The ratio that most closely approximates
the number of net molecules of ATP
formed per mole of glucose utilized under
aerobic conditions to the net number
formed under anaerobic conditions is
(A) 4:1 (B) 13:1
(C) 18:1 (D) 24:1
3. The pathway of glycogen biosynthesis
involves a special nucleotide of glucose.
In the reaction below, NuDP stands for
NuDP Glucose + glycogenn → NuDP + glycogenn+1
(A) ADP (B) GDP
(C) UDP (D) CDP
4. Glucose 6-phosphate is converted to glucose
1-phosphate in a reaction catalysed
by the enzyme phosphoglucomutase,
which is
(A) Phosphorylated
(B) Dephosphorylated
(C) Phosphorylated-dephosphorylated
(D) Phosphorylated-dephosphorylatedrephosphorylated
5. The glycogen content of the liver is upto
(A) 6% (B) 8%
(C) 10% (D) 12%
6. In glycogenesis a branch point in the
molecule is established by the enzyme
(A) Amylo[1→ 4][1→ 6] transglucosidase
(B) α [1→ 4] α [1→ 4] Glucan transferase
(C) Amylo [1→ 6] glucosidase
(D) Glycogen synthase
7. In glycogenolysis, the enzyme which
transfers a trisaccharide unit from one
branch to the other exposing 1→ 6 branch
point is
(A) Phosphorylase
(B) α-[1→ 4]→ α-[1→ 4]→ Glucan transferase
(C) Amylo [1→ 6] glucosidase
(D) Amylo[1→ 4]→ [1→ 6] transglucosidase
8. In the synthesis of glycogen from glucose
the reversible step is
(A) Glucose → glucose 6-phosphate
(B) Glucose 6-phosphate → glucose 1-phosphate
(C) Glucose 1-phosphate → UDP glucose
(D) UDP glucose → glycogen
9. The enzyme glucose-6-phosphatase
which catalyses the conversion of glucose
6-phosphate to glucose is not found in
(A) Liver (B) Muscle
(C) Intestine (D) Kidney
10. Allosteric activator of glycogen synthase
is
(A) Glucose (B) Glucose-6-Phosphate
(C) UTP (D) Glucose-1-phosphate
11. Action of glycogen synthase is inhibited by
(A) Insulin (B) Glucose
(C) Mg2+ (D) Cyclic AMP
12. The hormone activating the glycogen
synthase activity is
(A) Insulin (B) Glucagon
(C) Epinephrine (D) ACTH
13. Characteristic features of active site are
(A) Flexible in nature (B) Site of binding
(C) Acidic (D) Both (A) and (B)
14. Von Gierke’s disease is characterized by
the deficiency of
(A) Glucose-6-phosphatase
(B) α -1 → 4 Glucosidase
(C) 1 → 6 Glucosidase
(D) Liver phosphorylase
15. Cori disease (Limit dextrinosis) is caused
due to absence of
(A) Branching enzyme
(B) Debranching enzyme
(C) Glycogen synthase
(D) Phosphorylase
16. Mc Ardle’s syndrome is characterized by
the absence of
(A) Liver phosphorylase
(B) Muscle phosphorylase
(C) Branching enzyme
(D) Debranching enzyme
17. Pompe’s disease is caused due to
deficiency of
(A) Lysosomal α-1→4 and 1→6-glucosidase
(B) Glucose-6-phosphatase
(C) Glycogen synthase
(D) Phosphofructokinase
18. Amylopectinosis is caused due to absence
of
(A) Debranching enzyme
(B) Branching enzyme
(C) Acid maltase
(D) Glucose-6-phosphatase
19. Her’s disease is characterized by deficiency
of
(A) Muscle phosphorylase
(B) Liver phosphorylase
(C) Debranching enzyme
(D) Glycogen synthase
20. Tarui disease is characterized by the
deficiency of the enzyme:
(A) Liver phosphorylase
(B) Muscle phosphorylase
(C) Muscle and erythrocyte phosphofructokinase
(D) Lysosomal acid maltase
21. The hexose monophosphate pathway
includes the enzyme:
(A) Maltase dehydrogenase
(B) Hexokinase
(C) α-Ketoglutarate dehydrogenase
(D) Glucose-6-phosphate dehydrogenase
22. The hydrogen acceptor used in pentose
phosphate pathway is
(A) NAD (B) NADP
(C) FAD (D) FMN
23. The enzymes of the pentose phosphate
pathway are found in the
(A) Cytosol
(B) Mitochondria
(C) Nucleus
(D) Endoplasmic reticulum
24. In pentose phosphate pathway, D-ribulose-
5-phosphate is converted to D-ribose-5-
phosphate by the enzyme:
(A) Fumarase (B) Ketoisomerase
(C) G-6-PD (D) Epimerase
25. The transketolase enzyme in the pentose
phosphate pathway requires the B
vitamin.
(A) Pantothenic acid (B) Thiamin
(C) Riboflavin (D) Nicotinic acid
26. Xylulose-5-phosphate serves as a donar
of active glycolaldehyde, the acceptor is
(A) Erythrose 4-phosphate
(B) Ribose 5-phosphate
(C) Glyceraldehyde 3-phosphate
(D) Sedoheptulose 7-phosphate
27. Pentose phosphate pathway is of significance
because it generates
(A) NADPH for reductive synthesis
(B) Regenerates glucose 6-phosphate
(C) Generates fructose 6-phosphate
(D) Forms glyceraldehyde 3-phosphate
28. The pentose phosphate pathway protects
erythrocytes against hemolysis by assisting
the enzyme:
(A) Superoxide dismutase
(B) Catalase
(C) Glutathionic peroxidase
(D) Cytochrome oxidase
29. Hemolytic anemia is caused by the
deficiency of certain enzymes of the
pentose phosphate pathway, the
principal enzyme involved is
(A) Glucose-6-phosphate dehydrogenase
(B) Aldolase
(C) Fructose 1, 6-bisphosphatase
(D) Phosphohexose isomerase
30. The sites for gluconeogenesis are
(A) Liver and kidney
(B) Skin and pancreas
(C) Lung and brain
(D) Intestine and lens of eye
