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FATS AND FATTY ACID METABOLISM- Part 17
See all quizzes of FATS AND FATTY ACID METABOLISM- Part 17 here:
1 All the following statements regarding
ketone bodies are true except
(A) They may result from starvation
(B) They are formed in kidneys
(C) They include acetoacetic acid and acetone
(D) They may be excreted in urine
2. In synthesis of Triglyceride from α-Glycero
phosphate and acetyl CoA, the first
intermediate formed is
(A) β-diacyl glycerol (B) Acyl carnitine
(C) Monoacyl glycerol (D) Phosphatidic acid
3. During each cycle of β-oxidation of fatty
acid, all the following compounds are
generated except
(A) NADH (B) H2O
(C) FAD (D) Acyl CoA
4. The energy yield from complete oxidation
of products generated by second reaction
cycle of β-oxidation of palmitoyl CoA will
be
(A) 5 ATP (B) 12 ATP
(C) 17 ATP (D) 34 ATP
5. β-Oxidation of odd-carbon fatty acid
chain produces
(A) Succinyl CoA (B) Propionyl CoA
(C) Acetyl CoA (D) Malonyl CoA
6. Brown adipose tissue is characterized by
which of the following?
(A) Present in large quantities in adult humans
(B) Mitochondrial content higher than white
adipose tissue
(C) Oxidation and phosphorylation are tightly
coupled
(D) Absent in hibernating animals
7. Ketosis in partly ascribed to
(A) Over production and Glucose
(B) Under production of Glucose
(C) Increased carbohydrate utilization
(D) Increased fat utilization
8. The free fatty acids in blood are
(A) Stored in fat depots
(B) Mainly bound to β-lipoproteins
(C) Mainly bound to serum albumin
(D) Metabolically most inactive
9. Carnitine is synthesized from
(A) Lysine (B) Serine
(C) Choline (D) Arginine
10. A metabolite which is common to pathways
of cholesterol biosynthesis from
acetyl-CoA and cholecalciferol formation
from cholesterol is
(A) Zymosterol
(B) Lumisterol
(C) Ergosterol
(D) 7 Dehydrocholesterol
11. Acetyl CoA required for extra mitochondrial
fatty acid synthesis is produced by
(A) Pyruvate dehydrogenase complex
(B) Citrate lyase
(C) Thiolase
(D) Carnitine-acyl transferase
12. Biosynthesis of Triglyceride and Lecithine
both require an intermediate:
(A) Monoacyl glycerol phosphate
(B) Phosphatidic acid
(C) Phosphatidyl ethanol amine
(D) Phosphatidyl cytidylate
13. The rage limiting step cholesterol biosynthesis
is
(A) Squalene synthetase
(B) Mevalonate kinase
(C) HMG CoA synthetase
(D) HMG CoA reductase
14. All the following are constituents of
ganglioside molecule except
(A) Glycerol (B) Sialic acid
(C) Hexose sugar (D) Sphingosine
15. An alcoholic amine residue is present in
which of the following lipids?
(A) Phosphatidic acid (B) Cholesterol
(C) Sphingomyelin (D) Ganglioside
16. Sphingosine is the backbone of all the
following except
(A) Cerebroside (B) Ceramide
(C) Sphingomyelin (D) Lecithine
17. Chylomicron, intermediate density
lipoproteins (IDL), low density lipoproteins
(LDL) and very low density lipoproteins
(VLDL) all are serum lipoproteins. What is
the correct ordering of these particles from
the lowest to the greatest density?
(A) LDL, IDL, VLDL, Chylomicron
(B) Chylomicron, VLDL, IDL, LDL
(C) VLDL, IDL, LDL, Chylomicron
(D) Chylomicron, IDL, VLDL, LDL
18. A compound normally used to conjugate
bile acids is
(A) Serine (B) Glycine
(C) Glucoronic acid (D) Fatty acid
19. Which of the following lipoproteins
would contribute to a measurement of
plasma cholesterol in a normal person
following a 12 hr fast?
(A) High density lipoprotiens
(B) Low density lipoproteins
(C) Chylomicron
(D) Chylomicron remnants
20. Which of the following products of
triacylglycerol breakdown and subsequent
β-Oxidation may undergo gluconeogenesis?
(A) Acetyl CoA (B) Porpionyl CoA
(C) All ketone bodies (D) Some amino acids
21. Which of the following regulates lipolysis
in adipocytes?
(A) Activation of fatty acid synthesis mediated by
CAMP
(B) Glycerol phosphorylation to prevent futile
esterification of fatty acids
(C) Activation of triglyceride lipase as a result of
hormone stimulated increases in CAMP levels
(D) Activation of CAMP production by Insulin
22. Which one of the following compounds is
a key intermediate in the synthesis of both
triacyl glycerols and phospholipids?
(A) CDP Choline (B) Phosphatidase
(C) Triacyl glyceride (D) Phosphatidyl serine
23. During each cycle of on going fatty acid
oxidation, all the following compounds
are generated except
(A) H2O (B) Acetyl CoA
(C) Fatty acyl CoA (D) NADH
24. All the following statements describing
lipids are true except
(A) They usually associate by covalent interactions
(B) They are structurally components of
membranes
(C) They are an intracellular energy source
(D) They are poorly soluble in H2O
25. All the following statements correctly
describe ketone bodies except
(A) They may result from starvation
(B) They are present at high levels in uncontrolled
diabetes
(C) They include—OH β-butyrate and acetone
(D) They are utilized by the liver during long term
starvation
26. Which of the following features is
predicted by the Nicolson–Singer fluid
mosaic model of biological membranes?
(A) Membrane lipids do not diffuse laterally
(B) Membrane lipid is primarily in a monolayer
form
(C) Membrane lipids freely flip-flop
(D) Membrane proteins may diffuse laterally
27. Oxidative degradation of acetyl CoA in
the citric acid cycle gives a net yield of all
the following except
(A) FADH2 (B) 3 NADH
(C) 2 ATP (D) 2CO2
28. All the following correctly describe the
intermediate 3-OH-3-methyl glutaryl CoA
except
(A) It is generated enzymatically in the
mitochondrial matrix
(B) It is formed in the cytoplasm
(C) It inhibits the first step in cholesterol synthesis
(D) It is involved in the synthesis of ketone bodies
29. Intermediate in the denovo synthesis of
triacyl glycerols include all the following
except
(A) Fatty acyl CoA
(B) CDP diacyl glycerol
(C) Glycerol-3-phosphate
(D) Lysophosphatidic acid
30. Mitochondrial α-ketoglutarate dehydrogenase
complex requires all the following
to function except
(A) CoA (B) FAD
(C) NAD+ (D) NADP+
