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PROTEINS AND PROTEIN METABOLISM- Part 13
See all quizzes of PROTEINS AND PROTEIN METABOLISM- Part 13 here:
1 All of the following statements about
pancreatic somatostain are true except
(A) It is secreted by δ cells of islets of Langerhans
(B) It stimulates the secretion of gastrin
(C) It inhibits the secretion of secretin
(D) It inhibits the secretion of cholecystokininpancreozymin
2. Histidine is converted into histamine by
(A) Carboxylation (B) Decarboxylation
(C) Methylation (D) Hydroxylation
3. Histamine is synthesised in
(A) Brain (B) Mast cells
(C) Basophils (D) All of these
4. Histamine causes all the following except
(A) Stimulation of gastric secretion
(B) Vasoconstriction
(C) Pruritus
(D) Increase in capillary permeability
5. H2-receptors are blocked by
(A) Diphenhydramine (B) Mepayramine
(C) Pyrilamine (D) Cimetidine
6. Serotonin is synthesised from
(A) Serine (B) Phenylalanine
(C) Tyrosine (D) Tryptophan
7. All the following statements about
serotonin are true except
(A) It causes vasolidatation
(B) It causes bronchoconstriction
(C) It is metabolized by monoamine oxidase
(D) Its metabolite is 5-hydroxyindole acetic acid
8. All the following statements about
angiotensin are true except
(A) Its precursor is an α2-globulin
(B) Its active form is an octapeptide
(C) It is a vasodilator
(D) It increases the secretion of aldosterone
9. Methyl dopa decreases blood pressure by
(A) Inhibiting the synthesis of catecholamines
(B) Antagonising the action of aldosterone
(C) Stimulating the release of renin
(D) Inhibiting the breakdown of angiotensin
10. Binding of gamma-aminobutyric acid to
its receptors in brain increases the
permeability of cell membrane to
(A) Cl– (B) Na+
(C) K+ (D) Ca++
11. Binding of acetylcholine to its receptors
increases the permeability of cell
membrane to
(A) Ca++ (B) Na+
(C) K+ (D) Na+ and K+
12. All of the following are glycoproteins
except
(A) Collagen (B) Albumin
(C) Transferrin (D) IgM
13. Sialic acids are present in
(A) Proteoglycans (B) Glycoproteins
(C) Both (A) and (B) (D) None of these
14. Hyaluronidase hydrolyses
(A) Hyaluronic acid
(B) Chondroitin sulphate
(C) Heparin
(D) Hyaluronic acid and chondroitin sulphate
15. The most abundant protein in bones is
(A) Collagen type I
(B) Collagen type II
(C) Collagen type III
(D) Non-collagen proteins
16. The most abundant collagen in cartilages
is
(A) Type I (B) Type II
(C) Type III (D) Type IV
17. Collagen and elastin have the following
similarity:
(A) Both are triple helices
(B) Both have hydroxyproline residues
(C) Both have hydrolysine residues
(D) Both are glycoproteins
18. Abnormal collagen structure is seen in all
of the following except
(A) I-cell disease
(B) Osteogenesis imperfecta
(C) Menke’s disease
(D) Ehlers-Danlos sydrome
19. I-cell disease results from absence of the
following from lysosomal enzymes:
(A) Signal sequence
(B) Mannose-6-phosphate
(C) Sialic acid
(D) A serine residue
20. In I-cell disease, lysosomal enzymes
(A) Are not synthesised
(B) Are inactive
(C) Lack signal sequence
(D) Cannot reach lysosomes
21. Renal glycosuria occurs due to
(A) Increased filtration of glucose in glomeruli
(B) Increased secretion of glucose by renal
tubular cells
(C) Decreased reabsorption of glucose by renal
tubular cells
(D) Increased conversion of glycogen into glucose
in tubular cells
22. Haematuria can occur in
(A) Haemolytic anaemia
PROTEINS AND PROTEIN METABOLISM 49
(B) Mismatched blood transfusion
(C) Yellow fever
(D) Stone in urinary tract
23. Haematuria can occur in all of the following
except
(A) Acute glomerulonephritis
(B) Cancer of urinary tract
(C) Stone in urinary tract
(D) Mismatched blood transfusion
24. Chyluria can be detected by addition of
the following to the urine:
(A) Sulphosalicylic acid (B) Nitric acid
(C) Acetic anhydride (D) Chloroform
25. Normal range of serum urea is
(A) 0.6–1.5 mg/dl (B) 9–11 mg/dl
(C) 20–45 mg/dl (D) 60–100 mg/dl
26. Normal range of serum creatinine is
(A) 0.6–1.5 mg/dl (B) 9–11 mg/dl
(C) 20–45 mg/dl (D) 60–100 mg/dl
27. Standard urea clearance is
(A) 54 ml/min (B) 75 ml/min
(C) 110 ml/min (D) 130 ml/min
28. Maximum urea clearance is
(A) 54 ml/min (B) 75 ml/min
(C) 110 ml/min (D) 130 ml/min
29. Average creatinine clearance in an adult
man is about
(A) 54 ml/min (B) 75 ml/min
(C) 110 ml/min (D) 130 ml/min
30. Inulin clearance in an average adult man
is about
(A) 54 ml/min (B) 75 ml/min
(C) 110 ml/min (D) 130 ml/min
