Antibody Structure and Function Quizzes (16 tests)

Which is characteristic of variable domains of immunoglobulins?

They occur on both the H and L chains.

They represent the complement binding site.

They are at the carboxy-terminal ends of the molecules.

All of the above

Correct! Wrong!

All of the following are true of IgM except that it

can cross the placenta.

fixes complement.

has a J chain.

is a primary response antibody.

Correct! Wrong!

How many antigen binding sites does a typical IgM molecule have?

Correct! Wrong!

Bence-Jones proteins are identical to which of the following?

H chains

L chains

IgM molecules

IgG molecules

Correct! Wrong!

An Fab fragment consists of

two H chains

two L chains.

one L chain and one-half of an H chain.

one L chain and an entire H chain.

Correct! Wrong!

Which of the following pairs represents two different immunoglobulin allotypes?

IgM and IgG

IgM1 and IgM2

Antihuman IgM and antihuman IgG

IgG1m3 and IgG1m17

Correct! Wrong!

Which of the following are L chains of antibody molecules?

Correct! Wrong!

If the results of serum protein electrophoresis show a significant decrease in the gamma band, which of the following is a likely possibility?

Normal response to active infection

Muliple myeloma

Immunodeficiency disorder

Monoclonal gammopathy

Correct! Wrong!

The subclasses of IgG differ mainly in

the type of L chain.

the arrangement of disulfide bonds.

the ability to act as opsonins.

molecular weight.

Correct! Wrong!

Which best describes the role of the SC of IgA?

A transport mechanism across endothelial cells

A means of joining two IgA monomers together

An aid to trapping antigen

Enhancement of complement fixation by the classical pathway

Correct! Wrong!

Which represents the main function of IgD?

Protection of the mucous membranes

Removal of antigens by complement fixation

Enhancing proliferation of B cells

Destruction of parasitic worms

Correct! Wrong!

Which antibody is best at agglutination and complement fixation?

IgA

IgG

IgD

IgM

Correct! Wrong!

Which of the following can be attributed to the clonal selection theory of antibody formation?

Plasma cells make generalized antibody.

B cells are preprogrammed for specific antibody synthesis.

Proteins can alter their shape to conform to antigen.

Cell receptors break off and become circulating antibody.

Correct! Wrong!

All of the following are true of IgE except that it

fails to fix complement.

is heat stable

attaches to tissue mast cells.

is found in the serum of allergic persons.

Correct! Wrong!

Which best describes coding for immunoglobulin molecules?

All genes are located on the same chromosome.

L chain rearrangement occurs before H chain rearrangement.

Four different regions are involved in coding of H chains.

λ rearrangement occurs before ƙ rearrangement.

Correct! Wrong!

What is the purpose of HAT medium in the preparation of monoclonal antibody?

Fusion of the two cell types

Restricting the growth of unfused myeloma cells

Restricting the growth of unfused spleen cells

Restricting antibody production to the IgM class

Correct! Wrong!

Antibody Structure and Function Quizzes (16 tests)

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Antibody Structure and Function Quizzes (16 tests)

Which is characteristic of variable domains of immunoglobulins?

All of the following are true of IgM except that it

How many antigen binding sites does a typical IgM molecule have?

Bence-Jones proteins are identical to which of the following?

An Fab fragment consists of

Which of the following pairs represents two different immunoglobulin allotypes?

Which of the following are L chains of antibody molecules?

If the results of serum protein electrophoresis show a significant decrease in the gamma band, which of the following is a likely possibility?

The subclasses of IgG differ mainly in

Which best describes the role of the SC of IgA?

Which represents the main function of IgD?

Which antibody is best at agglutination and complement fixation?

Which of the following can be attributed to the clonal selection theory of antibody formation?

All of the following are true of IgE except that it

Which best describes coding for immunoglobulin molecules?

What is the purpose of HAT medium in the preparation of monoclonal antibody?

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