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PROTEINS AND PROTEIN METABOLISM- Part 16
See all quizzes of PROTEINS AND PROTEIN METABOLISM- Part 16 here:
1 In the synthesis of 1 molecule of urea in
the Kreb’s Hanseleit cycle, the number of
ATPs required is
(A) 1 (B) 2
(C) 3 (D) 4
2. For biosynthesis of proteins
(A) Amino acids only are required
(B) Amino acids and nucleic acids only are
required
(C) Amino acid, nucleic acids and ATP only are
required
(D) Amino acids, nucleic acids, ATP, GTP,
enzymes and activators are required
3. Transmethylation of guanido acetic acid
gives
(A) Creatine phosphate
(B) Creatinine
(C) Choline
(D) n-methyl nicotinamide
4. The 2 energy rich compounds needed for
protein biosynthesis are
(A) ATP and GTP (B) ATP and UTP
(C) ATP and CTP (D) ATP and TTP
5. The following ketoacid is involved in
fixing dietary NH3 into amino acid:
(A) Pyruvate (B) Oxalo acetate
(C) Oxalo succinate (D) α-keto glutarate
6. The metabolite which sustains urea cycle
is
(A) Ornithine
(B) Citrulline
(C) Carbamoyl phosphate
(D) n-acetyl glutamate
7. Tetra hydroglolate can be freed from N5
methyl tetrahydrofolate only by
(A) Nor epinephrine (B) Ethanol amine
(C) Nicotinamide (D) Vitamin B12
8. Neogenesis of methyl group is
(A) The availability of methyl group form δ
adenosyl methionine
(B) The availability of methyl group from betaine
(C) Interaction between N5 N10 methylene tetra
hydrofolate with a NAD+ dependent
reductase
(D) Availability of methyl group from methyl B12
9. More creatinine is excreted by
(A) Adult males (B) Adult females
(C) Children (D) Pregnant women
10. A growing peptide in a ribosome can not
be shifted to the adjacent ribosome
because
(A) It is firmly attached
(B) It will get the amino acid cleaved
(C) The gap between the ribosomes is too big for
a shift
(D) The adjacent ribosomes have different
composition
11. The first amino acid incorporated in a
polypeptide in a ribosome of a human is
(A) N formyl methionine (B) Methionine
(C) Phenyl alanine (D) Hydroxy lysine
12. The first amino acid incorporated in a
polypeptide in a ribosome of a bacterium
is
(A) N formyl methionine (B) Methionine
(C) Alamine (D) Glycine
13. The integrator between the TCA cycle and
urea cycle is
(A) Fumarate (B) Malate
(C) Pyruvate (D) Citrate
14. Bence jones proteinurial characterized by
(A) Non-heat coagulability
(B) Heat coagulability at 100°C
(C) Heat coagulability at 45 to 60°C
(D) Precipitation at 25°C
15. Bence Jones proteins may be excreted in
urine of patients suffering from
(A) Tuberculosis (B) Diabetes mellitus
(C) Multiple myeloma (D) Hyperthyroidism
16. Xanthuric acid is an abnormal metabolite
of
(A) Xanthine (B) Uric acid
(C) Tyrosine (D) Tryptophan
17. Two nitrogen atoms of Urea in the urea
cycle come from
(A) NH3
(B) One from NH3 and one from aspartate
(C) One from NH3 and one from glutamate
(D) One from NH3 and one from alanine
18. Pyruvic acid can be obtained by transamination
of alanine with
(A) α- keto glutaric acid
(B) Acetoacetic acid
(C) β−OH butyric acid
(D) Phosphoenol Pyruvic acid
19. In the synthesis of 1 molecule of urea in
the Kreb’s Henseleit cycle the number of
AMPs formed is
(A) 1 (B) 2
(C) 3 (D) 4
20. Formation of melanin from tyrosine
requires the action of
(A) Dopa decarboxylation
(B) Diamine oxidase
(C) Peroxidase
(D) Tyrosinase
21. In one of the following the quality of the
protein synthesized is affected:
(A) Diabetes mellitus (B) Gont
(C) Multiple myeloma (D) Primaquine sensitivity
22. Citrulline is an intermediate of
(A) TCA cycle (B) Urea cycle
(C) Pentose cycle (D) Calvin cycle
23. The semialdehydes are formed under the
action of enzymes characterised as
(A) Aldolases
(B) Peptidyl lysyl oxidases
(C) Collagenases
(D) Elastases
24. Which of the following statement about
the peptide bond is true?
(A) It is a carbon-carbon bond
(B) It has cis hydrogen and oxygen groups
(C) It is planar
(D) It has rotational freedom
25. Isoenzymes for a given reaction
(A) Have different spedificities
(B) Have identical affinities for the same substrate
(C) Exhibit different electrophoretic motilities
(D) Contain similar ratios of different polypeptide
chains
26. The highest concentration of cystine can
be found in
(A) Melanin (B) Chondroitin sulphate
(C) Myosin (D) Keratin
27. One round of Edman degradation of the
peptide: H2N— Gly—Arg—Lys—Phe—
Asp— COOH would result in which of the
following structures or their phenyl isothiocyanate
derivatives?
(A) H2N—Gly—Arg—COOH + H2N—Lys—
Phe— Asp—COOH
(B) H2N—Gly—Arg—Lys—Phe—COOH + Asp
(C) H2N—Arg—Lys—Phe—Asp—COOH + Gly
(D) H2N—Gly—Arg—Lys—COOH + H2N—Phe
—Asp—COOH
28. Which of the following techniques is used
to separate proteins based upon differences
in their mass?
(A) Isoelectric focusing
(B) Dialysis
(C) SDS-gel Electrophoresis
(D) Western blotting
29. The greatest buffering capacity at
physiologic pH would be provided by a
protein rich in which of the following
amino acids ?
(A) Lysine (B) Histidine
(C) Aspartic acid (D) Valine
30. Which one of the amino acids could serve
as the best buffer at pH 7?
(A) Glutamic acid (B) Arginine
(C) Valine (D) Histidine
