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ENZYMES- Part 13
See all quizzes of ENZYMES- Part 13 here:
1 Therapeutic enzymes:
(A) Streptokinase (B) Asparaginase
(C) Riboflavinase (D) Both (A) and (B)
2. A gluconeogenic enzyme among the
following is
(A) Phosphofructokinase
(B) Pyruvate kinase
(C) Phosphoenol pyruvate carboxykinase
(D) Glucokinase
3. Glucose-6-phosphatase and PEP carboxy
kinase are regulated by
(A) Covalent modification
(B) Allosteric regulation
(C) Induction and repression
(D) All of these
4. The maximum possible chain length of
fatty acids formed in the pathway of de
novo synthesis is
(A) 16 Carbon atoms (B) 18 Carbon atoms
(C) 20 Carbon atoms (D) 24 Carbon atoms
5. Acetyl CoA required for de novo synthesis
of fatty acids is obtained from
(A) Breakdown of existing fatty acids
(B) Ketone bodies
(C) Acetate
(D) Pyruvate
6. Formation of acetyl CoA from pyruvate
for de novo synthesis of fatty acids requires
(A) Pyruvate dehydrogenase complex
(B) Citrate synthetase
(C) ATP citrate lyase
(D) All of these
7. The major site for elongation of medium
chain fatty acids is
(A) Mitochondria (B) Cytosol
(C) Microsomes (D) All of these
8. β-oxidation of fatty acids is inhibited by
(A) NADPH (B) Acetyl CoA
(C) Malonyl CoA (D) None of these
9. The enzyme regulating extramitochondrial
fatty acid synthesis is
(A) Thioesterase
(B) Acetyl CoA carboxylase
(C) Acyl transferase
(D) Multi-enzyme complex
10. Acetyl CoA carboxylase is activated by
(A) Citrate (B) Insulin
(C) Both (A) and (B) (D) None of these
11. All the following statements about acetyl
CoA carboxylase are true except:
(A) It is activated by citrate
(B) It is inhibited by palmitoyl CoA
(C) It can undergo covalent modification
(D) Its dephosphorylated form is inactive
12. All the following statements about acetyl
CoA carboxylase are true except
(A) It is required for de novo synthesis of fatty
acids
(B) It is required for mitochondrial elongation of
fatty acids
(C) It is required for microsomal elongation of fatty
acids
(D) Insulin converts its inactive form into its active
form
13. Both Acyl carrier protein (ACP) of fatty
acid synthetase and coenzyme (CoA) are
(A) Contain reactive phosphorylated
(B) Contain thymidine
(C) Contain phosphopantetheine reactive groups
(D) Contain cystine reactive groups
14. Which one of the following transfers acyl
groups?
(A) Thiamine pyrophosphate
(B) Lipomide
(C) ATP
(D) NADH
15. Which one of the following cofactors must
be utilized during the conversion of acetyl
CoA to malonyl CoA?
(A) TPP (B) ACP
(C) NAD+ (D) Biotin
16. Which one of the following enzymes
requires a coenzyme derived from the
vitamin whose structure is shown below?
(A) Enoyl CoA hydratase
(B) Phosphofructokinase
(C) Glucose-6-phosphatase
(D) Glucose-6-phosphate dehydrogenase
17. Coenzymes derived from the vitamin
shown below are required by enzymes
involved in the synthesis of which of the
following?
(A) ATP (B) UTP
(C) CTP (D) NADH
18. Coenzymes derived from the vitamin
shown below are required by which of
the following enzymes?
(A) Lactate dehydrogenase
(B) Glutamate dehydrogenase
(C) Pyruvate dehydrogenase
(D) Malate dehydrogenase
19. All the following are coenzymes except
(A) Ubiquinone
(B) CoA
(C) Pyruvate dehydrogenase
(D) Lipoic acid
20. Which of the following is not a cofactor?
(A) Mg (B) Iron
(C) Cu (D) Methylcobalamine
21. All the following compounds are
members of the electron transport chain
except
(A) Ubiquinone (B) Carnitine
(C) NAD (D) FAD
22. Thiamine is essential for
(A) Pyruvate dehydrogenase
(B) Isocitrate dehydrogenase
(C) Succinate dehydrogenase
(D) Acetyl CoA synthetase
23. Adenylate cyclase is activated by
(A) Insulin (B) Glucagon
(C) Prostaglandin E1 (D) Ca2+ ions
24. Maximum enzyme activity is observed at
(A) Acidic pH (B) Neutral pH
(C) Basic pH (D) Optimum pH
25. Which of the following is known as bone
forming enzyme?
(A) Alkaline phosphatase
(B) Acid phosphatase
(C) Leucine aminopeptidase
(D) γ-glutamyl transpeptidase
26. Conversion of pepsinogen to pepsin is
(A) Intra molecular rearrangement
(B) Breaking of hydrogen bonds
(C) Covalent modification
(D) Polymerisation
27. Which of the following is not having an
apoenzyme and coenzyme?
(A) Lactate dehydrogenase
(B) Succinate dehydrogenase
(C) Malate dehydrogenase
(D) Pepsin
28. Pyruvate dehydrogenase is a/an
(A) Isomerase (B) Lyase
(C) Ligase (D) Oxido reductase
29. Homogentisic oxidase is an
(A) Oxidase
(B) Monooxygenase
(C) Dioxygenase
(D) Anaerotic dehydrogenase
30. Isocitrate dehydrogenase can use
__________ as a cofactor.
(A) NAD+ only (B) NADP+ only
(C) NAD+ or NADP+ (D) FMN and FAD
