[Immunology] The Autoimmunity Quizzes (12 tests)

All of the following may contribute to autoimmunity except

clonal deletion of self-reactive T cells.

molecular mimicry.

new expression of class II MHC antigens.

polyclonal activation of B cells.

Correct! Wrong!

Which of the following would be considered an organspecific autoimmune disease?

SLE

Hashimoto’s thyroiditis

Goodpasture’s syndrome

Correct! Wrong!

SLE can be distinguished from RA on the basis of which of the following?

Joint pain

Presence of antinuclear antibodies

Immune complex formation with activation of complement

Presence of anti-ds DNA antibodies

Correct! Wrong!

Which of the following would support a diagnosis of drug-induced lupus?

Antihistone antibodies

Antibodies to Smith antigen

Presence of RF

Antibodies to SS-A and SS-B antigens

Correct! Wrong!

A homogeneous pattern of staining of the nucleus on IIF may be caused by which of the following antibodies?

Anti-Sm antibody

Anti-SSA/Ro antibody

Antihistone antibody

Anti–double-stranded DNA

Correct! Wrong!

Which of the following is characteristic of RA?

Association with certain HLA-DR genes

Joint involvement that is symmetric

Presence of antibody against IgG

All of the above

Correct! Wrong!

Which of the following best describes the slide agglutination test for RF?

It is specific for RA

A negative test rules out the possibility of RA.

It is a sensitive screening tool.

It detects IgG made against IgM

Correct! Wrong!

Hashimoto’s thyroiditis can best be differentiated from Graves’ disease on the basis of which of the following?

Decrease in thyroid hormone levels

Presence of thyroid peroxidase antibodies

Enlargement of the thyroid

Presence of lymphocytes in the thyroid

Correct! Wrong!

Which of the following would be considered a significant finding in Graves’ disease?

Increased TSH levels

Antibody to TSHR

Decreased T3 and T4

Antithyroglobulin antibody

Correct! Wrong!

Immunologic findings in type I diabetes mellitus include all of the following except

presence of CD8 T cells in the islets of Langerhans.

antibody to colloid.

antibody to insulin.

antibody to GAD.

Correct! Wrong!

Destruction of the myelin sheath of axons caused by the presence of antibody is characteristic of which disease?

Graves’ disease

Goodpasture’s syndrome

Correct! Wrong!

Blood was drawn from a 25-year-old woman with suspected SLE. A FANA screen was performed, and a speckled pattern resulted. Which of the following actions should be taken next?

Report out as diagnostic for SLE

Report out as drug-induced lupus

Perform an antibody profile

Repeat the test

Correct! Wrong!

[Immunology] The Autoimmunity Quizzes (12 tests)

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[Immunology] The Autoimmunity Quizzes (12 tests)

All of the following may contribute to autoimmunity except

Which of the following would be considered an organspecific autoimmune disease?

SLE can be distinguished from RA on the basis of which of the following?

Which of the following would support a diagnosis of drug-induced lupus?

A homogeneous pattern of staining of the nucleus on IIF may be caused by which of the following antibodies?

Which of the following is characteristic of RA?

Which of the following best describes the slide agglutination test for RF?

Hashimoto’s thyroiditis can best be differentiated from Graves’ disease on the basis of which of the following?

Which of the following would be considered a significant finding in Graves’ disease?

Immunologic findings in type I diabetes mellitus include all of the following except

Destruction of the myelin sheath of axons caused by the presence of antibody is characteristic of which disease?

Blood was drawn from a 25-year-old woman with suspected SLE. A FANA screen was performed, and a speckled pattern resulted. Which of the following actions should be taken next?

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