I. Start the exam by click the “Start” button
NUCLEIC ACIDS- Part 2
See all quizzes of NUCLEIC ACIDS- Part 2 here:
1 Transfer RNAs are classified on the basis
of the number of base pairs in
(A) Acceptor arm (B) Anticodon arm
(C) D arm (D) Extra arm
2. In tRNA molecule D arm is named for the
presence of the base:
(A) Uridine (B) Pseudouridine
(C) Dihydrouridine (D) Thymidine
3. The acceptor arm in the tRNA molecule has
(A) 5 Base pairs (B) 7 Base pairs
(C) 10 Base pairs (D) 20 Base pairs
4. In tRNA molecule, the anticodon arm
possesses
(A) 5 Base pairs (B) 7 Base pairs
(C) 8 Base pairs (D) 10 Base pairs
5. The T ψ C arm in the tRNA molecule
possesses the sequence
(A) T, pseudouridine and C
(B) T, uridine and C
(C) T, dihydrouridine and C
(D) T, adenine and C
6. Double helical structure model of the DNA
was proposed by
(A) Pauling and Corey
(B) Peter Mitchell
(C) Watson and Crick
(D) King and Wooten
7. DNA does not contain
(A) Thymine (B) Adenine
(C) Uracil (D) Deoxyribose
8. The sugar moiety present in DNA is
(A) Deoxyribose (B) Ribose
(C) Lyxose (D) Ribulose
9. DNA rich in A-T pairs have
(A) 1 Hydrogen bond (B) 2 Hydrogen bonds
(C) 3 Hydrogen bonds(D) 4 Hydrogen bonds
10. In DNA molecule
(A) Guanine content does not equal cytosine content
(B) Adenine content does not equal thymine content
(C) Adenine content equals uracil content
(D) Guanine content equals cytosine content
11. DNA rich in G-C pairs have
(A) 1 Hydrogen bond (B) 2 Hydrogen bonds
(C) 3 Hydrogen bonds (D) 4 Hydrogen bonds
12. The fact that DNA bears the genetic
information of an organism implies that
(A) Base composition should be identical from
species to species
(B) DNA base composition should charge with
age
(C) DNA from different tissues in the same
organism should usually have the same base
composition
(D) DNA base composition is altered with
nutritional state of an organism
13. The width (helical diameter) of the double
helix in B-form DNA in nm is
(A) 1 (B) 2
(C) 3 (D) 4
14. The number of base pair in a single turn
of B-form DNA about the axis of the
molecule is
(A) 4 (B) 8
(C) 10 (D) 12
15. The distance spanned by one turn of Bform
DNA is
(A) 1.0 nm (B) 2.0 nm
(C) 3.0 nm (D) 3.4 nm
16. In a DNA molecule the thymine concentration
is 30%, the guanosine concentration
will be
(A) 10% (B) 20%
(C) 30% (D) 40%
47. IN a DNA molecule, the guanosine content
is 40%, the adenine content will be
(A) 10% (B) 20%
(C) 30% (D) 40%
18. An increased melting temperature of duplex
DNA results from a high content of
(A) Adenine + Guanine
(B) Thymine + Cytosine
(C) Cytosine + Guanine
(D) Cytosine + Adenine
19. A synthetic nucleotide analogue, 4-hydroxypyrazolopyrimidine
is used in the
treatment of
(A) Acute nephritis
(B) Gout
(C) Cystic fibrosis of lung
(D) Multiple myeloma
10. A synthetic nucleotide analogue, used in
the chemotherapy of cancer and viral
infections is
(A) Arabinosyl cytosine
(B) 4-Hydroxypyrazolopyrimidine
(C) 6-Mercaptopurine
(D) 6-Thioguanine
11. Histamine is formed from histidine by the
enzyme histidine decarboxylase in the
presence of
(A) NAD (B) FMN
(C) HS-CoA (D) B6-PO4
12. Infantile convulsions due to lesser
formation of gamma amino butyric acid
from glutamic acid is seen in the deficiency
of
(A) Glutamate-dehydrogenase
(B) Pyridoxine
(C) Folic acid
(D) Thiamin
23. Which of the following amino acids produce
a vasoconstrictor on decarboxylation?
(A) Histidine (B) Tyrosine
(C) Threonine (D) Arginine
24. The degradation of RNA by pancreatic
ribonuclease produces
(A) Nucleoside 2-Phosphates
(B) Nucleoside 5′-phosphates
(C) Oligonucleosides
(D) Nucleoside 3′-phosphate and oligonucleotide
25. Intestinal nucleosidases act on nucleosides
and produce
(A) Purine base only (B) Phosphate only
(C) Sugar only (D) Purine or pyrimidine
bases and sugars
26. In purine biosynthesis carbon atoms at 4
and 5 position and N at 7 position are
contributed by
(A) Glycine (B) Glutamine
(C) Alanine (D) Threonine
27. N10-formyl and N5N10-methenyl tetrahydrofolate
contributes purine carbon atoms
at position
(A) 4 and 6 (B) 4 and 5
(C) 5 and 6 (D) 2 and 8
28. In purine nucleus nitrogen atom at 1
position is derived from
(A) Aspartate (B) Glutamate
(C) Glycine (D) Alanine
29. The key substance in the synthesis of
purine, phosphoribosyl pyrophosphate is
formed by
(A) α-D-ribose 5-phosphate
(B) 5-phospho β-D-ribosylamine
(C) D-ribose
(D) Deoxyribose
30. In purine biosynthesis ring closure in the
molecule formyl glycinamide ribosyl-5-
phosphate requires the cofactors:
(A) ADP (B) NAD
(C) FAD (D) ATP and Mg++
