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HORMONE METABOLISM- Part 9
See all quizzes of HORMONE METABOLISM- Part 9 here:
1 The maineffecting of glucagons is to
increase
(A) Glycolysis in muscles
(B) Glycogenolysis in muscles
(C) Glycogenolysis in liver
(D) Glycogenesis in liver
2. Tyrosine is required for the synthesis of
all of the following except
(A) Melatonin (B) Epinephrine
(C) Norepinephrine (D) Thyroxine
3. Dopamine is synthesised from
(A) Dihydroxyphenylalanine
(B) Epinephrine
(C) Norepinephrine
(D) Metanephrine
4. Blood brain barrier can be crossed by
(A) Epinephrine (B) Dopamine
(C) Dopa (D) All of these
5. Epinephrine is synthesised in
(A) Chromaffin cells of adrenal medulla
(B) Sympathetic ganglia
(C) Brain
(D) All of these
6. Immediate precursor of epinephrine is
(A) Metanephrine (B) Norepinephrine
(C) Dopa (D) Dopamine
7. The chief metabolite of catecholamines is
(A) Metanephrine
(B) Normetanephrine
(C) 3, 4-Dihydroxymandelic acid
(D) Vanillylmandelic acid
8. An enzyme involved in catabolism of
catecholamines is
(A) Dopa decarboxylase
(B) Aromatic amino acid decarboxylase
(C) Monoamine oxidase
(D) Catechol oxidas
9. Norepinephrine binds mainly to
(A) α-Adrenergic receptors
(B) β-Adrenergic receptrors
(C) Muscarinic receptors
(D) Nicotinic receptors
10. Astimulatory G-protein transduces the
signals from
(A) α1-and β1-adrenergic receptors
(B) α2-and β2-adrenergic receptors
(C) α1-and α2-adrenergic receptors
(D) β1-and β2-adrenergic receptors
11. Binding of catecholamines to α2−
adrenergic receptors
(A) Increases the intracellular concentration of
cAMP
(B) Increases the intracellular concentration of
cGMP
(C) Decreases the intracellular concentration of
cAMP
(D) Decreases the intracellular concentration of
cGMP
12. Phosphoinositide cascade is activated on
binding of catecholamines to
(A) α1-Adrenergic receptors
(B) α2-Adrenergic receptors
(C) β1-Adrenergic receptors
(D) β2-Adrenergic receptors
13. Epinephrine decreases
(A) Glycogenesis (B) Glycogenolysis
(C) Gluconeogenesis (D) Lipolysis
14. Epinephrine increases the concentration
of free fatty acids in plasma by increasing
(A) Extramitochondrial fatty acid synthesis
(B) Mitochondrial fatty acid chain elongation
(C) Microsomal fatty acid chain elongation
(D) Lipolysis in adipose tissue
15. Epinephrine increases all of the following
except
(A) Glycogenolysis in muscles
(B) Lipolysis in adipose tissue
(C) Gluconeogenesis in muscles
(D) Glucagon secretion
16. Secretion of catecholamines is increased
in
(A) Cushing’s syndrome
(B) Addison’s disease
(C) Phaeochromocytoma
(D) Simmond’s disease
17. Zona glomerulosa of adrenal cortex synthesises
(A) Glucocorticoids
(B) Mineralocorticoids
(C) Androgens
(D) Estrogen and progesterone
18. Cortisol is a
(A) Glucocorticoid (B) Mineralocorticoid
(C) Androgen (D) Estrogen
19. The major mineralcorticoid is
(A) Hydrocortisone (B) Aldosterone
(C) Aldactone A (D) Androstenedione
20. Steroid hormones are synthesised in all
of the following except
(A) Testes (B) Ovaries
(C) Adrenal medulla (D) Adrenal cortex
21. Steroid hormones are synthesised from
(A) Cholesterol
(B) 7-Dehydrocholesterol
(C) Calcitriol
(D) 7-Hydroxycholesterol
22. A common intermediate in the synthesis
of all the steroid hormones is
(A) Pregnenolone
(B) 17-Hydroxypregnenolone
(C) Corticosterone
(D) Progesterone
23. A common intermediate in the synthesis
of cortisol and aldosterone is
(A) Progesterone (B) Testosterone
(C) Estradiol (D) None of these
24. A common intermediate in the synthesis
of estrogens is
(A) Cortisol
(B) Andostenedione
(C) Corticosterone
(D) 11-Deoxycorticosterone
25. Glucocorticoids are transported in blood
(A) In association with transcortin chiefly
(B) In association with albumin to some extent
(C) In free form partly
(D) All of these
26. All the following statements about transcortin
are true except
(A) It is synthesised in liver
(B) It transports glucocorticoids
(C) It transports aldosterone
(D) It transports progesterone
27. The second messenger for glucocorticoids
is
(A) Cyclic AMP
(B) Cyclic GMP
(C) Inositol triphosphate
(D) No second messenger is required
28. Glucocorticoids increase all of the following
except
(A) Gluconeogenesis
(B) Lipolysis in extremities
(C) Synthesis of elcosanoida
(D) Hepatic glycogenesis
29. Glucocorticoids increase the synthesis of
all of the following except
(A) Glucokinase
(B) Glucose-6-phosphatase
(C) Fructose-1, 6-biphosphatase
(D) Pyruvate carboxylase
30. Secretion of glucocorticoida is regulated
by all the following except
(A) Hypothalamus
(B) Anterior pituitary
(C) Feedback control by blood glucose
(D) Feedback control by glucocorticoids
