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PROTEINS AND PROTEIN METABOLISM- Part 21
See all quizzes of PROTEINS AND PROTEIN METABOLISM- Part 21 here:
1 In human and other ureotelic organisms,
the end product of amino acid nitrogen
metabolism:
(A) Bile acids (B) Ketone bodies
(C) Urea (D) Barium sulphate
2. The end product of amino acid nitrogen
metabolism in uricotelic organisms
(reptiles and birds) is
(A) Bilirubin (B) Urea
(C) Uric acid (D) Biliverdin
3. The transaminase activity needs the
coenzyme:
(A) ATP (B) B6 – PO4
(C) FAD+ (D) NAD+
4. Transamination is a
(A) Irreversible process(B) Reversible process
(C) Both (A) and (B) (D) None of these
5. Most amino acids are substrates for
transamination except
(A) Alanine (B) Threonine
(C) Serine (D) Valine
6 Oxidative conversion of many amino
acids to their corresponding -ketoacids
occurs in mammalian:
(A) Liver and kidney (B) Adipose tissue
(C) Pancreas (D) Intestine
7. The α-ketoacid is decarboxylated by H2O2
forming a carboxylic acid with one carbon
atom less in the absence of the enzyme:
(A) Catalase (B) Decarboxylase
(C) Deaminase (D) Phosphatase
8. The activity of mammalian L-amino acid
oxidase, an FMN – flavo protein, is quite
(A) Slow (B) Rapid
(C) Both (A) and (B) (D) None of these
9. From dietary protein as well as from the
urea present in fluids secreted into the
gastrointestinal tract intestinal bacteria
produce
(A) Carbondioxide
(B) Ammonia
(C) Ammonium sulphate
(D) Creatine
10. The symptom of ammonia intoxication
includes
(A) Blurring of vision (B) Constipation
(C) Mental confusion (D) Diarrhoea
11. Ammonia intoxication symptoms occur
when brain ammonia levels are
(A) Slightly diminished (B) Highly diminished
(C) Increased (D) All of these
12. Ammonia production by the kidney is
depressed in
(A) Acidosis (B) Alkalosis
(C) Both (A) and (B) (D) None of these
13. Ammonia is excreted as ammonium salts
during metabolic acidosis but the majority
is excreted as
(A) Phosphates (B) Creatine
(C) Uric acid (D) Urea
14. Synthesis of glutamine is accompanied
by the hydrolysis of
(A) ATP (B) ADP
(C) TPP (D) Creatin phosphate
15. In brain, the major metabolism for
removal of ammonia is the formation of
(A) Glutamate (B) Aspartate
(C) Asparagine (D) Glutamine
16. Carbamoyl phosphate synthetase structure
is marked by change in the presence
of
(A) N-Acetyl glutamate
(B) N-Acetyl Aspartate
(C) Neuraminic acid
(D) Oxalate
17. The biosynthesis of Urea occurs mainly in
the Liver:
(A) Cytosol
(B) Microsomes
(C) Nucleus
(D) Mitochondria
18. One mol. of Urea is synthesized at the
expense of the _______ mols. of ATP.
(A) 2 (B) 3
(C) 4 (D) 5
19. Urea biosynthesis occurs mainly in the
liver involving the number of amino acids:
(A) 3 (B) 4
(C) 5 (D) 6
20. The normal daily output of Urea through
urine in grams:
(A) 10 to 20 (B) 15 to 25
(C) 20 to 30 (D) 25 to 35
21. In severe acidosis, the output of urea is
(A) Decreased (B) Slightly increased
(C) Highly increased (D) Moderately increased
22. Uremia occurs in
(A) Cirrhosis of the liver(B) Nephritis
(C) Diabetes mellitus (D) Coronary thrombosis
23. Clinical symptom in urea cycle disorder is
(A) Mental retardation (B) Drowsiness
(C) Diarrhoea (D) Oedema
24. The sparing action of methionine is
(A) Tyrosine (B) Cystine
(C) Arginine (D) Tryptophan
25. NH+4 aminates glutamate to form
glutamine requiring ATP and
(A) K+ (B) Na+
(C) Ca++ (D) Mg++
26. Glutathione is a
(A) Dipeptide (B) Tripeptide
(C) Polypeptide (D) None of these
27. All following are conjugated proteins
except
(A) Nucleoproteins (B) Proteoses
(C) Metalloproteins (D) Flavoproteins
28. All α-amino acids have one asymmetric
carbon atom except
(A) Arginine (B) Glycine
(C) Aspartic acid (D) Histidine
29. Number of amino acids present in plants,
animals and microbial proteins:
(A) 20 (B) 80
(C) 150 (D) 200
30. Hydrated density of (HD) lipoproteins is
(A) 0.94 gm/ml
(B) 0.94-1.006 gm/ml
(C) 1.006-1.063 gm/ml
(D) 1.063-1.21 gm
