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FATS AND FATTY ACID METABOLISM- Part 9
See all quizzes of FATS AND FATTY ACID METABOLISM- Part 9 here:
1 Sphingomyelins:
(A) Phospholipids (B) Nitrolipids
(C) Alcohols (D) None of these
2. All of the following statements about
hypoglycin are true except
(A) It is a plant toxin
(B) It causes hypoglycaemia
(C) It inhibits oxidation of short chain fatty acids
(D) It inhibits oxidation of long chain fatty acids
3. Synthesis of prostaglandins is inhibited
by
(A) Glucocorticoids (B) Aspirin
(C) Indomethacin (D) All of these
4. Lipo-oxygenase is required for the synthesis
of
(A) Prostaglandins (B) Leukotrienes
(C) Thromboxanes (D) All of these
5. All of the following statements about
multiple sclerosis are true except
(A) There is loss of phospholipids from white matter
(B) There is loss of sphingolipids from white matter
(C) There is loss of esterified cholesterol from white
matter
(D) White matter resembles gray matter in
composition
6. After entering cytosol, free fatty acids are
bound to
(A) Albumin (B) Globulin
(C) Z-protein (D) None of these
7. Release of free fatty acids from adipose
tissue is increased by all of the following
except
(A) Glucagon (B) Epinephrine
(C) Growth hormone (D) Insulin
8. All the following statements about brown
adipose tissue are true except
(A) It is rich in cytochromes
(B) It oxidizes glucose and fatty acids
(C) Oxidation and phosphorylation are tightly
coupled in it
(D) Dinitrophenol has no effect on it
9. Lovastatin and mevastatin lower
(A) Serum triglycerides
(B) Serum cholesterol
(C) Serum phospholipids
(D) All of these
10. Lovastatin is a
(A) Competitive inhibitor of acetyl CoA carboxylase
(B) Competitive inhibitor of HMG CoA synthetase
(C) Non-competitive inhibitor of HMG CoA
reductase
(D) Competitive inhibitor of HMG CoA reductase
11. Abetalipoproteinaemia occurs due to a
block in the synthesis of
(A) Apoprotein A (B) Apoprotein B
(C) Apoprotein C (D) Cholesterol
12. All of the following statements about
Tangier disease are true except
(A) It is a disorder of HDL metabolism
(B) Its inheritance is autosomal recessive
(C) Apoproteins A-I and A-II are not synthesised
(D) Plasma HDL is increased
13. Genetic deficiency of lipoprotein lipase
causes hyperlipoproteinaemia of following
type:
(A) Type I (B) Type IIa
(C) Type IIb (D) Type V
14. Chylomicrons are present in fasting
blood samples in hyperlipoproteinaemia
of following types:
(A) Types I and IIa (B) Types IIa and IIb
(C) Types I and V (D) Types IV and V
15. Glutathione is a constituent of
(A) Leukotriene A4 (B) Thromboxane A1
(C) Leukotriene C4 (D) None of these
16. Prostaglandins are inactivated by
(A) 15-Hydroxyprostaglandin dehydrogenase
(B) Cyclo-oxygenase
(C) Lipo-oxygenase
(D) None of these
17. Phenylbutazone and indomethacin
inhibit
(A) Phospholipase A1 (B) Phospholipase A2
(C) Cyclo-oxygenase (D) Lipo-oxygenase
18. Prostaglandins stimulate
(A) Aggregation of platelets
(B) Lipolysis in adipose tissue
(C) Bronchodilatation
(D) Gastric acid secretion
19. For extramitochondrial fatty acid synthesis,
acetyl CoA may be obtained from
(A) Citrate (B) Isocitrate
(C) Oxaloacetate (D) Succinate
20. Fluidity of membranes is increased by
the following constituent except
(A) Polyunsaturated fatty acids
(B) Saturated fatty acids
(C) Integral proteins
(D) Cholesterol
21. Transition temperature of membranes
may be affected by the following constituent
of membranes:
(A) Peripheral proteins (B) Integral proteins
(C) Cholesterol (D) Oligosachharides
22. Acetyl CoA formed from pyruvate can be
used for the synthesis of all the following
except
(A) Glucose (B) Fatty acids
(C) Cholesterol (D) Steroid hormones
23. Which of the following can be used as a
source of energy in extrahepatic tissues?
(A) Acetoacetate (B) Acetone
(C) Both (A) and (B) (D) None of these
24. Anti-inflammatory corticosteroids inhibit
(A) Phospholipase A1 (B) Phospholipase A2
(C) Cyclo-oxygenase (D) Lipo-oxygenase
25. Cyclo-oxygenase is involved in the
synthesis of
(A) Prostaglandins (B) Thromboxanes
(C) Both (A) and (B) (D) None of these
26. Leukotrienes cause
(A) Increase in capillary permeability
(B) Aggregation of platelets
(C) Bronchodilatation
(D) None of these
27. Prostaglandins decrease all of the following
except
(A) Gastric acid secretion
(B) Blood pressure
(C) Uterine contraction
(D) Platelet aggregation
28. Hypocholesterolaemia can occur in
(A) Hyperthyroidism
(B) Nephrotic syndrome
(C) Obstructive jaundice
(D) Diabetes mellitus
29. De novo synthesis and oxidation of fatty
acids differ in the following respect:
(A) Synthesis occurs in cytosol and oxidation in
mitochondria
(B) Synthesis is decreased and oxidation
increased by insulin
(C) NADH is required in synthesis and FAD in
oxidation
(D) Malonyl CoA is formed during oxidation but
not during synthesis
30. Free fatty acids released from adipose
tissue are transported in blood by
(A) Albumin (B) VLDL
(C) LDL (D) HDL
