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PROTEINS AND PROTEIN METABOLISM- Part 3
See all quizzes of PROTEINS AND PROTEIN METABOLISM- Part 3 here:
1 Both α-helix and β-pleated sheet conformation
of proteins were proposed by
(A) Watson and Crick
(B) Pauling and Corey
(C) Waugh and King
(D) Y.S.Rao
2. The primary structure of fibroin, the
principal protein of silk worm fibres
consists almost entirely of
(A) Glycine (B) Aspartate
(C) Keratin (D) Tryptophan
3. Tertiary structure of a protein describes
(A) The order of amino acids
(B) Location of disulphide bonds
(C) Loop regions of proteins
(D) The ways of protein folding
4. In a protein molecule the disulphide bond
is not broken by
(A) Reduction
(B) Oxidation
(C) Denaturation
(D) X-ray diffraction
5. The technique for purification of proteins
that can be made specific for a given
protein is
(A) Gel filtration chromotography
(B) Ion exchange chromatography
(C) Electrophoresis
(D) Affinity chromatography
6. Denaturation of proteins results in
(A) Disruption of primary structure
(B) Breakdown of peptide bonds
(C) Destruction of hydrogen bonds
(D) Irreversible changes in the molecule
7. Ceruloplasmin is
(A) α1-globulin (B) α2-globulin
(C) β-globulin (D) None of these
8. The lipoprotein with the fastest electrophoretic
mobility and the lowest triglyceride
content is
(A) Chylomicron (B) VLDL
(C) IDL (D) HDL
9. The lipoprotein associated with activation
of LCAT is
(A) HDL (B) LDL
(C) VLDL (D) IDL
10. The apolipoprotein which acts as activator
of LCAT is
(A) A-I (B) A-IV
(C) C-II (D) D
11. The apolipoprotein which acts as actiator
of extrahepatic lipoprotein is
(A) Apo-A (B) Apo-B
(C) Apo-C (D) Apo-D
12. The apolipoprotein which forms the
integral component of chylomicron is
(A) B-100 (B) B-48
(C) C (D) D
13. The apolipoprotein which from the
integral component of VLDL is
(A) B-100 (B) B-48
(C) A (D) D
14. The apolipoprotein which acts as ligand
for LDL receptor is
(A) B-48 (B) B-100
(C) A (D) C
15. Serum LDL has been found to be increased
in
(A) Obstructive jaundice
(B) Hepatic jaundice
(C) Hemolytic jaundice
(D) Malabsorption syndrome
16. A lipoprotein associated with high
incidence of coronary atherosclerosis is
(A) LDL (B) VLDL
(C) IDL (D) HDL
17. A lipoprotein inversely related to the
incidence of coronary artherosclerosis is
(A) VLDL (B) IDL
(C) LDL (D) HDL
18. The primary biochemical lesion in homozygote
with familial hypercholesterolemia
(type IIa) is
(A) Loss of feed back inhibition of HMG
reductase
(B) Loss of apolipoprotein B
(C) Increased production of LDL from VLDL
(D) Functional deficiency of plasma membrane
receptors for LDL
19. In abetalipoproteinemia, the biochemical
defect is in
(A) Apo-B synthesis
(B) Lipprotein lipase activity
(C) Cholesterol ester hydrolase
(D) LCAT activity
20. Familial hypertriaacylglycerolemia is
associated with
(A) Over production of VLDL
(B) Increased LDL concentration
(C) Increased HDL concentration
(D) Slow clearance of chylomicrons
21. For synthesis of prostaglandins, the
essential fatty acids give rise to a fatty
acid containing
(A) 12 carbon atoms (B) 16 carbon atoms
(C) 20 carbon atoms (D) 24 carbon atoms
22. All active prostaglandins have at least one
double bond between positions
(A) 7 and 8 (B) 10 and 11
(C) 13 and 14 (D) 16 and 17
23. Normal range of plasma total phospholipids
is
(A) 0.2–0.6 mmol/L (B) 0.9–2.0 mmol/L
(C) 1.8–5.8 mmol/L (D) 2.8–5.3 mmol/L
24. HDL2 have the density in the range of
(A) 1.006–1.019 (B) 1.019–1.032
(C) 1.032–1.063 (D) 1.063–1.125
25. β-lipoproteins have the density in the
range of
(A) 0.95–1.006 (B) 1.006–1.019
(C) 1.019–1.063 (D) 1.063–1.125
26. IDL have the density in the range of
(A) 0.95–1.006 (B) 1.006–1.019
(C) 1.019–1.032 (D) 1.032–1.163
27. Aspirin inhibits the activity of the enzyme:
(A) Lipoxygenase (B) Cyclooxygenase
(C) Phospholipae A1 (D) Phospholipase A2
28. A ’suicide enzyme’ is
(A) Cycloxygenase (B) Lipooxygenase
(C) Phospholipase A1 (D) Phospholipase A2
29. In adipose tissue prostaglandins
decrease
(A) Lipogenesis (B) Lipolysis
(C) Gluconeogenesis (D) Glycogenolysis
30 The optimal pH for the enzyme pepsin is
(A) 1.0–2.0 (B) 4.0–5.0
(C) 5.2–?6.0 (D) 5.8–6.2
