[Immunology] Hypersensitivity Quizzes (14 tests)

Which of the following is a general characteristic of hypersensitivity reactions?

Immune responsiveness is depressed.

Antibody is involved in all reactions.

Either self-antigen or heterologous antigen may be involved.

The antigen triggering the reaction is a harmful one.

Correct! Wrong!

Which of the following is associated with an increase in IgE production?

Transfusion reaction

Activation of Th1 cells

Reaction to poison ivy

HDN

Correct! Wrong!

Which of the following would cause a positive DAT test?

Presence of IgG on red cells

Presence of C3b or C3d on red cells

A transfusion reaction due to preformed antibody

Any of the above

Correct! Wrong!

All of the following are associated with type I hypersensitivity except

release of preformed mediators from mast cells.

activation of complement.

cell-bound antibody bridged by antigen.

an inherited tendency to respond to allergens.

Correct! Wrong!

Which newly synthesized mediator has a mode of action similar to that of histamine?

LTB4

Heparin

ECF-A

PGD2

Correct! Wrong!

Which of the following is associated with anaphylaxis?

Buildup of IgE on mast cells

Activation of complement

Increase in cytotoxic T cells

Large amount of circulating IgG

Correct! Wrong!

To determine if a patient is allergic to rye grass, the best test to perform is

total IgE testing.

skin prick test.

DAT.

complement fixation.

Correct! Wrong!

Which condition would result in HDN?

Buildup of IgE on mother’s cells

Sensitization of cytotoxic T cells

Exposure to antigen found on both mother and baby red cells

Prior exposure to foreign red cell antigen

Correct! Wrong!

What is the immune mechanism involved in type III hypersensitivity reactions?

Cellular antigens are involved.

Deposition of immune complexes occurs in antibody excess.

Only heterologous antigens are involved.

Tissue damage results from exocytosis.

Correct! Wrong!

What is the immune phenomenon associated with the Arthus reaction?

Tissue destruction by cytotoxic T cells

Removal of antibody-coated red blood cells

Deposition of immune complexes in blood vessels

Release of histamine from mast cells

Correct! Wrong!

Contact dermatitis can be characterized by all of the following except

formation of antigen–antibody complexes.

generation of sensitized T cells.

Langerhans cells acting as antigen-presenting cells.

complexing of a hapten to self-antigen.

Correct! Wrong!

Which of the following conclusions can be drawn about a patient whose total IgE level is determined to be 150 IU/mL?

The patient definitely has allergic tendencies.

The patient may be subject to anaphylactic shock.

Further antigen-specific testing should be done.

The patient will never have an allergic reaction.

Correct! Wrong!

Which of the following explains the difference between type II and type III hypersensitivity reactions?

Type II involves cellular antigens.

Type III involves IgE.

IgG is involved only in type III reactions.

Type II reactions involve no antibody

Correct! Wrong!

A 37-year-old woman received two units of packed red blood cells following a surgical procedure. She had been transfused once before. Five days after surgery, she experienced a slight fever and some hemoglobin in her urine, indicating a delayed transfusion reaction. A DAT test on a blood sample was positive. Which of the following statements best describes this reaction?

The patient had IgM antibody to the red cells transfused.

The patient’s reaction was due to an amnestic response.

Only IgE was coating the transfused red blood cells.

The antibody present reacted best at room temperature.

Correct! Wrong!

[Immunology] Hypersensitivity Quizzes (14 tests)

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[Immunology] Hypersensitivity Quizzes (14 tests)

Which of the following is a general characteristic of hypersensitivity reactions?

Which of the following is associated with an increase in IgE production?

Which of the following would cause a positive DAT test?

All of the following are associated with type I hypersensitivity except

Which newly synthesized mediator has a mode of action similar to that of histamine?

Which of the following is associated with anaphylaxis?

To determine if a patient is allergic to rye grass, the best test to perform is

Which condition would result in HDN?

What is the immune mechanism involved in type III hypersensitivity reactions?

What is the immune phenomenon associated with the Arthus reaction?

Contact dermatitis can be characterized by all of the following except

Which of the following conclusions can be drawn about a patient whose total IgE level is determined to be 150 IU/mL?

Which of the following explains the difference between type II and type III hypersensitivity reactions?

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