I. Start the exam by click the “Start” button
FATS AND FATTY ACID METABOLISM- Part 8
See all quizzes of FATS AND FATTY ACID METABOLISM- Part 8 here:
1 Salivary lipase converts dietary triglycerides
into
(A) Diglycerides and fatty acids
(B) Monoglycerides and fatty acids
(C) Glycerol and fatty acids
(D) All of these
2. Pancreatic lipase requires for its activity:
(A) Co-lipase (B) Bile salts
(C) Phospholipids (D) All of these
3. Pancreatic lipase converts triacylglycerols
into
(A) 2, 3-Diacylglycerol
(B) 1-Monoacylglycerol
(C) 2-Monoacylglycerol
(D) 3-Monoacylglycerol
4. Oxidation of fatty acids occurs
(A) In the cytosol
(B) In the matrix of mitochondria
(C) On inner mitochondrial membrane
(D) On the microsomes
5. Activation of fatty acids requires all the
following except
(A) ATP (B) Coenzyme A
(C) Thiokinase (D) Carnitine
6. Mitochondrial thiokinase acts on
(A) Short chain of fatty acids
(B) Medium chain fatty acids
(C) Long chain fatty acids
(D) All of these
7. Carnitine is required for the transport of
(A) Triglycerides out of liver
(B) Triglycerides into mitochondria
(C) Short chain fatty acids into mitochondria
(D) Long chain fatty acids into mitochondria
8. Carnitine acylcarnitine translocase is
present
(A) In the inner mitochondrial membrane
(B) In the mitochondrial matrix
(C) On the outer surface of inner mitochondrial
membrane
(D) On the inner surface of inner mitochondrial
membrane
9. Net ATP generation on complete oxidation
of stearic acid is
(A) 129 (B) 131
(C) 146 (D) 148
10. Propionyl CoA formed oxidation of fatty
acids having an odd number of carbon
atoms is converted into
(A) Acetyl CoA
(B) Acetoacetyl CoA
(C) D-Methylmalonyl CoA
(D) Butyryl CoA
11. α-Oxidation of fatty acids occurs mainly in
(A) Liver (B) Brain
(C) Muscles (D) Adipose tissue
12. Refsum’s disease results from a defect in
the following pathway except
(A) Alpha-oxidation of fatty acids
(B) Beta-oxidation of fatty acids
(C) Gamma-oxidation of fatty acids
(D) Omega-oxidation of fatty acids
13. The end product of omega-oxidation of
fatty acids having an even number of
carbon atoms is
(A) Adipic acid (B) Suberic acid
(C) Both (A) and (B) (D) None of these
14. De novo synthesis of fatty acids is
catalysed by a multi-enzyme complex
which contains
(A) One-SH group (B) Two-SH groups
(C) Three-SH groups (D) Four-SH groups
15. Fat depots are located in
(A) Intermuscular connective tissue
(B) Mesentary
(C) Omentum
(D) All of these
16. Salivary lipase is secreted by
(A) Parotid glands
(B) Sub-maxillary glands
(C) Dorsal surface of tongue
(D) None of these
17. Co-lipase is a
(A) Bile salt (B) Vitamin
(C) Protein (D) Phospholipid
18. Plasma becomes milky
(A) Due to high level of HDL
(B) Due to high level of LDL
(C) During fasting
(D) After a meal
19. Mitochondrial membrane is permeable to
(A) Short chain fatty acids
(B) Medium chain fatty acids
(C) Long chain fatty acids
(D) All of these
20. During each cycle of β-oxidation
(A) One carbon atom is removed from the
carboxyl end of the fatty acid
(B) One carbon atom is removed from the methyl
end of the fatty acid
(C) Two carbon atoms are removed from the
carboxyl end of the fatty acid
(D) Two carbon atoms are removed from the
methyl end of the fatty acid
21. Net generation of energy on complete
oxidation of palmitic acid is
(A) 129 ATP equivalents
(B) 131 ATP equivalents
(C) 146 ATP equivalents
(D) 148 ATP equivalents
22. Net generation of energy on complete
oxidation of a 17-carbon fatty acid is
(A) Equal to the energy generation from a
16-carbon fatty acid
(B) Equal to the energy generation from an
18-carbon fatty acid
(C) Less than the energy generation from a
16-carbon fatty acid
(D) In between the energy generation from a
16-carbon fatty acid and an 18-carbon fatty
acid
23. Net energy generation on complete
oxidation of linoleic acid is
(A) 148 ATP equivalents
(B) 146 ATP equivalents
(C) 144 ATP equivalents
(D) 142 ATP equivalents
24. Extramitochondrial synthesis of fatty
acids occurs in
(A) Mammary glands (B) Lungs
(C) Brain (D) All of these
25. One functional sub-unit of multi-enzyme
complex for de novo synthesis of fatty
acids contains
(A) One —SH group
(B) Two —SH groups
(C) Three —SH groups
(D) Four —SH groups
26. NADPH required for fatty acid synthesis
can come from
(A) Hexose monophosphate shunt
(B) Oxidative decarboxylation of malate
(C) Extramitochondrial oxidation of isocitrate
(D) All of these
27. Fatty liver may be prevented by all of the
following except
(A) Choline (B) Betaine
(C) Methionine (D) Ethionine
28. Human desaturase enzyme system
cannot introduce a double bond in a fatty
acid beyond
(A) Carbon 9 (B) Carbon 6
(C) Carbon 5 (D) Carbon 3
29. Which of the following lipid is absorbed
actively from intestines?
(A) Glycerol
(B) Cholesterol
(C) Monoacylglycerol
(D) None of these
30. C22 and C24, fatty acids required for the
synthesis of sphingolipids in brain are
formed by
(A) De novo synthesis
(B) Microsomal chain elongation
(C) Mitochondrial chain elongation
(D) All of these
