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MINERAL METABOLISM- Part 9
See all quizzes of MINERAL METABOLISM- Part 9 here:
1. In thalassemia, an amino acid is substituted
in
(A) Alpha chain
(B) Beta chain
(C) Alpha and beta chains
(D) Any chain
2. Haem synthetase is congenitally deficient
in
(A) Congenital erythropoietic porphyria
(B) Protoporphyria
(C) Hereditary coproporphyria
(D) Variegate porphyria
3. During breakdown of haem, the methenyl
bridge between the following two pyrrole
rings is broken:
(A) I and II (B) II and III
(C) III and IV (D) IV and I
4. Pre- hepatic jaundice occurs because of
(A) Increased haemolysis
(B) Liver damage
(C) Biliary obstruction
(D) None of these
5. kernicterus can occur in
(A) Haemolytic jaundice
(B) Hepatic jaundice
(C) Obstructive jaundice
(D) All of these
6. Bile pigments are not present in urine in
(A) Haemolytic jaundice
(B) Hepatic jaundice
(C) Obstructive jaundice
(D) Rotor’s syndrome
7. Serum alkaline phosphatase is greatly
increased in
(A) Haemolytic jaundice
(B) Hepatic jaundice
(C) Obstructive jaundice
(D) None of these
8. The active transport system for hepatic
uptake of bilirubin is congenitally
defective in
(A) Gilbert’s disease
(B) Crigler-Najjar syndrome
(C) Rotor’s syndrome
(D) Dubin-Johnson syndrome
9. Bilirubin UDP-glucuronyl transferase is
absent from liver in
(A) Crigler-Najjar syndrome, type I
(B) Gilbert’s disease
(C) Crigler-Najjar syndrome, type II
(D) Rotor’s syndrome
10. Unconjugated bilirubin in serum is
soluble in
(A) Water (B) Alkalis
(C) Acids (D) Methanal
11. Excretion of conjugated bilirubin from liver
cells into biliary canaliculi is defective in
(A) Gilbert’s disease
(B) Crigler-Najjar syndrome
(C) Lucey-Driscoll syndrome
(D) Rotor’s syndrome
12. Breakdown of 1gm haemoglobin produces
(A) 20 mg of bilirubin (B) 35 mg of bilirubin
(C) 50 mg of bilirubin (D) 70 mg of bilirubin
13. Variable regions are present in
(A) Immunoglobulins
(B) α-Chains of T cell receptors
(C) β-Chains of T cell receptors
(D) All of these
14. The total amount of calcium in an average
adult man is about
(A) 100 gm (B) 500 gm
(C) 1 kg (D) 10 kg
15. The following proportion of the total body
calcium is present in bones and teeth:
(A) 75% (B) 90%
(C) 95% (D) 99%
16. The normal range of plasma calcium is
(A) 3-5 mg/dl (B) 5-10 mg/dl
(C) 9-11 mg/dl (D) 11-15 mg/dl
17. Which of the normal range of ionized
calcium in plasma is
(A) 2-4 mg/dl (B) 2-4 mEq/L
(C) 4-5 mg/dl (D) 4-5 mEq/L
18. Tetany can occur in
(A) Hypocalcaemia
(B) Hypercalcaemia
(C) Alkalosis
(D) Hypocalcaemia and alkalosis
19. Intestinal absorption of calcium occurs by
(A) Active takeup
(B) Simple diffusion
(C) Facilitated diffusion
(D) Endocytosis
20. Intestinal absorption of calcium is
hampered by
(A) Phosphate (B) Phytate
(C) Proteins (D) Lactose
21. Calcitriol facilitates calcium absorption by
increasing the synthesis of the following
in intestinal mucosa:
(A) Calcium Binding Protein
(B) Alkaline Phosphatase
(C) Calcium-dependent ATPase
(D) All of these
22. A high plasma calcium level decreases
intestinal absorption of calcium by
(A) Stimulating the secretion of parathormone
(B) Inhibiting the secretion of parathormone
(C) Decreasing the synthesis of cholecalciferol
(D) Inhibiting the secretion of thyrocalcitonin
23. The daily calcium requirement of an adult
man is about
(A) 400 mg (B) 600 mg
(C) 800 mg (D) 1,000 mg
24. The daily calcium requirement in pregnancy
and lactation is about
(A) 600 mg (B) 800 mg
(C) 1,200 mg (D) 1,500 mg
25. Hypercalcaemia can occur in all the following
except
(A) Hyperparathyroidism
(B) Hypervitaminosis D
(C) Milk alkali syndrome
(D) Nephrotic syndrome
26. Hypocalcaemia can occur in all the following
except
(A) Rickets
(B) Osteomalacia
(C) Hyperparathyroidism
(D) Intestinal malabsorption
27. The major calcium salt in bones is
(A) Calcium carbonate
(B) Calcium chloride
(C) Calcium hydroxide
(D) Calcium phosphate
28. The correct statement about serum
inorganic phosphorous concentration is
(A) It is higher in men than in women
(B) It is higher in women than in men
(C) It is higher in adults than in children
(D) It is higher in children than in adults
29. The product of serum calcium concentration
(mg/dl) and serum inorganic phosphorous
concentration (mg/dl) in adults
is about
(A) 30 (B) 40
(C) 50 (D) 60
30. The product of serum calcium concentration
(mg/dl) and serum inorganic phosphorous
concentration (mg/dl) in children
is about
(A) 30 (B) 40
(C) 50 (D) 60