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HORMONE METABOLISM- Part 2
See all quizzes of HORMONE METABOLISM- Part 2 here:
1 One of the potent stimulators of
aldosterone secretion is
(A) Increased sodium concentration
(B) Decreased potassium concentration
(C) Increased potassium concentration
(D) Increased ECF volume
2. In the rennin-angiotensin system the
primary hormone is
(A) Angiotensinogen (B) Angiotensin I
(C) Angiotensin II (D) Angiotensin III
3. Aldosterone release is stimulated by
(A) α2-Globulin (B) Renin
(C) Angiotensin II (D) Growth hormone
4. In the synthesis of Angiotensin I, rennin
acts on Angiotensinogen and cleaves the
(A) Leucine – leucine at 10 and 11 position
(B) Valine – tyrosine at 3 and 4 position
(C) Isoleucine – histidine at 5 and 6 position
(D) Proline – histidine at 7 and 8 position
5. Catecholamine hormones are synthesized
in the
(A) Chromaffin cells of adrenal medulla
(B) Zona glomerulosa of adrenal cortex
(C) Zona fasciculate of adrenal cortex
(D) Zona reticularis of adrenal cortex
6. Catecholamine hormones are
(A) 3, 4-Dihydroxy derivatives of phenylethylamine
(B) p-Hydroxy derivatives of phenylacetate
(C) p-Hydroxy derivatives of phenylpyruvate
(D) p-Hydroxy derivatives of phenyllactate
7. The sequential steps in the conversion of
tyrosine to epinephrine are
(A) Ring hydroxylation-decarboxylation-side chain
hydroxylation-N-methylation
(B) Side chain hydroxylation-decarboxylation-ring
hydroxylation N-methylation
(C) Decarboxylation-ring hydroxylation-side chain
hydroxylation-N-methylation
(D) N-methylation-decarboxylation-ring and side
chain hydroxylation
8. The hormone required for uterine muscle
contraction for child birth is
(A) Progesterone (B) Estrogen
(C) Oxytocin (D) Vasopressin
9. The number of amino acids in the hormone
oxytocin is
(A) 7 (B) 9
(C) 14 (D) 18
10. Vasopressin and oxytocin circulate unbound
to proteins and have very short
plasma half lives, on the order of
(A) 1–2 minutes (B) 2–4 minutes
(C) 5–8 minutes (D) 10–12 minutes
11. Melanogenesis is stimulated by
(A) MSH (B) FSH
(C) LH (D) HCG
12. The number of amino acids in antidiuretic
hormone is
(A) 9 (B) 18
(C) 27 (D) 36
13. ADH
(A) Reabsorbs water from renal tubules
(B) Excretes water from renal tubules
(C) Excretes hypotonic urine
(D) Causes low specific gravity of urine
14. Increased reabsorption of water from the
kidney is the major consequence of the
secretion of the hormone?
(A) Cortisol (B) Insulin
(C) Vasopressin (D) Aldosterone
15. An increase in the osmolality of extracellular
compartment will
(A) Inhibit ADH secretion
(B) Stimulate ADH secretion
(C) Cause no change in ADH secretion
(D) Stimulate the volume and osmoreceptor and
inhibit ADH secretion
16. For Catecholamine biosynthesis the rate
limiting enzyme is
(A) DOPA decarboxylase
(B) DOPAMINE β-hydroxylase
(C) Tyrosine hydroxylase
(D) Phenylalanine hydroxylase
17. A hormone which cannot cross the blood
brain barrier is
(A) Epinephrine (B) Aldosterone
(C) ACTH (D) TSH
18. The plasma level of epinephrine is less
than
(A) 0.1 ng/ml (B) 0.2 ng/ml
(C) 0.4 ng/ml (D) 0.8 ng/ml
19. Epinephrine is rapidly metabolized by
(A) Monoamine oxidase
(B) Deaminase
(C) Transminase
(D) Decarboxylase
20. Pheochromocytomas are tumours of
(A) Adrenal cortex (B) Adrenal medulla
(C) Pancreas (D) Bone
21. A characteristic of pheochromocytoma is
elevated urinary excretion of
(A) Dopamine
(B) Tyrosine
(C) Vinylmandelic acid
(D) Phenylalanine
22. In the synthetic pathway of epinephrine,
disulfiram (antabuse) inhibits the
enzyme:
(A) Tyrosine hydroxylase
(B) Dopamine β-hydroxylase
(C) DOPA decarboxylase
(D) N-methyl transferase
23. The biosynthesis of both Catecholamine
and serotonin require
(A) Tyrosine hydroxylase
(B) N-methyl transferase
(C) Aromatic amino acid decarboxylase
(D) Tryptophan pyrrolase
24. Epinephrine stimulates glycogenolysis in
(A) Liver (B) Muscle
(C) Liver and muscle (D) Kidney
25. A cup of strong coffee would be expected
to
(A) Interfere with the synthesis of prostaglandins
(B) Decrease the effect of glucagon
(C) Enhance the effect of epinephrine
(D) Provide the vitamin nicotinic acid
26. Epinephrine is derived from norepinephrine
by
(A) Decarboxylation (B) Hydroxylation
(C) Oxidation (D) N-methylation
27. 5 HIAA test is negative if patient is taking
(A) Aspirin (B) Colchicine
(C) Phenothiazone (D) Methotrexate
28. Presence of significant amount of 5-HIAA
in urine indicates
(A) Carcinoid in liver
(B) Carcinoid in appendix
(C) Metastasis of carcinoma of liver
(D) Hepatoma
29. The normal serum level of triiodothyronine
(T3) is
(A) 0.2–0.5 ng/ml (B) 0.7–2.0 ng/ml
(C) 2.0–4.0 ng/ml (D) 5.0–8.0 ng/ml
30. The normal serum level of thyroxine (T4)
is
(A) 2.0–4.0 μg/100 ml
(B) 5.5–13.5 μg/100 ml
(C) 14.0–20.3 μg/100 ml
(D) 20.0–25.0 μg/100 ml
