Nature of Antigens and the Major Histocompatibility Complex Quizzes (10 questions)

All of the following are characteristic of a good immunogen except

internal complexity

large molecular weight.

the presence of numerous epitopes.

found on host cells.

Correct! Wrong!

Which of the following best describes a hapten?

Not able to react with antibody

Antigenic only when coupled to a carrier

Has multiple determinant sites

A large chemically complex molecule

Correct! Wrong!

Which would be the best immunogen?

Protein with a molecular weight of 200,000

Nylon

Polysaccharide with a molecular weight of 250,000

Protein with a molecular weight of 175,000

Correct! Wrong!

All of the following describe an epitope except

same as an antigenic determinant site.

area of an immunogen recognized by T cells.

consists of sequential amino acids only.

key portion of the immunogen

Correct! Wrong!

Adjuvents act by which of the following methods?

Complex to antigen to increase its size

Prevent rapid escape from the tissues

Increase processing of antigen

All of the above

Correct! Wrong!

A heterophile antigen is one that

is a self-antigen.

exists in unrelated plants or animals.

has been used previously to stimulate antibody response.

is from the same species but is different from the host.

Correct! Wrong!

Which of the following is true of MHC (HLA) class II antigens?

They are found on all nucleated cells.

They are found on B cells and macrophages.

They all originate at one locus.

They are coded for on chromosome 9.

Correct! Wrong!

MHC molecules are associated with which of the following?

Graft rejection

Autoimmune diseases

Determining to which antigens an individual responds

All of the above

Correct! Wrong!

Which of the following best describes the role of TAP?

They bind to class II molecules to help block the antigen-binding site.

They bind to class I proteins in proteosomes.

They transport peptides into the lumen of the endoplasmic reticulum.

They help cleave peptides for transport to endosomes.

Correct! Wrong!

An individual is recovering from a bacterial infection and tests positive for antibodies to a protein normally found in the cytoplasm of this bacterium. Which of the following statements is true of this situation?

Class I molecules have presented bacterial antigen to CD8 T cells.

Class I molecules have presented bacterial antigen to CD4 T cells.

Class II molecules have presented bacterial antigen to CD4 T cells.

B cells have recognized bacterial antigen without help from T cells.

Correct! Wrong!

Nature of Antigens and the Major Histocompatibility Complex Quizzes (10 questions)

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Nature of Antigens and the Major Histocompatibility Complex Quizzes (10 questions)

All of the following are characteristic of a good immunogen except

Which of the following best describes a hapten?

Which would be the best immunogen?

All of the following describe an epitope except

Adjuvents act by which of the following methods?

A heterophile antigen is one that

Which of the following is true of MHC (HLA) class II antigens?

MHC molecules are associated with which of the following?

Which of the following best describes the role of TAP?

An individual is recovering from a bacterial infection and tests positive for antibodies to a protein normally found in the cytoplasm of this bacterium. Which of the following statements is true of this situation?

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